4,735 research outputs found

    CHAMMI: A benchmark for channel-adaptive models in microscopy imaging

    Full text link
    Most neural networks assume that input images have a fixed number of channels (three for RGB images). However, there are many settings where the number of channels may vary, such as microscopy images where the number of channels changes depending on instruments and experimental goals. Yet, there has not been a systemic attempt to create and evaluate neural networks that are invariant to the number and type of channels. As a result, trained models remain specific to individual studies and are hardly reusable for other microscopy settings. In this paper, we present a benchmark for investigating channel-adaptive models in microscopy imaging, which consists of 1) a dataset of varied-channel single-cell images, and 2) a biologically relevant evaluation framework. In addition, we adapted several existing techniques to create channel-adaptive models and compared their performance on this benchmark to fixed-channel, baseline models. We find that channel-adaptive models can generalize better to out-of-domain tasks and can be computationally efficient. We contribute a curated dataset (https://doi.org/10.5281/zenodo.7988357) and an evaluation API (https://github.com/broadinstitute/MorphEm.git) to facilitate objective comparisons in future research and applications.Comment: Accepted at NeurIPS Track on Datasets and Benchmarks, 202

    Serverless Strategies and Tools in the Cloud Computing Continuum

    Full text link
    Tesis por compendio[ES] En los últimos años, la popularidad de la computación en nube ha permitido a los usuarios acceder a recursos de cómputo, red y almacenamiento sin precedentes bajo un modelo de pago por uso. Esta popularidad ha propiciado la aparición de nuevos servicios para resolver determinados problemas informáticos a gran escala y simplificar el desarrollo y el despliegue de aplicaciones. Entre los servicios más destacados en los últimos años se encuentran las plataformas FaaS (Función como Servicio), cuyo principal atractivo es la facilidad de despliegue de pequeños fragmentos de código en determinados lenguajes de programación para realizar tareas específicas en respuesta a eventos. Estas funciones son ejecutadas en los servidores del proveedor Cloud sin que los usuarios se preocupen de su mantenimiento ni de la gestión de su elasticidad, manteniendo siempre un modelo de pago por uso de grano fino. Las plataformas FaaS pertenecen al paradigma informático conocido como Serverless, cuyo propósito es abstraer la gestión de servidores por parte de los usuarios, permitiéndoles centrar sus esfuerzos únicamente en el desarrollo de aplicaciones. El problema del modelo FaaS es que está enfocado principalmente en microservicios y tiende a tener limitaciones en el tiempo de ejecución y en las capacidades de computación (por ejemplo, carece de soporte para hardware de aceleración como GPUs). Sin embargo, se ha demostrado que la capacidad de autoaprovisionamiento y el alto grado de paralelismo de estos servicios pueden ser muy adecuados para una mayor variedad de aplicaciones. Además, su inherente ejecución dirigida por eventos hace que las funciones sean perfectamente adecuadas para ser definidas como pasos en flujos de trabajo de procesamiento de archivos (por ejemplo, flujos de trabajo de computación científica). Por otra parte, el auge de los dispositivos inteligentes e integrados (IoT), las innovaciones en las redes de comunicación y la necesidad de reducir la latencia en casos de uso complejos han dado lugar al concepto de Edge computing, o computación en el borde. El Edge computing consiste en el procesamiento en dispositivos cercanos a las fuentes de datos para mejorar los tiempos de respuesta. La combinación de este paradigma con la computación en nube, formando arquitecturas con dispositivos a distintos niveles en función de su proximidad a la fuente y su capacidad de cómputo, se ha acuñado como continuo de la computación en la nube (o continuo computacional). Esta tesis doctoral pretende, por lo tanto, aplicar diferentes estrategias Serverless para permitir el despliegue de aplicaciones generalistas, empaquetadas en contenedores de software, a través de los diferentes niveles del continuo computacional. Para ello, se han desarrollado múltiples herramientas con el fin de: i) adaptar servicios FaaS de proveedores Cloud públicos; ii) integrar diferentes componentes software para definir una plataforma Serverless en infraestructuras privadas y en el borde; iii) aprovechar dispositivos de aceleración en plataformas Serverless; y iv) facilitar el despliegue de aplicaciones y flujos de trabajo a través de interfaces de usuario. Además, se han creado y adaptado varios casos de uso para evaluar los desarrollos conseguidos.