3,955 research outputs found
SKIRT: hybrid parallelization of radiative transfer simulations
We describe the design, implementation and performance of the new hybrid
parallelization scheme in our Monte Carlo radiative transfer code SKIRT, which
has been used extensively for modeling the continuum radiation of dusty
astrophysical systems including late-type galaxies and dusty tori. The hybrid
scheme combines distributed memory parallelization, using the standard Message
Passing Interface (MPI) to communicate between processes, and shared memory
parallelization, providing multiple execution threads within each process to
avoid duplication of data structures. The synchronization between multiple
threads is accomplished through atomic operations without high-level locking
(also called lock-free programming). This improves the scaling behavior of the
code and substantially simplifies the implementation of the hybrid scheme. The
result is an extremely flexible solution that adjusts to the number of
available nodes, processors and memory, and consequently performs well on a
wide variety of computing architectures.Comment: 21 pages, 20 figure
Optical tomography using the SCIRun problem solving environment: Preliminary results for three-dimensional geometries and parallel processing
We present a 3D implementation of the UCL imaging package for absorption and scatter reconstruction from time-resolved data (TOAST), embedded in the SCIRun interactive simulation and visualization package developed at the University of Utah. SCIRun is a scientific programming environment that allows the interactive construction, debugging, and steering of large-scale scientific computations. While the capabilities of SCIRun's interactive approach are not yet fully exploited in the current TOAST implementation, an immediate benefit of the combined TOAST/SCIRun package is the availability of optimized parallel finite element forward solvers, and the use of SCIRun's existing 3D visualisation tools. A reconstruction of a segmented 3D head model is used as an example for demonstrating the capability of TOAST/SCIRun of simulating anatomically shaped meshes
Quantum ESPRESSO: a modular and open-source software project for quantum simulations of materials
Quantum ESPRESSO is an integrated suite of computer codes for
electronic-structure calculations and materials modeling, based on
density-functional theory, plane waves, and pseudopotentials (norm-conserving,
ultrasoft, and projector-augmented wave). Quantum ESPRESSO stands for "opEn
Source Package for Research in Electronic Structure, Simulation, and
Optimization". It is freely available to researchers around the world under the
terms of the GNU General Public License. Quantum ESPRESSO builds upon
newly-restructured electronic-structure codes that have been developed and
tested by some of the original authors of novel electronic-structure algorithms
and applied in the last twenty years by some of the leading materials modeling
groups worldwide. Innovation and efficiency are still its main focus, with
special attention paid to massively-parallel architectures, and a great effort
being devoted to user friendliness. Quantum ESPRESSO is evolving towards a
distribution of independent and inter-operable codes in the spirit of an
open-source project, where researchers active in the field of
electronic-structure calculations are encouraged to participate in the project
by contributing their own codes or by implementing their own ideas into
existing codes.Comment: 36 pages, 5 figures, resubmitted to J.Phys.: Condens. Matte
Fast, Scalable, and Interactive Software for Landau-de Gennes Numerical Modeling of Nematic Topological Defects
Numerical modeling of nematic liquid crystals using the tensorial Landau-de
Gennes (LdG) theory provides detailed insights into the structure and
energetics of the enormous variety of possible topological defect
configurations that may arise when the liquid crystal is in contact with
colloidal inclusions or structured boundaries. However, these methods can be
computationally expensive, making it challenging to predict (meta)stable
configurations involving several colloidal particles, and they are often
restricted to system sizes well below the experimental scale. Here we present
an open-source software package that exploits the embarrassingly parallel
structure of the lattice discretization of the LdG approach. Our
implementation, combining CUDA/C++ and OpenMPI, allows users to accelerate
simulations using both CPU and GPU resources in either single- or multiple-core
configurations. We make use of an efficient minimization algorithm, the Fast
Inertial Relaxation Engine (FIRE) method, that is well-suited to large-scale
parallelization, requiring little additional memory or computational cost while
offering performance competitive with other commonly used methods. In
multi-core operation we are able to scale simulations up to supra-micron length
scales of experimental relevance, and in single-core operation the simulation
package includes a user-friendly GUI environment for rapid prototyping of
interfacial features and the multifarious defect states they can promote. To
demonstrate this software package, we examine in detail the competition between
curvilinear disclinations and point-like hedgehog defects as size scale,
material properties, and geometric features are varied. We also study the
effects of an interface patterned with an array of topological point-defects.Comment: 16 pages, 6 figures, 1 youtube link. The full catastroph
Electromagnetic Stirring in a Microbioreactor with Non-conventional Chamber Morphology and Implementation of Multiplexed Mixing
© 2015 The Authors. Journal of Chemical Technology & Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.Background: Microbioreactors have recently emerged as novel tools for early bioprocess development. Mixing lies at the heart of bioreactor operation (at all scales), and the successful implementation of micro-stirring methods is thus central to the further advancement of microbioreactor technology. The aim of this study was to develop a micro-stirring method that aids robust microbioreactor operation and facilitates cost effective parallelization. Results: We developed a microbioreactor with a novel micro-stirring method involving the movement of a magnetic bead by sequenced activation of a ring of electromagnets. The micro-stirring method offers flexibility in chamber designs and we demonstrate mixing in cylindrical, diamond and triangular shaped reactor chambers. Mixing times between the cylindrical and diamond-shaped chamber compared well, with the shortest mixing times in both being 3.4 s. Ease of micro-bubble free priming, a typical challenge of cylindrical microbioreactor chambers, was obtained with diamond shaped chamber. Consistent mixing behaviour was observed between the constituent reactors in a duplex system, and batch and continuous culture fermentation of Staphylococcus carnosus successfully performed. Conclusion: A novel stirring method using electromagnetic actuation offering rapid mixing and easy integration with microbioreactors was characterized. The gained design flexibility enables fabrication of chambers suitable for microfluidic operation, and a duplex demonstrator highlights potential for cost-effective parallelization. Combined with a previously published cassette-like fabrication of microbioreactors, these advances will facilitate the development of robust parallelized systems for both batch and chemostat bioreactor operation.Peer reviewe
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