7,960 research outputs found
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The Epidemiology and Genetic Architecture of Vitamin D Deficiency in African Children
Vitamin D deficiency is a common public health problem worldwide. However, little is known about the epidemiology of vitamin D deficiency in Africa. In this thesis, I aimed to determine: 1) the prevalence of and risk factors associated with vitamin D deficiency in studies conducted in Africa; 2) the prevalence and predictors of vitamin D deficiency in African children; 3) the association between vitamin D and iron deficiency in African children; and 4) genetic variants that influence vitamin D status in Africans.
In a systematic review and meta-analyses of previous vitamin D studies in Africa, the average prevalence of low vitamin D status was 18.5%, 34.2% and 59.5% using cut-offs of 25-hydroxyvitamin D (25(OH)D) levels of <30 nmol/L, <50 nmol/L and <75 nmol/L, respectively. Populations at risk of vitamin D deficiency included newborns, women, and people living in high latitudes or urban areas.
In an epidemiological study of young children living in Africa, the prevalence of low vitamin D status was 0.6%, 7.8% and 44.5% using cut-offs of 25(OH)D levels of GC2 variant of the group-specific component (GC) gene, which encodes vitamin D binding protein.
Vitamin D deficiency was also associated with 80% higher odds of iron deficiency in these children. Adjusted regression models revealed that vitamin D deficiency was associated with higher ferritin and hepcidin levels suggesting lower iron status, and reduced sTfR and transferrin levels and increased TSAT and serum iron levels suggesting improved iron status.
Genome-wide association study (GWAS) in Africans revealed genetic variants that influence vitamin D status in vitamin D metabolism genes: DHCR7/NADSYN1, CYP2R1 and GC. However, the majority of SNPs from previous European GWASs did not replicate in the current GWAS.
Findings from this thesis indicate that vitamin D deficiency is prevalent in many African populations and should be considered in public health strategies in Africa
The determinants of value addition: a crtitical analysis of global software engineering industry in Sri Lanka
It was evident through the literature that the perceived value delivery of the global software
engineering industry is low due to various facts. Therefore, this research concerns global
software product companies in Sri Lanka to explore the software engineering methods and
practices in increasing the value addition. The overall aim of the study is to identify the key
determinants for value addition in the global software engineering industry and critically
evaluate the impact of them for the software product companies to help maximise the value
addition to ultimately assure the sustainability of the industry.
An exploratory research approach was used initially since findings would emerge while the
study unfolds. Mixed method was employed as the literature itself was inadequate to
investigate the problem effectively to formulate the research framework. Twenty-three face-to-face online interviews were conducted with the subject matter experts covering all the
disciplines from the targeted organisations which was combined with the literature findings as
well as the outcomes of the market research outcomes conducted by both government and nongovernment institutes. Data from the interviews were analysed using NVivo 12. The findings
of the existing literature were verified through the exploratory study and the outcomes were
used to formulate the questionnaire for the public survey. 371 responses were considered after
cleansing the total responses received for the data analysis through SPSS 21 with alpha level
0.05. Internal consistency test was done before the descriptive analysis. After assuring the
reliability of the dataset, the correlation test, multiple regression test and analysis of variance
(ANOVA) test were carried out to fulfil the requirements of meeting the research objectives.
Five determinants for value addition were identified along with the key themes for each area.
They are staffing, delivery process, use of tools, governance, and technology infrastructure.
The cross-functional and self-organised teams built around the value streams, employing a
properly interconnected software delivery process with the right governance in the delivery
pipelines, selection of tools and providing the right infrastructure increases the value delivery.
