Multi-Label ECG Classification using Temporal Convolutional Neural Network

Automated analysis of 12-lead electrocardiogram (ECG) plays a crucial role in the early screening and management of cardiovascular diseases (CVDs). In practice, it is common to see multiple co-occurring cardiac disorders, i.e., multi-label or multimorbidity in patients with CVDs, which increases the risk for mortality. Most current research focuses on the single-label ECG classification, i.e., each ECG record corresponds to one cardiac disorder, ignoring ECG records with multi-label phenomenon. In this paper, we propose an ensemble of attention-based temporal convolutional neural network (ATCNN) models for the multi-label classification of 12-lead ECG records. Specifically, a set of ATCNN-based single-lead binary classifiers are trained one for each cardiac disorder, and the predictions from these classifiers with simple thresholding generate the final multi-label decisions. The ATCNN contains a stack of TCNN layers followed by temporal and spatial attention layers. The TCNN layers operate at different dilation rates to represent the multi-scaled pathological ECG features dynamics, and attention layers emphasize/reduce the diagnostically relevant/redundant 12-lead ECG information. The proposed framework is evaluated on the PTBXL-2020 dataset and achieved an average F1-score of 76.51%. Moreover, the spatial and temporal attention weights visualization provides the optimal ECG-lead subset selection for each disease and model interpretability results, respectively. The improved performance and interpretability of the proposed approach demonstrate its ability to screen multimorbidity patients and help clinicians initiate timely treatment.Comment: Under review for publication in the IEEE Journal (8 pages, 6 figures

A Context-Responsive LSTM based IoT Enabled E- Healthcare Monitoring System for Arrhythmia Detection

Detecting Arrhythmia, a life-threatening cardiac condition, in real-time is crucial for timely intervention and improved healthcare outcomes. Traditional manual methods for Arrhythmia detection using Electrocardiogram (ECG) signals are error-prone and resource-intensive. To address these limitations, this paper presents an automated system based on the Context Responsive Long Short-Term Memory (CR-LSTM) model for real-time Arrhythmia classification. The system leverages IoT technology to continuously monitor vital signs and effectively combines contextual information with temporal sensor data to accurately discern different types of Arrhythmias. The CR-LSTM model achieves an impressive accuracy of 99.72% in multiclass classification of Arrhythmias, making it a promising solution for dynamic healthcare settings and proactive personalized care

A Compact LSTM-SVM Fusion Model for Long-Duration Cardiovascular Diseases Detection

Globally, cardiovascular diseases (CVDs) are the leading cause of mortality, accounting for an estimated 17.9 million deaths annually. One critical clinical objective is the early detection of CVDs using electrocardiogram (ECG) data, an area that has received significant attention from the research community. Recent advancements based on machine learning and deep learning have achieved great progress in this domain. However, existing methodologies exhibit inherent limitations, including inappropriate model evaluations and instances of data leakage. In this study, we present a streamlined workflow paradigm for preprocessing ECG signals into consistent 10-second durations, eliminating the need for manual feature extraction/beat detection. We also propose a hybrid model of Long Short-Term Memory (LSTM) with Support Vector Machine (SVM) for fraud detection. This architecture consists of two LSTM layers and an SVM classifier, which achieves a SOTA results with an Average precision score of 0.9402 on the MIT-BIH arrhythmia dataset and 0.9563 on the MIT-BIH atrial fibrillation dataset. Based on the results, we believe our method can significantly benefit the early detection and management of CVDs

TSFEDL: A python library for time series spatio-temporal feature extraction and prediction using deep learning

The combination of convolutional and recurrent neural networks is a promising framework. This arrangement allows the extraction of high-quality spatio-temporal features together with their temporal dependencies. This fact is key for time series prediction problems such as forecasting, classification or anomaly detection, amongst others. In this paper, the TSFEDL library is introduced. It compiles 22 state-of-the-art methods for both time series feature extraction and prediction, employing convolutional and recurrent deep neural networks for its use in several data mining tasks. The library is built upon a set of Tensorflow + Keras and PyTorch modules under the AGPLv3 license. The performance validation of the architectures included in this proposal confirms the usefulness of this Python package.This work has been partially supported by the Contract UGRAM OTRI-4260 and the Regional Government of Andalusia, under the program ‘‘Personal Investigador Doctor”, reference DOC_00235. This work was also supported by project PID2020-119478 GB-I00 granted by Ministerio de Ciencia, Innovación y Universidades, and projects P18-FR-4961 and P18-FR-4262 by Proyectos I + D+i Junta de Andalucia 2018

