Robotic System Development for Precision MRI-Guided Needle-Based Interventions

This dissertation describes the development of a methodology for implementing robotic systems for interventional procedures under intraoperative Magnetic Resonance Imaging (MRI) guidance. MRI is an ideal imaging modality for surgical guidance of diagnostic and therapeutic procedures, thanks to its ability to perform high resolution, real-time, and high soft tissue contrast imaging without ionizing radiation. However, the strong magnetic field and sensitivity to radio frequency signals, as well as tightly confined scanner bore render great challenges to developing robotic systems within MRI environment. Discussed are potential solutions to address engineering topics related to development of MRI-compatible electro-mechanical systems and modeling of steerable needle interventions. A robotic framework is developed based on a modular design approach, supporting varying MRI-guided interventional procedures, with stereotactic neurosurgery and prostate cancer therapy as two driving exemplary applications. A piezoelectrically actuated electro-mechanical system is designed to provide precise needle placement in the bore of the scanner under interactive MRI-guidance, while overcoming the challenges inherent to MRI-guided procedures. This work presents the development of the robotic system in the aspects of requirements definition, clinical work flow development, mechanism optimization, control system design and experimental evaluation. A steerable needle is beneficial for interventional procedures with its capability to produce curved path, avoiding anatomical obstacles or compensating for needle placement errors. Two kinds of steerable needles are discussed, i.e. asymmetric-tip needle and concentric-tube cannula. A novel Gaussian-based ContinUous Rotation and Variable-curvature (CURV) model is proposed to steer asymmetric-tip needle, which enables variable curvature of the needle trajectory with independent control of needle rotation and insertion. While concentric-tube cannula is suitable for clinical applications where a curved trajectory is needed without relying on tissue interaction force. This dissertation addresses fundamental challenges in developing and deploying MRI-compatible robotic systems, and enables the technologies for MRI-guided needle-based interventions. This study applied and evaluated these techniques to a system for prostate biopsy that is currently in clinical trials, developed a neurosurgery robot prototype for interstitial thermal therapy of brain cancer under MRI guidance, and demonstrated needle steering using both asymmetric tip and pre-bent concentric-tube cannula approaches on a testbed

Planning Framework for Robotic Pizza Dough Stretching with a Rolling Pin

Stretching a pizza dough with a rolling pin is a nonprehensile manipulation. Since the object is deformable, force closure cannot be established, and the manipulation is carried out in a nonprehensile way. The framework of this pizza dough stretching application that is explained in this chapter consists of four sub-procedures: (i) recognition of the pizza dough on a plate, (ii) planning the necessary steps to shape the pizza dough to the desired form, (iii) path generation for a rolling pin to execute the output of the pizza dough planner, and (iv) inverse kinematics for the bi-manual robot to grasp and control the rolling pin properly. Using the deformable object model described in Chap. 3, each sub-procedure of the proposed framework is explained sequentially

Control of Real Mobile Robot Using Artificial Intelligence Technique

An eventual objective of mobile robotics research is to bestow the robot with high cerebral skill, of which navigation in an unfamiliar environment can be succeeded by using on‐line sensory information, which is essentially starved of humanoid intermediation. This research emphases on mechanical design of real mobile robot, its kinematic & dynamic model analysis and selection of AI technique based on perception, cognition, sensor fusion, path scheduling and analysis, which has to be implemented in robot for achieving integration of different preliminary robotic behaviors (e.g. obstacle avoidance, wall and edge following, escaping dead end and target seeking). Navigational paths as well as time taken during navigation by the mobile robot can be expressed as an optimization problem and thus can be analyzed and solved using AI techniques. The optimization of path as well as time taken is based on the kinematic stability and the intelligence of the robot controller. A set of linguistic fuzzy rules are developed to implement expert knowledge under various situations. Both of Mamdani and Takagi-Sugeno fuzzy model are employed in control algorithm for experimental purpose. Neural network has also been used to enhance and optimize the outcome of controller, e.g. by introducing a learning ability. The cohesive framework combining both fuzzy inference system and neural network enabled mobile robot to generate reasonable trajectories towards the target. An authenticity checking has been done by performing simulation as well as experimental results which showed that the mobile robot is capable of avoiding stationary obstacles, escaping traps, and reaching the goal efficiently

Design and Development of an Automated Mobile Manipulator for Industrial Applications

