Small-quantity lipid-based nutrient supplements, regardless of their zinc content, increase growth and reduce the prevalence of stunting and wasting in young Burkinabe children : a cluster-randomized trial

Small-quantity lipid-based nutrient supplements (SQ-LNS) are promising home fortification products, but the optimal zinc level needed to improve growth and reduce morbidity is uncertain. We aimed to assess the impact of providing SQ-LNS with varied amounts of zinc, along with illness treatment, on zinc-related outcomes compared with standard care. In a placebo-controlled, cluster-randomized trial, 34 communities were stratified to intervention (IC) or nonintervention cohorts (NIC). 2435 eligible IC children were randomly assigned to one of four groups: 1) SQ-LNS without zinc, placebo tablet; 2) SQ-LNS containing 5mg zinc, placebo tablet; 3) SQ-LNS containing 10mg zinc, placebo tablet; or 4) SQ-LNS without zinc and 5mg zinc tablet from 9-18 months of age. During weekly morbidity surveillance, oral rehydration salts were provided for reported diarrhea and antimalarial therapy for confirmed malaria. Children in NIC (n = 785) did not receive SQ-LNS, tablets, illness surveillance or treatment. At 9 and 18 months, length, weight and hemoglobin were measured in all children. Reported adherence was 97 +/- 6% for SQ-LNS and tablets. Mean baseline hemoglobin was 89 +/- 15g/L. At 18 months, change in hemoglobin was greater in IC than NIC (+8 vs -1g/L, p<0.0001), but 79.1% of IC were still anemic (vs. 91.1% in NIC). Final plasma zinc concentration did not differ by group. During the 9-month observation period, the incidence of diarrhea was 1.10 +/- 1.03 and of malaria 0.54 +/- 0.50 episodes per 100 child-days, and did not differ by group. Length at 18 months was significantly greater in IC compared to NIC (77.7 +/- 3.0 vs. 76.9 +/- 3.4cm; p<0.001) and stunting prevalence was significantly lower in IC (29.3%) than NIC (39.3%; p<0.0001), but did not differ by intervention group within IC. Wasting prevalence was also significantly lower in IC (8.7%) than in NIC (13.5%; p = 0.0003). Providing SQ-LNS daily with or without zinc, along with malaria and diarrhea treatment, significantly increased growth and reduced stunting, wasting and anemia prevalence in young children

Converting Europe - the potential for organic farming as mainstream

Organic farming is increasingly recognised, by consumers, farmers, environmentalists and policy-makers, as one of a number of possible models for environmental, social and financial sustainability in agriculture. It has taken a long time to get this far. Organic farming’s roots can be traced back more than 100 years. Certified organic production dates back 25-30 years (70 years in the case of Demeter-certified bio-dynamic production). Yet little more than one percent of agriculture in Europe is organic, and much less than that in other parts of the world. Many have argued that organic farming will never capture the hearts and minds of the majority of farmers, because it is too idealistic and restrictive. What is needed, they argue, is an intermediate approach, such as integrated crop management or an ill-specified ‘low-input’ or ‘sustainable’ agriculture that is not as ‘extreme’ as organic farming and is therefore more likely to be acceptable to the majority of farmers. Policy-makers face a difficult choice. Should they encourage more organic farming, which, as research increasingly demonstrates, often offers more environmental and other benefits than the intermediate approaches, but is believed to be only a minority interest? Or should they encourage the intermediate approaches, which, although the environmental benefits are more limited, may be adopted by more farmers, with possibly greater overall impact? And if, contrary to expectations, organic farming did become widely adopted, how could we feed a growing global population? It is time to dispel the myths and challenge the assumptions behind some of these statements in order to permit a fairer assessment of the potential of organic farming to meet sustainability goals in a European context, while also contributing to the pressing need to feed a growing global population in the next century. This paper discuses the growth of organic farming in Europe, and the potential, pre-conditions and implications for widespread conversion

The Segregated Lambda-coalescent

We construct an extension of the Lambda-coalescent to a spatial continuum and analyse its behaviour. Like the Lambda-coalescent, the individuals in our model can be separated into (i) a dust component and (ii) large blocks of coalesced individuals. We identify a five phase system, where our phases are defined according to changes in the qualitative behaviour of the dust and large blocks. We completely classify the phase behaviour, including necessary and sufficient conditions for the model to come down from infinity. We believe that two of our phases are new to Lambda-coalescent theory and directly reflect the incorporation of space into our model. Firstly, our semicritical phase sees a null but non-empty set of dust. In this phase the dust becomes a random fractal, of a type which is closely related to iterated function systems. Secondly, our model has a critical phase in which the coalescent comes down from infinity gradually during a bounded, deterministic time interval.Comment: Updated to accepted article - to appear in the Annals of Probability. 36 pages, 2 figure

Compact Drawings of 1-Planar Graphs with Right-Angle Crossings and Few Bends

We study the following classes of beyond-planar graphs: 1-planar, IC-planar, and NIC-planar graphs. These are the graphs that admit a 1-planar, IC-planar, and NIC-planar drawing, respectively. A drawing of a graph is 1-planar if every edge is crossed at most once. A 1-planar drawing is IC-planar if no two pairs of crossing edges share a vertex. A 1-planar drawing is NIC-planar if no two pairs of crossing edges share two vertices. We study the relations of these beyond-planar graph classes (beyond-planar graphs is a collective term for the primary attempts to generalize the planar graphs) to right-angle crossing (RAC) graphs that admit compact drawings on the grid with few bends. We present four drawing algorithms that preserve the given embeddings. First, we show that every $n$-vertex NIC-planar graph admits a NIC-planar RAC drawing with at most one bend per edge on a grid of size $O(n) \times O(n)$. Then, we show that every $n$-vertex 1-planar graph admits a 1-planar RAC drawing with at most two bends per edge on a grid of size $O(n^3) \times O(n^3)$. Finally, we make two known algorithms embedding-preserving; for drawing 1-planar RAC graphs with at most one bend per edge and for drawing IC-planar RAC graphs straight-line