A MODEL FOR PREDICTION OF DRUG RESISTANT TUBERCULOSIS USING DATA MINING TECHNIQUE

The rate of mortality in the recent time because of tuberculosis disease is so alarming. Drug-Resistant Tuberculosis is a communicable disease very dangerous that attack lungs, many victims were not identified due to weak health systems facilities, poor doctor-patient relationship, and inefficient mechanisms for predicting of the disease. Data mining can be applied on medical data to foresee novel, useful and potential knowledge that can save a life, reduce treatment cost, increases diagnostic and prediction accuracy as well as delay taking during prediction which reduce the treatment cost of a patience. Several data mining technique such as classification, clustering, regression, and association rule were used to enhance the prediction of tuberculosis. In this project I used Naïve Bayes Classifier to design a model for predicting tuberculosis. I considered the following parameters; Gender, Chills, Fever, Night sweat, Fatigue, Cough with Blood, Weight loss, and Loss of Appetite for classification phase 1. While Gender Chest Pain, Sputum, Contact DR, Weight Loss, In-adequate treatment for classification phase 2 as the clinical symptom. The Naïve Bayes Classifier has the advantage of attribute independency, it is easy in construction, can classify categorical data, and can work on high dimensional data effectively. The model designed using Naïve Bayes Classifier is divided o into classification phase 1 and classification phase 2 and implemented using Phython 3.2 Programing Language. The result shows that Naïve Bayes Classfier was suitable in predicting drug resistant tuberculosis with performance accuracy of 82%, 98% and area under curve (AUC) is 88%. Keywords: Model Prediction, Tuberculosis. Drug, Resistant, Data Mining

Image mining: issues, frameworks and techniques

[Abstract]: Advances in image acquisition and storage technology have led to tremendous growth in significantly large and detailed image databases. These images, if analyzed, can reveal useful information to the human users. Image mining deals with the extraction of implicit knowledge, image data relationship, or other patterns not explicitly stored in the images. Image mining is more than just an extension of data mining to image domain. It is an interdisciplinary endeavor that draws upon expertise in computer vision, image processing, image retrieval, data mining, machine learning, database, and artificial intelligence. Despite the development of many applications and algorithms in the individual research fields cited above, research in image mining is still in its infancy. In this paper, we will examine the research issues in image mining, current developments in image mining, particularly, image mining frameworks, state-of-the-art techniques and systems. We will also identify some future research directions for image mining at the end of this paper

Application of an efficient Bayesian discretization method to biomedical data

Background\ud Several data mining methods require data that are discrete, and other methods often perform better with discrete data. We introduce an efficient Bayesian discretization (EBD) method for optimal discretization of variables that runs efficiently on high-dimensional biomedical datasets. The EBD method consists of two components, namely, a Bayesian score to evaluate discretizations and a dynamic programming search procedure to efficiently search the space of possible discretizations. We compared the performance of EBD to Fayyad and Irani's (FI) discretization method, which is commonly used for discretization.\ud \ud Results\ud On 24 biomedical datasets obtained from high-throughput transcriptomic and proteomic studies, the classification performances of the C4.5 classifier and the naïve Bayes classifier were statistically significantly better when the predictor variables were discretized using EBD over FI. EBD was statistically significantly more stable to the variability of the datasets than FI. However, EBD was less robust, though not statistically significantly so, than FI and produced slightly more complex discretizations than FI.\ud \ud Conclusions\ud On a range of biomedical datasets, a Bayesian discretization method (EBD) yielded better classification performance and stability but was less robust than the widely used FI discretization method. The EBD discretization method is easy to implement, permits the incorporation of prior knowledge and belief, and is sufficiently fast for application to high-dimensional data

