Endoscopic optical coherence tomography with a flexible fiber bundle

We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope design by avoiding the integration of any beam steering components in the distal probe end due to 2D scanning of a focused light beam over the proximal fiber bundle surface. We describe the challenges that arise when OCT imaging with a fiber bundle is performed, such as multimoding or cross-coupling. The performance of different fiber bundles with varying parameters such as numerical aperture, core size and core structure was consequently compared and artifacts that degrade the image quality were described in detail. Based on our findings, we propose an optimal fiber bundle design for endoscopic OCT imaging

Electrically packaged silicon-organic hybrid (SOH) I/Q-modulator for 64 GBd operation

Silicon-organic hybrid (SOH) electro-optic (EO) modulators combine small footprint with low operating voltage and hence low power dissipation, thus lending themselves to on-chip integration of large-scale device arrays. Here we demonstrate an electrical packaging concept that enables high-density radio-frequency (RF) interfaces between on-chip SOH devices and external circuits. The concept combines high-resolution $\mathrm{Al_2O_3}$ printed-circuit boards with technically simple metal wire bonds and is amenable to packaging of device arrays with small on-chip bond pad pitches. In a set of experiments, we characterize the performance of the underlying RF building blocks and we demonstrate the viability of the overall concept by generation of high-speed optical communication signals. Achieving line rates (symbols rates) of 128 Gbit/s (64 GBd) using quadrature-phase-shiftkeying (QPSK) modulation and of 160 Gbit/s (40 GBd) using 16-state quadrature-amplitudemodulation (16QAM), we believe that our demonstration represents an important step in bringing SOH modulators from proof-of-concept experiments to deployment in commercial environments

Optomechanical transduction of an integrated silicon cantilever probe using a microdisk resonator

Sensitive transduction of the motion of a microscale cantilever is central to many applications in mass, force, magnetic resonance, and displacement sensing. Reducing cantilever size to nanoscale dimensions can improve the bandwidth and sensitivity of techniques like atomic force microscopy, but current optical transduction methods suffer when the cantilever is small compared to the achievable spot size. Here, we demonstrate sensitive optical transduction in a monolithic cavity-optomechanical system in which a sub-picogram silicon cantilever with a sharp probe tip is separated from a microdisk optical resonator by a nanoscale gap. High quality factor (Q ~ 10^5) microdisk optical modes transduce the cantilever's MHz frequency thermally-driven vibrations with a displacement sensitivity of ~ 4.4x10^-16 m\sqrt[2]{Hz} and bandwidth > 1 GHz, and a dynamic range > 10^6 is estimated for a 1 s measurement. Optically-induced stiffening due to the strong optomechanical interaction is observed, and engineering of probe dynamics through cantilever design and electrostatic actuation is illustrated

Design and Optimize a Two Color Fourier Domain Pump Probe Optical Coherence Tomography System

Molecular imaging using fluorescence spectroscopy-based techniques is generally inefficient due to the low quantum yield of most naturally occurring biomolecules. Current fluorescence imaging techniques tag these biomolecules chemically or through genetic manipulation, increasing the complexity of the system. A technique capable of imaging these biomolecules without modifying the chromophore and/or its environment could provide vital biometric parameters and unique insights into various biological processes at a molecular level. Pump probe spectroscopy has been used extensively to study the molecular properties of poorly fluorescing biomolecules, because it utilizes the known absorption spectrum of these chromophores. Optical Coherence Tomography (OCT) is an optical imaging modality that harnesses the power of low coherence interferometry to measure the 3-D spatially resolved reflectivity of a tissue sample. We plan to develop a new molecular imaging modality that combines these techniques to provide 3-D, highresolution molecular images of various important biomolecules. The system uses a Fourier domain OCT setup with a modified sample arm that combines the "pump" and "probe" beams. The pump beam drives the molecules from the ground state to excited state and the probe interrogates the population change due to the pump and is detected interferometrically. The pump and the probe beam wavelengths are optimized to maximize absorption at the pump wavelength and maximize the penetration depth at the probe wavelength. The pump-probe delay can be varied to measure the rate at which the excited state repopulates the ground state, i.e., the ground state recovery time. The ground state recovery time varies for different chromophores and can potentially be used to identify different biomolecules. The system was designed and optimized to increase the SNR of the PPOCT signals. It was tested by imaging hemoglobin and melanin samples and yielded encouraging results. Potential applications of imaging hemoglobin using this technique include the mapping of tissue microvasculature and measuring blood-oxygen saturation levels. These applications could be used to identify hypoxic areas in tissue. Melanin imaging can provide means of demarcation of melanoma in various organs such as skin, eye and intestines

LASER Tech Briefs, Spring 1994

Topics in this Laser Tech Brief include: Electronic Components and Circuits. Electronic Systems, Physical Sciences, Materials, Mechanics, Fabrication Technology, and books and reports

Hybrid integration methods for on-chip quantum photonics

The goal of integrated quantum photonics is to combine components for the generation, manipulation, and detection of nonclassical light in a phase-stable and efficient platform. Solid-state quantum emitters have recently reached outstanding performance as single-photon sources. In parallel, photonic integrated circuits have been advanced to the point that thousands of components can be controlled on a chip with high efficiency and phase stability. Consequently, researchers are now beginning to combine these leading quantum emitters and photonic integrated circuit platforms to realize the best properties of each technology. In this paper, we review recent advances in integrated quantum photonics based on such hybrid systems. Although hybrid integration solves many limitations of individual platforms, it also introduces new challenges that arise from interfacing different materials. We review various issues in solid-state quantum emitters and photonic integrated circuits, the hybrid integration techniques that bridge these two systems, and methods for chip-based manipulation of photons and emitters. Finally, we discuss the remaining challenges and future prospects of on-chip quantum photonics with integrated quantum emitters. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreemen

Spectral Interferometry with Frequency Combs

In this review paper, we provide an overview of the state of the art in linear interferometric techniques using laser frequency comb sources. Diverse techniques including Fourier transform spectroscopy, linear spectral interferometry and swept-wavelength interferometry are covered in detail. The unique features brought by laser frequency comb sources are shown, and specific applications highlighted in molecular spectroscopy, optical coherence tomography and the characterization of photonic integrated devices and components. Finally, the possibilities enabled by advances in chip scale swept sources and frequency combs are discussed