This thesis presents the modeling, control and coordination of an automated mobile manipulator. A mobile manipulator in this investigation consists of a robotic manipulator and a mobile platform resulting in a hybrid mechanism that includes a mobile platform for locomotion and a manipulator arm for manipulation. The structural complexity of a mobile manipulator is the main challenging issue because it includes several problems like adapting a manipulator and a redundancy mobile platform at non-holonomic constraints. The objective of the thesis is to fabricate an automated mobile manipulator and develop control algorithms that effectively coordinate the arm manipulation and mobility of mobile platform. The research work starts with deriving the motion equations of mobile manipulators. The derivation introduced here makes use of motion equations of robot manipulators and mobile platforms separately, and then integrated them as one entity. The kinematic analysis is performed in two ways namely forward & inverse kinematics. The motion analysis is performed for various WMPs such as, Omnidirectional WMP, Differential three WMP, Three wheeled omni-steer WMP, Tricycle WMP and Two steer WMP. From the obtained motion analysis results, Differential three WMP is chosen as the mobile platform for the developed mobile manipulator. Later motion analysis is carried out for 4-axis articulated arm. Danvit-Hartenberg representation is implemented to perform forward kinematic analysis. Because of this representation, one can easily understand the kinematic equation for a robotic arm. From the obtained arm equation, Inverse kinematic model for the 4-axis robotic manipulator is developed. Motion planning of an intelligent mobile robot is one of the most vital issues in the field of robotics, which includes the generation of optimal collision free trajectories within its work space and finally reaches its target position. For solving this problem, two evolutionary algorithms namely Particle Swarm Optimization (PSO) and Artificial Immune System (AIS) are introduced to move the mobile platform in intelligent manner. The developed algorithms are effective in avoiding obstacles, trap situations and generating optimal paths within its unknown environments. Once the robot reaches its goal (within the work space of the manipulator), the manipulator will generate its trajectories according to task assigned by the user. Simulation analyses are performed using MATLAB-2010 in order to validate the feasibility of the developed methodologies in various unknown environments. Additionally, experiments are carried out on an automated mobile manipulator. ATmega16 Microcontrollers are used to enable the entire robot system movement in desired trajectories by means of robot interface application program. The control program is developed in robot software (Keil) to control the mobile manipulator servomotors via a serial connection through a personal computer. To support the proposed control algorithms both simulation and experimental results are presented. Moreover, validation of the developed methodologies has been made with the ER-400 mobile platform

Design and analysis of Intelligent Navigational controller for Mobile Robot

Since last several years requirement graph for autonomous mobile robots according to its virtual application has always been an upward one. Smother and faster mobile robots navigation with multiple function are the necessity of the day. This research is based on navigation system as well as kinematics model analysis for autonomous mobile robot in known environments. To execute and attain introductory robotic behaviour inside environments(e.g. obstacle avoidance, wall or edge following and target seeking) robot uses method of perception, sensor integration and fusion. With the help of these sensors robot creates its collision free path and analyse an environmental map time to time. Mobile robot navigation in an unfamiliar environment can be successfully studied here using online sensor fusion and integration. Various AI algorithm are used to describe overall procedure of mobilerobot navigation and its path planning problem. To design suitable controller that create collision free path are achieved by the combined study of kinematics analysis of motion as well as an artificial intelligent technique. In fuzzy logic approach, a set of linguistic fuzzy rules are generated for navigation of mobile robot. An expert controller has been developed for the navigation in various condition of environment using these fuzzy rules. Further, type-2 fuzzy is employed to simplify and clarify the developed control algorithm more accurately due to fuzzy logic limitations. In addition, recurrent neural network (RNN) methodology has been analysed for robot navigation. Which helps the model at the time of learning stage. The robustness of controller has been checked on Webots simulation platform. Simulation results and performance of the controller using Webots platform show that, the mobile robot is capable for avoiding obstacles and reaching the termination point in efficient manner

Towards Closed-loop, Robot Assisted Percutaneous Interventions under MRI Guidance

Image guided therapy procedures under MRI guidance has been a focused research area over past decade. Also, over the last decade, various MRI guided robotic devices have been developed and used clinically for percutaneous interventions, such as prostate biopsy, brachytherapy, and tissue ablation. Though MRI provides better soft tissue contrast compared to Computed Tomography and Ultrasound, it poses various challenges like constrained space, less ergonomic patient access and limited material choices due to its high magnetic field. Even after, advancements in MRI compatible actuation methods and robotic devices using them, most MRI guided interventions are still open-loop in nature and relies on preoperative or intraoperative images. In this thesis, an intraoperative MRI guided robotic system for prostate biopsy comprising of an MRI compatible 4-DOF robotic manipulator, robot controller and control application with Clinical User Interface (CUI) and surgical planning applications (3DSlicer and RadVision) is presented. This system utilizes intraoperative images acquired after each full or partial needle insertion for needle tip localization. Presented system was approved by Institutional Review Board at Brigham and Women\u27s Hospital(BWH) and has been used in 30 patient trials. Successful translation of such a system utilizing intraoperative MR images motivated towards the development of a system architecture for close-loop, real-time MRI guided percutaneous interventions. Robot assisted, close-loop intervention could help in accurate positioning and localization of the therapy delivery instrument, improve physician and patient comfort and allow real-time therapy monitoring. Also, utilizing real-time MR images could allow correction of surgical instrument trajectory and controlled therapy delivery. Two of the applications validating the presented architecture; closed-loop needle steering and MRI guided brain tumor ablation are demonstrated under real-time MRI guidance

