20,483 research outputs found
Machine Learning and Integrative Analysis of Biomedical Big Data.
Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues
Group-level Emotion Recognition using Transfer Learning from Face Identification
In this paper, we describe our algorithmic approach, which was used for
submissions in the fifth Emotion Recognition in the Wild (EmotiW 2017)
group-level emotion recognition sub-challenge. We extracted feature vectors of
detected faces using the Convolutional Neural Network trained for face
identification task, rather than traditional pre-training on emotion
recognition problems. In the final pipeline an ensemble of Random Forest
classifiers was learned to predict emotion score using available training set.
In case when the faces have not been detected, one member of our ensemble
extracts features from the whole image. During our experimental study, the
proposed approach showed the lowest error rate when compared to other explored
techniques. In particular, we achieved 75.4% accuracy on the validation data,
which is 20% higher than the handcrafted feature-based baseline. The source
code using Keras framework is publicly available.Comment: 5 pages, 3 figures, accepted for publication at ICMI17 (EmotiW Grand
Challenge
Building Combined Classifiers
This chapter covers different approaches that may be taken when building an
ensemble method, through studying specific examples of each approach from research
conducted by the authors. A method called Negative Correlation Learning illustrates a
decision level combination approach with individual classifiers trained co-operatively. The
Model level combination paradigm is illustrated via a tree combination method. Finally,
another variant of the decision level paradigm, with individuals trained independently
instead of co-operatively, is discussed as applied to churn prediction in the
telecommunications industry
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