Moreover, the constraints for value addition are poor interconnection in the internal processes,
rigid functional hierarchies, inaccurate selections and uses of tools, inflexible team
arrangements and inadequate focus for the technology infrastructure. The findings add to the
existing body of knowledge on increasing the value addition by employing effective processes,
practices and tools and the impacts of inaccurate applications the same in the global software
engineering industry
TOWARDS AN UNDERSTANDING OF EFFORTFUL FUNDRAISING EXPERIENCES: USING INTERPRETATIVE PHENOMENOLOGICAL ANALYSIS IN FUNDRAISING RESEARCH
Physical-activity oriented community fundraising has experienced an exponential growth in popularity over the past 15 years. The aim of this study was to explore the value of effortful fundraising experiences, from the point of view of participants, and explore the impact that these experiences have on people’s lives. This study used an IPA approach to interview 23 individuals, recognising the role of participants as proxy (nonprofessional) fundraisers for charitable organisations, and the unique organisation donor dynamic that this creates. It also bought together relevant psychological theory related to physical activity fundraising experiences (through a narrative literature review) and used primary interview data to substantiate these. Effortful fundraising experiences are examined in detail to understand their significance to participants, and how such experiences influence their connection with a charity or cause. This was done with an idiographic focus at first, before examining convergences and divergences across the sample. This study found that effortful fundraising experiences can have a profound positive impact upon community fundraisers in both the short and the long term. Additionally, it found that these experiences can be opportunities for charitable organisations to create lasting meaningful relationships with participants, and foster mutually beneficial lifetime relationships with them. Further research is needed to test specific psychological theory in this context, including self-esteem theory, self determination theory, and the martyrdom effect (among others)
'Exarcheia doesn't exist': Authenticity, Resistance and Archival Politics in Athens
My thesis investigates the ways people, materialities and urban spaces interact to form affective ecologies and produce historicity. It focuses on the neighbourhood of Exarcheia, Athens’ contested political topography par excellence, known for its production of radical politics of discontent and resistance to state oppression and eoliberal capitalism. Embracing Exarcheia’s controversial status within Greek vernacular, media and state discourses, this thesis aims to unpick the neighbourhoods’ socio-spatial assemblage imbued with affect and formed through the numerous (mis)understandings and (mis)interpretations rooted in its turbulent political history. Drawing on theory on urban spaces, affect, hauntology and archival politics, I argue for Exarcheia as an unwavering archival space composed of affective chronotopes – (in)tangible loci that defy space and temporality. I posit that the interwoven narratives and materialities emerging in my fieldwork are persistently – and perhaps obsessively – reiterating themselves and remaining imprinted on the neighbourhood’s landscape as an incessant reminder of violent histories that the state often seeks to erase and forget. Through this analysis, I contribute to understandings of place as a primary ethnographic ‘object’ and the ways in which place forms complex interactions and relationships with social actors, shapes their subjectivities, retains and bestows their memories and senses of historicity
The Adirondack Chronology
The Adirondack Chronology is intended to be a useful resource for researchers and others interested in the Adirondacks and Adirondack history.https://digitalworks.union.edu/arlpublications/1000/thumbnail.jp
Investigating and mitigating the role of neutralisation techniques on information security policies violation in healthcare organisations
Healthcare organisations today rely heavily on Electronic Medical Records systems (EMRs), which have become highly crucial IT assets that require significant security efforts to safeguard patients’ information. Individuals who have legitimate access to an organisation’s assets to perform their day-to-day duties but intentionally or unintentionally violate information security policies can jeopardise their organisation’s information security efforts and cause significant legal and financial losses. In the information security (InfoSec) literature, several studies emphasised the necessity to understand why employees behave in ways that contradict information security requirements but have offered widely different solutions. In an effort to respond to this situation, this thesis addressed the gap in the information security academic research by providing a deep understanding of the problem of medical practitioners’ behavioural justifications to violate information security policies and then determining proper solutions to reduce this undesirable behaviour. Neutralisation theory was used as the theoretical basis for the research. This thesis adopted a mixed-method research approach that comprises four consecutive phases, and each phase represents a research study that was conducted in light of the results from the preceding phase. The first phase of the thesis started by investigating the relationship between medical practitioners’ neutralisation techniques and their intention to violate information security policies that protect a patient’s privacy. A quantitative study was conducted to extend the work of Siponen and Vance [1] through a study of the Saudi Arabia healthcare industry. The data was collected via an online questionnaire from 66 Medical Interns (MIs) working in four academic hospitals. The study found that six neutralisation techniques—(1) appeal to higher loyalties, (2) defence of necessity, (3) the metaphor of ledger, (4) denial of responsibility, (5) denial of injury, and (6) condemnation of