Vibration, Control and Stability of Dynamical Systems

From Preface: This is the fourteenth time when the conference “Dynamical Systems: Theory and Applications” gathers a numerous group of outstanding scientists and engineers, who deal with widely understood problems of theoretical and applied dynamics. Organization of the conference would not have been possible without a great effort of the staff of the Department of Automation, Biomechanics and Mechatronics. The patronage over the conference has been taken by the Committee of Mechanics of the Polish Academy of Sciences and Ministry of Science and Higher Education of Poland. It is a great pleasure that our invitation has been accepted by recording in the history of our conference number of people, including good colleagues and friends as well as a large group of researchers and scientists, who decided to participate in the conference for the first time. With proud and satisfaction we welcomed over 180 persons from 31 countries all over the world. They decided to share the results of their research and many years experiences in a discipline of dynamical systems by submitting many very interesting papers. This year, the DSTA Conference Proceedings were split into three volumes entitled “Dynamical Systems” with respective subtitles: Vibration, Control and Stability of Dynamical Systems; Mathematical and Numerical Aspects of Dynamical System Analysis and Engineering Dynamics and Life Sciences. Additionally, there will be also published two volumes of Springer Proceedings in Mathematics and Statistics entitled “Dynamical Systems in Theoretical Perspective” and “Dynamical Systems in Applications”

Indoor Navigation and Manipulation using a Segway RMP

This project dealt with a Segway RMP, utilizing it in an assistive-technology manner, encompassing navigation and manipulation aspects of robotics. First, background research was conducted to develop a blueprint for the robot. The hardware, software, and configuration of the RMP was updated, and a robotic arm was designed to extend the RMP’s capabilities. The robot was programmed to accomplish autonomous multi-floor navigation through the use of the navigation stack in ROS, image detection, and a GUI. The robot can navigate through the hallways of the building utilizing the elevator. The robotic arm was designed to accomplish tasks such as pressing a button and picking an object up off of a table. The Segway RMP is designed to be utilized and expanded upon as a robotics research platform

Nonlinear control and synchronization of multiple Lagrangian systems with application to tethered formation flight spacecraft

Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2007.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Includes bibliographical references (p. 217-228).This dissertation focuses on the synchronization of multiple dynamical systems using contraction theory, with applications to cooperative control of multi-agent systems and synchronization of interconnected dynamics such as tethered formation flight. Inspired by stable combinations of biological systems, contraction nonlinear stability theory provides a systematic method to reduce arbitrarily complex systems into simpler elements. One application of oscillation synchronization is a fully decentralized nonlinear control law, which eliminates the need for any inter-satellite communications. We use contraction theory to prove that a nonlinear control law stabilizing a single-tethered spacecraft can also stabilize arbitrarily large circular arrays of tethered spacecraft, as well as a three-spacecraft inline configuration. The convergence result is global and exponential due to the nature of contraction analysis. The proposed decentralized control strategy is further extended to robust adaptive control in order to account for model uncertainties. Numerical simulations and experimental results validate the exponential stability of the tethered formation arrays by implementing a tracking control law derived from the reduced dynamics.(cont.) This thesis also presents a new synchronization framework that can be directly applied to cooperative control of autonomous aerospace vehicles and oscillation synchronization in robotic manipulation and locomotion. We construct a dynamical network of multiple Lagrangian systems by adding diffusive couplings to otherwise freely moving or flying vehicles. The proposed tracking control law synchronizes an arbitrary number of robots into a common trajectory with global exponential convergence. The proposed control law is much simpler than earlier work in terms of both the computational load and the required signals. Furthermore, in contrast with earlier work which used simple double integrator models, the proposed method permits highly nonlinear systems and is further extended to adaptive synchronization, partial-joint coupling, and concurrent synchronization. Another contribution of the dissertation is a novel nonlinear control approach for underactuated tethered formation flight spacecraft. This is motivated by a controllability analysis that indicates that both array resizing and spin-up are fully controllable by the reaction wheels and the tether motor. This work reports the first propellant-free underactuated control results for tethered formation flight.(cont.) We also fulfill the potential of the proposed strategy by providing a new momentum dumping method. This dissertation work has evolved based on the research philosophy of balancing theoretical work with practicality, aiming at physically intuitive algorithms that can be directly implemented in real systems. In order to validate the effectiveness of the decentralized control and estimation framework, a new suite of hardware has been designed and added to the SPHERES (Synchronize Position Hold Engage and Reorient Experimental Satellite) testbed. Such recent improvements described in this dissertation include a new tether reel mechanism, a force-torque sensor and an air-bearing carriage with a reaction wheel. This thesis also introduces a novel relative attitude estimator, in which a series of Kalman filters incorporate the gyro, force-torque sensor and ultrasound ranging measurements. The closed-loop control experiments can be viewed at ...by Soon-Jo Chung.Sc.D

ReSCon '12, Research Student Conference: Book of Abstracts

The fifth SED Research Student Conference (ReSCon2012) was hosted over three days, 18-20 June 2012, in the Hamilton Centre at Brunel University. The conference consisted of 130 oral and 70 poster presentations, based on the high quality and diverse research being conducted within the School of Engineering and Design by postgraduate research students. The conference is held annually, and ReSCon plays a key role in contributing to research and innovations within the School