[CA] En els últims anys, la popularitat de la computació al núvol ha permès als usuaris accedir a recursos de còmput, xarxa i emmagatzematge sense precedents sota un model de pagament per ús. Aquesta popularitat ha propiciat l'aparició de nous serveis per resoldre determinats problemes informàtics a gran escala i simplificar el desenvolupament i desplegament d'aplicacions. Entre els serveis més destacats en els darrers anys hi ha les plataformes FaaS (Funcions com a Servei), el principal atractiu de les quals és la facilitat de desplegament de petits fragments de codi en determinats llenguatges de programació per realitzar tasques específiques en resposta a esdeveniments. Aquestes funcions són executades als servidors del proveïdor Cloud sense que els usuaris es preocupen del seu manteniment ni de la gestió de la seva elasticitat, mantenint sempre un model de pagament per ús de gra fi. Les plataformes FaaS pertanyen al paradigma informàtic conegut com a Serverless, el propòsit del qual és abstraure la gestió de servidors per part dels usuaris, permetent centrar els seus esforços únicament en el desenvolupament d'aplicacions. El problema del model FaaS és que està enfocat principalment a microserveis i tendeix a tenir limitacions en el temps d'execució i en les capacitats de computació (per exemple, no té suport per a maquinari d'acceleració com GPU). Tot i això, s'ha demostrat que la capacitat d'autoaprovisionament i l'alt grau de paral·lelisme d'aquests serveis poden ser molt adequats per a més aplicacions. A més, la seva inherent execució dirigida per esdeveniments fa que les funcions siguen perfectament adequades per ser definides com a passos en fluxos de treball de processament d'arxius (per exemple, fluxos de treball de computació científica). D'altra banda, l'auge dels dispositius intel·ligents i integrats (IoT), les innovacions a les xarxes de comunicació i la necessitat de reduir la latència en casos d'ús complexos han donat lloc al concepte d'Edge computing, o computació a la vora. L'Edge computing consisteix en el processament en dispositius propers a les fonts de dades per millorar els temps de resposta. La combinació d'aquest paradigma amb la computació en núvol, formant arquitectures amb dispositius a diferents nivells en funció de la proximitat a la font i la capacitat de còmput, s'ha encunyat com a continu de la computació al núvol (o continu computacional). Aquesta tesi doctoral pretén, doncs, aplicar diferents estratègies Serverless per permetre el desplegament d'aplicacions generalistes, empaquetades en contenidors de programari, a través dels diferents nivells del continu computacional. Per això, s'han desenvolupat múltiples eines per tal de: i) adaptar serveis FaaS de proveïdors Cloud públics; ii) integrar diferents components de programari per definir una plataforma Serverless en infraestructures privades i a la vora; iii) aprofitar dispositius d'acceleració a plataformes Serverless; i iv) facilitar el desplegament d'aplicacions i fluxos de treball mitjançant interfícies d'usuari. A més, s'han creat i s'han adaptat diversos casos d'ús per avaluar els desenvolupaments aconseguits.[EN] In recent years, the popularity of Cloud computing has allowed users to access unprecedented compute, network, and storage resources under a pay-per-use model. This popularity led to new services to solve specific large-scale computing challenges and simplify the development and deployment of applications. Among the most prominent services in recent years are FaaS (Function as a Service) platforms, whose primary appeal is the ease of deploying small pieces of code in certain programming languages to perform specific tasks on an event-driven basis. These functions are executed on the Cloud provider's servers without users worrying about their maintenance or elasticity management, always keeping a fine-grained pay-per-use model. FaaS platforms belong to the computing paradigm known as Serverless, which aims to abstract the management of servers from the users, allowing them to focus their efforts solely on the development of applications. The problem with FaaS is that it focuses on microservices and tends to have limitations regarding the execution time and the computing capabilities (e.g. lack of support for acceleration hardware such as GPUs). However, it has been demonstrated that the self-provisioning capability and high degree of parallelism of these services can be well suited to broader applications. In addition, their inherent event-driven triggering makes functions perfectly suitable to be defined as steps in file processing workflows (e.g. scientific computing workflows). Furthermore, the rise of smart and embedded devices (IoT), innovations in communication networks and the need to reduce latency in challenging use cases have led to the concept of Edge computing. Edge computing consists of conducting the processing on devices close to the data sources to improve response times. The coupling of this paradigm together with Cloud computing, involving architectures with devices at different levels depending on their proximity to the source and their compute capability, has been coined as Cloud Computing Continuum (or Computing Continuum). Therefore, this PhD thesis aims to apply different Serverless strategies to enable the deployment of generalist applications, packaged in software containers, across the different tiers of the Cloud Computing Continuum. To this end, multiple tools have been developed in order to: i) adapt FaaS services from public Cloud providers; ii) integrate different software components to define a Serverless platform on on-premises and Edge infrastructures; iii) leverage acceleration devices on Serverless platforms; and iv) facilitate the deployment of applications and workflows through user interfaces. Additionally, several use cases have been created and adapted to assess the developments achieved.Risco Gallardo, S. (2023). Serverless Strategies and Tools in the Cloud Computing Continuum [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/202013Compendi