Image mining: trends and developments

[Abstract]: Advances in image acquisition and storage technology have led to tremendous growth in very large and detailed image databases. These images, if analyzed, can reveal useful information to the human users. Image mining deals with the extraction of implicit knowledge, image data relationship, or other patterns not explicitly stored in the images. Image mining is more than just an extension of data mining to image domain. It is an interdisciplinary endeavor that draws upon expertise in computer vision, image processing, image retrieval, data mining, machine learning, database, and artificial intelligence. In this paper, we will examine the research issues in image mining, current developments in image mining, particularly, image mining frameworks, state-of-the-art techniques and systems. We will also identify some future research directions for image mining

An information-driven framework for image mining

[Abstract]: Image mining systems that can automatically extract semantically meaningful information (knowledge) from image data are increasingly in demand. The fundamental challenge in image mining is to determine how low-level, pixel representation contained in a raw image or image sequence can be processed to identify high-level spatial objects and relationships. To meet this challenge, we propose an efficient information-driven framework for image mining. We distinguish four levels of information: the Pixel Level, the Object Level, the Semantic Concept Level, and the Pattern and Knowledge Level. High-dimensional indexing schemes and retrieval techniques are also included in the framework to support the flow of information among the levels. We believe this framework represents the first step towards capturing the different levels of information present in image data and addressing the issues and challenges of discovering useful patterns/knowledge from each level

Evaluation of linear classifiers on articles containing pharmacokinetic evidence of drug-drug interactions

Background. Drug-drug interaction (DDI) is a major cause of morbidity and mortality. [...] Biomedical literature mining can aid DDI research by extracting relevant DDI signals from either the published literature or large clinical databases. However, though drug interaction is an ideal area for translational research, the inclusion of literature mining methodologies in DDI workflows is still very preliminary. One area that can benefit from literature mining is the automatic identification of a large number of potential DDIs, whose pharmacological mechanisms and clinical significance can then be studied via in vitro pharmacology and in populo pharmaco-epidemiology. Experiments. We implemented a set of classifiers for identifying published articles relevant to experimental pharmacokinetic DDI evidence. These documents are important for identifying causal mechanisms behind putative drug-drug interactions, an important step in the extraction of large numbers of potential DDIs. We evaluate performance of several linear classifiers on PubMed abstracts, under different feature transformation and dimensionality reduction methods. In addition, we investigate the performance benefits of including various publicly-available named entity recognition features, as well as a set of internally-developed pharmacokinetic dictionaries. Results. We found that several classifiers performed well in distinguishing relevant and irrelevant abstracts. We found that the combination of unigram and bigram textual features gave better performance than unigram features alone, and also that normalization transforms that adjusted for feature frequency and document length improved classification. For some classifiers, such as linear discriminant analysis (LDA), proper dimensionality reduction had a large impact on performance. Finally, the inclusion of NER features and dictionaries was found not to help classification.Comment: Pacific Symposium on Biocomputing, 201

Deep learning for time series classification: a review

Time Series Classification (TSC) is an important and challenging problem in data mining. With the increase of time series data availability, hundreds of TSC algorithms have been proposed. Among these methods, only a few have considered Deep Neural Networks (DNNs) to perform this task. This is surprising as deep learning has seen very successful applications in the last years. DNNs have indeed revolutionized the field of computer vision especially with the advent of novel deeper architectures such as Residual and Convolutional Neural Networks. Apart from images, sequential data such as text and audio can also be processed with DNNs to reach state-of-the-art performance for document classification and speech recognition. In this article, we study the current state-of-the-art performance of deep learning algorithms for TSC by presenting an empirical study of the most recent DNN architectures for TSC. We give an overview of the most successful deep learning applications in various time series domains under a unified taxonomy of DNNs for TSC. We also provide an open source deep learning framework to the TSC community where we implemented each of the compared approaches and evaluated them on a univariate TSC benchmark (the UCR/UEA archive) and 12 multivariate time series datasets. By training 8,730 deep learning models on 97 time series datasets, we propose the most exhaustive study of DNNs for TSC to date.Comment: Accepted at Data Mining and Knowledge Discover