Heartbeat classification and arrhythmia detection using a multi-model deep-learning technique

Cardiac arrhythmias pose a significant danger to human life; therefore, it is of utmost importance to be able to efficiently diagnose these arrhythmias promptly. There exist many techniques for the detection of arrhythmias; however, the most widely adopted method is the use of an Electrocardiogram (ECG). The manual analysis of ECGs by medical experts is often inefficient. Therefore, the detection and recognition of ECG characteristics via machine-learning techniques have become prevalent. There are two major drawbacks of existing machine-learning approaches: (a) they require extensive training time; and (b) they require manual feature selection. To address these issues, this paper presents a novel deep-learning framework that integrates various networks by stacking similar layers in each network to produce a single robust model. The proposed framework has been tested on two publicly available datasets for the recognition of five micro-classes of arrhythmias. The overall classification sensitivity, specificity, positive predictive value, and accuracy of the proposed approach are 98.37%, 99.59%, 98.41%, and 99.35%, respectively. The results are compared with state-of-the-art approaches. The proposed approach outperformed the existing approaches in terms of sensitivity, specificity, positive predictive value, accuracy and computational cost

Detection and Localization of Myocardial Infarction Based on Multi-Scale ResNet and Attention Mechanism

PURPOSE: Myocardial infarction (MI) is one of the most common cardiovascular diseases, frequently resulting in death. Early and accurate diagnosis is therefore important, and the electrocardiogram (ECG) is a simple and effective method for achieving this. However, it requires assessment by a specialist; so many recent works have focused on the automatic assessment of ECG signals. METHODS: For the detection and localization of MI, deep learning models have been proposed, but the diagnostic accuracy of this approaches still need to be improved. Moreover, with deep learning methods the way in which a given result was achieved lacks interpretability. In this study, ECG data was obtained from the PhysioBank open access database, and was analyzed as follows. Firstly, the 12-lead ECG signal was preprocessed to identify each beat and obtain each heart interval. Secondly, a multi-scale deep learning model combined with a residual network and attention mechanism was proposed, where the input was the 12-lead ECG recording. Through the SENet model and the Grad-CAM algorithm, the weighting of each lead was calculated and visualized. Using existing knowledge of the way in which different types of MI gave characteristic patterns in specific ECG leads, the model was used to provisionally diagnose the type of MI according to the characteristics of each of the 12 ECG leads. RESULTS: Ten types of MI anterior, anterior lateral, anterior septal, inferior, inferior lateral, inferior posterior, inferior posterior lateral, lateral, posterior, and posterior lateral were diagnosed. The average accuracy, sensitivity, and specificity for MI detection of all lesion types was 99.98, 99.94, and 99.98%, respectively; and the average accuracy, sensitivity, and specificity for MI localization was 99.79, 99.88, and 99.98%, respectively. CONCLUSION: When compared to existing models based on traditional machine learning methods, convolutional neural networks and recurrent neural networks, the results showed that the proposed model had better diagnostic performance, being superior in accuracy, sensitivity, and specificity

Convolutional Neural Networks for Mechanistic Driver Detection in Atrial Fibrillation

The maintaining and initiating mechanisms of atrial fibrillation (AF) remain controversial. Deep learning is emerging as a powerful tool to better understand AF and improve its treatment, which remains suboptimal. This paper aims to provide a solution to automatically identify rotational activity drivers in endocardial electrograms (EGMs) with convolutional recurrent neural networks (CRNNs). The CRNN model was compared with two other state-of-the-art methods (SimpleCNN and attention-based time-incremental convolutional neural network (ATI-CNN)) for different input signals (unipolar EGMs, bipolar EGMs, and unipolar local activation times), sampling frequencies, and signal lengths. The proposed CRNN obtained a detection score based on the Matthews correlation coefficient of 0.680, an ATI-CNN score of 0.401, and a SimpleCNN score of 0.118, with bipolar EGMs as input signals exhibiting better overall performance. In terms of signal length and sampling frequency, no significant differences were found. The proposed architecture opens the way for new ablation strategies and driver detection methods to better understand the AF problem and its treatment