    Classical and quantum algorithms for scaling problems

    Get PDF
    This thesis is concerned with scaling problems, which have a plethora of connections to different areas of mathematics, physics and computer science. Although many structural aspects of these problems are understood by now, we only know how to solve them efficiently in special cases.We give new algorithms for non-commutative scaling problems with complexity guarantees that match the prior state of the art. To this end, we extend the well-known (self-concordance based) interior-point method (IPM) framework to Riemannian manifolds, motivated by its success in the commutative setting. Moreover, the IPM framework does not obviously suffer from the same obstructions to efficiency as previous methods. It also yields the first high-precision algorithms for other natural geometric problems in non-positive curvature.For the (commutative) problems of matrix scaling and balancing, we show that quantum algorithms can outperform the (already very efficient) state-of-the-art classical algorithms. Their time complexity can be sublinear in the input size; in certain parameter regimes they are also optimal, whereas in others we show no quantum speedup over the classical methods is possible. Along the way, we provide improvements over the long-standing state of the art for searching for all marked elements in a list, and computing the sum of a list of numbers.We identify a new application in the context of tensor networks for quantum many-body physics. We define a computable canonical form for uniform projected entangled pair states (as the solution to a scaling problem), circumventing previously known undecidability results. We also show, by characterizing the invariant polynomials, that the canonical form is determined by evaluating the tensor network contractions on networks of bounded size

    LIPIcs, Volume 251, ITCS 2023, Complete Volume

    Get PDF
    LIPIcs, Volume 251, ITCS 2023, Complete Volum

    A Critical Review Of Post-Secondary Education Writing During A 21st Century Education Revolution

    Get PDF
    Educational materials are effective instruments which provide information and report new discoveries uncovered by researchers in specific areas of academia. Higher education, like other education institutions, rely on instructional materials to inform its practice of educating adult learners. In post-secondary education, developmental English programs are tasked with meeting the needs of dynamic populations, thus there is a continuous need for research in this area to support its changing landscape. However, the majority of scholarly thought in this area centers on K-12 reading and writing. This paucity presents a phenomenon to the post-secondary community. This research study uses a qualitative content analysis to examine peer-reviewed journals from 2003-2017, developmental online websites, and a government issued document directed toward reforming post-secondary developmental education programs. These highly relevant sources aid educators in discovering informational support to apply best practices for student success. Developmental education serves the purpose of addressing literacy gaps for students transitioning to college-level work. The findings here illuminate the dearth of material offered to developmental educators. This study suggests the field of literacy research is fragmented and highlights an apparent blind spot in scholarly literature with regard to English writing instruction. This poses a quandary for post-secondary literacy researchers in the 21st century and establishes the necessity for the literacy research community to commit future scholarship toward equipping college educators teaching writing instruction to underprepared adult learners

