3,309 research outputs found
An Ontological Approach to Representing the Product Life Cycle
The ability to access and share data is key to optimizing and streamlining any industrial production process. Unfortunately, the manufacturing industry is stymied by a lack of interoperability among the systems by which data are produced and managed, and this is true both within and across organizations. In this paper, we describe our work to address this problem through the creation of a suite of modular ontologies representing the product life cycle and its successive phases, from design to end of life. We call this suite the Product Life Cycle (PLC) Ontologies. The suite extends proximately from The Common Core Ontologies (CCO) used widely in defense and intelligence circles, and ultimately from the Basic Formal Ontology (BFO), which serves as top level ontology for the CCO and for some 300 further ontologies. The PLC Ontologies were developed together, but they have been factored to cover particular domains such as design, manufacturing processes, and tools. We argue that these ontologies, when used together with standard public domain alignment and browsing tools created within the context of the Semantic Web, may offer a low-cost approach to solving increasingly costly problems of data management in the manufacturing industry
Survey on Additive Manufacturing, Cloud 3D Printing and Services
Cloud Manufacturing (CM) is the concept of using manufacturing resources in a
service oriented way over the Internet. Recent developments in Additive
Manufacturing (AM) are making it possible to utilise resources ad-hoc as
replacement for traditional manufacturing resources in case of spontaneous
problems in the established manufacturing processes. In order to be of use in
these scenarios the AM resources must adhere to a strict principle of
transparency and service composition in adherence to the Cloud Computing (CC)
paradigm. With this review we provide an overview over CM, AM and relevant
domains as well as present the historical development of scientific research in
these fields, starting from 2002. Part of this work is also a meta-review on
the domain to further detail its development and structure
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SUPPORTING ENGINEERING DESIGN OF ADDITIVELY MANUFACTURED MEDICAL DEVICES WITH KNOWLEDGE MANAGEMENT THROUGH ONTOLOGIES
Medical environments pose a substantial challenge for engineering designers. They combine significant knowledge demands with large investment for new product development and severe consequences in the case of design failure. Engineering designers must contend with an often-chaotic environment to which they have limited access and familiarity, a user base that is difficult to engage and highly diverse in many attributes, and a market structure that often pits stakeholders against one another. As medical care in general moves towards personalized models and surgical tools towards less invasive options emerging manufacturing technologies in additive manufacturing offer significant potential for the design of highly innovative medical devices. At the same time however these same technologies also introduce yet more challenges to the design process.
This dissertation presents a knowledge-based approach to addressing the existing and emerging challenges of medical device design. The approach aims to address these challenges using knowledge captured in a suite of modular ontologies modeling knowledge domains that must be considered in medical device design. These include ontologies for understanding clinical context, human factors, regulation, enterprise, and manufacturability. Together these ontologies support design ideation, knowledge capture, and design verification. These ontologies are subsequently used to formulate a comprehensive knowledge framework for medical device design, and to enable an innovative design process. Case studies analyzing the design of surgical tools in several medical specialties are used to assess the capabilities of this approach
A review of composite product data interoperability and product life-cycle management challenges in the composites industry
A review of composite product data interoperability and product life-cycle management challenges is presented, which addresses âProduct Life-cycle Managementâ, developments in materials. The urgent need for this is illustrated by the life-cycle management issues faced in modern military aircraft, where in-service failure of composite parts is a problem, not just in terms of engineering understanding, but also in terms of the process for managing and maintaining the fleet. A demonstration of the use of ISO 10303-235 for a range of through-life composite product data is reported. The standardization of the digital representation of data can help businesses to automate data processing. With the development of new materials, the requirements for data information models for materials properties are evolving, and standardization drives transparency, improves the efficiency of data analysis, and enhances data accuracy. Current developments in Information Technology, such as big data analytics methodologies, have the potential to be highly transformative
Continuous maintenance and the future â Foundations and technological challenges
High value and long life products require continuous maintenance throughout their life cycle to achieve required performance with optimum through-life cost. This paper presents foundations and technologies required to offer the maintenance service. Component and system level degradation science, assessment and modelling along with life cycle âbig dataâ analytics are the two most important knowledge and skill base required for the continuous maintenance. Advanced computing and visualisation technologies will improve efficiency of the maintenance and reduce through-life cost of the product. Future of continuous maintenance within the Industry 4.0 context also identifies the role of IoT, standards and cyber security
Integration of e-business strategy for multi-lifecycle production systems
Internet use has grown exponentially on the last few years becoming a global communication and business resource. Internet-based business, or e-Business will truly affect every sector of the economy in ways that today we can only imagine. The manufacturing sector will be at the forefront of this change. This doctoral dissertation provides a scientific framework and a set of novel decision support tools for evaluating, modeling, and optimizing the overall performance of e-Business integrated multi-lifecycle production systems. The characteristics of this framework include environmental lifecycle study, environmental performance metrics, hyper-network model of integrated e-supply chain networks, fuzzy multi-objective optimization method, discrete-event simulation approach, and scalable enterprise environmental management system design. The dissertation research reveals that integration of e-Business strategy into production systems can alter current industry practices along a pathway towards sustainability, enhancing resource productivity, improving cost efficiencies and reducing lifecycle environmental impacts.