condemners—significantly contribute to the justifications of the MIs in hypothetically violating information security policies. The second phase of this research used a series of semi-structured interviews with IT security professionals in one of the largest academic hospitals in Saudi Arabia to explore the environmental factors that motivated the medical practitioners to evoke various neutralisation techniques. The results revealed that social, organisational, and emotional factors all stimulated the behavioural justifications to breach information security policies. During these interviews, it became clear that the IT department needed to ensure that security policies fit the daily tasks of the medical practitioners by providing alternative solutions to ensure the effectiveness of those policies. Based on these interviews, the objective of the following two phases was to improve the effectiveness of InfoSec policies against the use of behavioural justification by engaging the end users in the modification of existing policies via a collaborative writing process. Those two phases were conducted in the UK and Saudi Arabia to determine whether the collaborative writing process could produce a more effective security policy that balanced the security requirements with daily business needs, thus leading to a reduction in the use of neutralisation techniques to violate security policies. The overall result confirmed that the involvement of the end users via a collaborative writing process positively improved the effectiveness of the security policy to mitigate the individual behavioural justifications, showing that the process is a promising one to enhance security compliance
Contemporary, decadal, and millennial-scale permafrost- and vegetation dynamics and carbon release in an alpine region of Jotunheimen, Norway
Climatic warming in northern alpine regions facilitates the thawing of permafrost, the associated release of soil carbon into the atmosphere, and the altitudinal shifts in vegetation patterns. Here, a multi-disciplinary approach is adopted to investigate the response of an alpine permafrost landscape (Jotunheimen, Norway, with focus on Galdhøpiggen) to climatic changes over long- to medium timescales. First, a gas analyser is used to explore how ecosystem respiration is affected by ecosystem (soil and vegetation) and geomorphological (cryogenic disturbance) factors during the peak growing season. A palaeoecological record is then analysed to infer the past dynamics of the alpine tree lines and the lower limit of permafrost on Galdhøpiggen over the millennial- and centennial scales. Finally, remotely sensed satellite imagery is combined with observed air temperatures to create a model that provides an estimation of land surface temperatures over the past six decades. The model is then used to predict surface ‘greenness’ over the same period. Palynological evidence from Galdhøpiggen indicates that the altitudinal limits of alpine tree lines have shifted by hundreds of metres in response to climatic changes over the millennial scale. Since 1957, the model predictions indicate substantial increases in land surface temperatures and growing season surface ‘greenness’ (i.e., vegetation abundance) in Jotunheimen, but the change has not been spatially uniform. The highest increases were recorded over the low- and mid-alpine heaths above the tree line (1050-1500 m a.s.l.), which was attributed to increased shrub cover. This trend could facilitate carbon release from the ground, as peak growing season ecosystem respiration was found to be most strongly controlled by soil microclimate and plant growth forms. The likely future scenario in response to warming in Jotunheimen will be continued permafrost degradation, with higher altitudes (≥1500 m a.s.l.) experiencing decreased cryoturbation, increased shrub encroachment and higher surface CO2 emissions
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Building Together: Problem Solving for Sustainability Consciousness
BUILDING TOGETHER:
PROBLEM SOLVING FOR SUSTAINABILITY CONSCIOUSNESS
FEBRUARY 2022
PAUL M. BOCKO, B.A., UNIVERSITY OF NEW HAMPSHIRE
M.S., ANTIOCH UNIVERSITY NEW ENGLAND
M.Ed. ANITOCH UNIVERSITY NEW ENGLAND
Ph.D., UNIVERSITY OF MASSACHUSETTS AMHERST
Directed by: Professor Linda Griffin
This case study examined the relationship of problem-based learning (PBL) and sustainability education in a combined fifth and sixth grade classroom in the northeast U.S. Research questions focused on PBL instructional strategies that promote sustainability education, skills and understandings promoted by PBL, and the extent that PBL affects students’ sustainability consciousness. One teacher and eleven students participated. Problem-posing, reconstructionist, and sociocultural theories framed the study. Relevant themes were identified in a review of sustainability consciousness (SC) and PreK-12 PBL research reports. The themes revealed that SC is a growing framework with which to assess sustainability education and PBL research has strong links with sustainability education learning outcomes. Survey, interview, artifact, and observational data were analyzed to understand the fifth and sixth grade class as a case study in sustainability education. Results include a learning environment that emphasizes a pedagogy of sustainable thinking, student exhibition of sustainability education skills and understandings, and a lack of quantitative evidence of growth in students’ SC contrasted
with evidence of SC in students’ written work. Findings affirmed prior PBL research focused on group collaboration, interdependency, and reflection. The study identified the need to study PBL in real-world contexts rather than only through problem scenarios. Contributions to knowledge include adding to PBL research literature, highlighting the importance of learning experiences designed to meet a school’s mission, and increasing the use of a new survey instrument.
Keywords: Sociocultural, reconstructionism, problem-based learning, wicked problems, sustainability education, scaffolding, collaboration, interdependency
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