    Quantum simulation of battery materials using ionic pseudopotentials

    Full text link
    Ionic pseudopotentials are widely used in classical simulations of materials to model the effective potential due to the nucleus and the core electrons. Modeling fewer electrons explicitly results in a reduction in the number of plane waves needed to accurately represent the states of a system. In this work, we introduce a quantum algorithm that uses pseudopotentials to reduce the cost of simulating periodic materials on a quantum computer. We use a qubitization-based quantum phase estimation algorithm that employs a first-quantization representation of the Hamiltonian in a plane-wave basis. We address the challenge of incorporating the complexity of pseudopotentials into quantum simulations by developing highly-optimized compilation strategies for the qubitization of the Hamiltonian. This includes a linear combination of unitaries decomposition that leverages the form of separable pseudopotentials. Our strategies make use of quantum read-only memory subroutines as a more efficient alternative to quantum arithmetic. We estimate the computational cost of applying our algorithm to simulating lithium-excess cathode materials for batteries, where more accurate simulations are needed to inform strategies for gaining reversible access to the excess capacity they offer. We estimate the number of qubits and Toffoli gates required to perform sufficiently accurate simulations with our algorithm for three materials: lithium manganese oxide, lithium nickel-manganese oxide, and lithium manganese oxyfluoride. Our optimized compilation strategies result in a pseudopotential-based quantum algorithm with a total runtime four orders of magnitude lower than the previous state of the art for a fixed target accuracy

    Software Test Case Generation Tools and Techniques: A Review

    Get PDF
    Software Industry is evolving at a very fast pace since last two decades. Many software developments, testing and test case generation approaches have evolved in last two decades to deliver quality products and services. Testing plays a vital role to ensure the quality and reliability of software products. In this paper authors attempted to conduct a systematic study of testing tools and techniques. Six most popular e-resources called IEEE, Springer, Association for Computing Machinery (ACM), Elsevier, Wiley and Google Scholar to download 738 manuscripts out of which 125 were selected to conduct the study. Out of 125 manuscripts selected, a good number approx. 79% are from reputed journals and around 21% are from good conference of repute. Testing tools discussed in this paper have broadly been divided into five different categories: open source, academic and research, commercial, academic and open source, and commercial & open source. The paper also discusses several benchmarked datasets viz. Evosuite 10, SF100 Corpus, Defects4J repository, Neo4j, JSON, Mocha JS, and Node JS to name a few. Aim of this paper is to make the researchers aware of the various test case generation tools and techniques introduced in the last 11 years with their salient features

    Development of an Event Management Web Application For Students: A Focus on Back-end

    Get PDF
    Managing schedules can be challenging for students, with different calendars on various platforms leading to confusion and missed events. To address this problem, this thesis presents the development of an event management website designed to help students stay organized and motivated. With a focus on the application's back-end, this thesis explores the technology stack used to build the website and the implementation details of each chosen technology. By providing a detailed case study of the website development process, this thesis serves as a helpful resource for future developers looking to build their web applications

    Mapping the Focal Points of WordPress: A Software and Critical Code Analysis

    Get PDF
    Programming languages or code can be examined through numerous analytical lenses. This project is a critical analysis of WordPress, a prevalent web content management system, applying four modes of inquiry. The project draws on theoretical perspectives and areas of study in media, software, platforms, code, language, and power structures. The applied research is based on Critical Code Studies, an interdisciplinary field of study that holds the potential as a theoretical lens and methodological toolkit to understand computational code beyond its function. The project begins with a critical code analysis of WordPress, examining its origins and source code and mapping selected vulnerabilities. An examination of the influence of digital and computational thinking follows this. The work also explores the intersection of code patching and vulnerability management and how code shapes our sense of control, trust, and empathy, ultimately arguing that a rhetorical-cultural lens can be used to better understand code\u27s controlling influence. Recurring themes throughout these analyses and observations are the connections to power and vulnerability in WordPress\u27 code and how cultural, processual, rhetorical, and ethical implications can be expressed through its code, creating a particular worldview. Code\u27s emergent properties help illustrate how human values and practices (e.g., empathy, aesthetics, language, and trust) become encoded in software design and how people perceive the software through its worldview. These connected analyses reveal cultural, processual, and vulnerability focal points and the influence these entanglements have concerning WordPress as code, software, and platform. WordPress is a complex sociotechnical platform worthy of further study, as is the interdisciplinary merging of theoretical perspectives and disciplines to critically examine code. Ultimately, this project helps further enrich the field by introducing focal points in code, examining sociocultural phenomena within the code, and offering techniques to apply critical code methods
    corecore