The following research challenges and scholarly accomplishments have been addressed in this dissertation: Identification and analysis of environmental impacts of e-Business. A pioneering environmental lifecycle study on the impact of e-Business is conducted, and fuzzy decision theory is further applied to evaluate e-Business scenarios in order to overcome data uncertainty and information gaps; Understanding, evaluation, and development of environmental performance metrics. Major environmental performance metrics are compared and evaluated. A universal target-based performance metric, developed jointly with a team of industry and university researchers, is evaluated, implemented, and utilized in the methodology framework; Generic framework of integrated e-supply chain network. The framework is based on the most recent research on large complex supply chain network model, but extended to integrate demanufacturers, recyclers, and resellers as supply chain partners. Moreover, The e-Business information network is modeled as a overlaid hypernetwork layer for the supply chain; Fuzzy multi-objective optimization theory and discrete-event simulation methods. The solution methods deal with overall system parameter trade-offs, partner selections, and sustainable decision-making; Architecture design for scalable enterprise environmental management system. This novel system is designed and deployed using knowledge-based ontology theory, and XML techniques within an agent-based structure. The implementation model and system prototype are also provided.
The new methodology and framework have the potential of being widely used in system analysis, design and implementation of e-Business enabled engineering systems
Development and characterisation of MSC-seeded decellularised airway scaffolds for regenerative bioengineering
Tracheal tissue engineering (TE) is a potential solution for long tracheal lesions and recent clinical experience yielded promising results but challenges remain with respect to measurable criteria for acceptance of decellularised scaffolds, optimisation of cell seeding and understanding the biology of the seeded cells post attachment. Confirming previous data from our group, I showed cellular clearance of DC scaffolds and significant reduction in total DNA levels but observed retention of residual nuclear materials within hyaline cartilage and submucosa. Evaluation of extracellular matrix components demonstrated retention of collagen and glycosaminoglycan and disrupted basement membrane components. The novel use of dynamic mechanical analysis (DMA) to measure the viscoelastic properties of tracheal cartilage in addition to tensile testing, provided the first demonstration of preservation of native viscoelastic mechanical properties after decellularisation. To overcome the limitations of passive cell seeding, I conceived partial surface dehydration (PSD) conditioning of scaffolds which significantly improved cell seeding/attachment efficiency to (96.46% 1.710) and I confirmed survival of MSCs on the scaffold in vitro. Multiphoton imaging showed limited scaffold infiltration but revealed two, distinct cell morphologies dependent on the presence or absence of adventitia. These showed different RNA transcriptomic profiles and differential gene expression. Seeded MSCs upregulated transcripts of bioactive paracrine factors associated with tissue repair, including ECM remodelling, pro-angiogenesis, antifibrosis, chemoattraction and immunomodulatory properties. Cells seeded into the adventitial layer upregulated more bioactive factors and showed lower cellular stress, suggesting a favourable effect of maintaining adventitial layer. The data presented herein form a coherent series of experiments providing novel data to the field of tracheal tissue engineering which address important GMP issues such as in-process acceptance criteria for scaffolds and data to support the rationale of autologous MSC seeding prior to implantation. These results allowed us to manufacture an improved clinical product for a compassionate case
Capturing design process information and rationale to support knowledge-based design and analysis integration
Issued as final reportUnited States. Dept. of Commerc
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