Efficient Methods for Continuous and Discrete Shape Analysis

When interpreting an image of a given object, humans are able to abstract from the presented color information in order to really see the presented object. This abstraction is also known as shape. The concept of shape is not defined exactly in Computer Vision and in this work, we use three different forms of these definitions in order to acquire and analyze shapes. This work is devoted to improve the efficiency of methods that solve important applications of shape analysis. The most important problem in order to analyze shapes is the problem of shape acquisition. To simplify this very challenging problem, numerous researchers have incorporated prior knowledge into the acquisition of shapes. We will present the first approach to acquire shapes given a certain shape knowledge that computes always the global minimum of the involved functional which incorporates a Mumford-Shah like functional with a certain class of shape priors including statistic shape prior and dynamical shape prior. In order to analyze shapes, it is not only important to acquire shapes, but also to classify shapes. In this work, we follow the concept of defining a distance function that measures the dissimilarity of two given shapes. There are two different ways of obtaining such a distance function that we address in this work. Firstly, we model the set of all shapes as a metric space induced by the shortest path on an orbifold. The shortest path will provide us with a shape morphing, i.e., a continuous transformation from one shape into another. Secondly, we address the problem of shape matching that finds corresponding points on two shapes with respect to a preselected feature. Our main contribution for the problem of shape morphing lies in the immense acceleration of the morphing computation. Instead of solving partial resp. ordinary differential equations, we are able to solve this problem via a gradient descent approach that subsequently shortens the length of a path on the given manifold. During our runtime test, we observed a run-time acceleration of up to a factor of 1000. Shape matching is a classical discrete problem. If each shape is discretized by N shape points, most Computer Vision methods needed a cubic run-time. We will provide two approaches how to reduce this worst-case complexity to O(N2 log(N)). One approach exploits the planarity of the involved graph in order to efficiently compute N shortest path in a graph of O(N2) vertices. The other approach computes a minimal cut in a planar graph in O(N log(N)). In order to make this approach applicable to shape matching, we improved the run-time of a recently developed graph cut approach by an empirical factor of 2–4

Ventricular dilatation in aging and dementia

The general objective of this thesis was to study the causes and consequences of ventricular dilatation in aging and dementia. For this purpose, we used ventricular shape analysis to study potential new MRI markers of cognitive decline in aging, subjective memory complaints, mild cognitive impairment and Alzheimer's Disease. In addition, we designed a volumetric measure that may objectively quantify the disproportionate ventricular dilatation that is characteristic of Normal Pressure Hydrocephalus (NPH). We investigated the value of this measure for the selection of candidates with NPH for ventricular shunting, studied its association with NPH-like symptoms in the general population and used the measure to explore a possible cardiovascular origin of cerebral ventricular dilatation.UBL - phd migration 201

Learning Object Correspondences with the Observed Transport Shape Measure

We propose a learning method which introduces explicit knowledge to the object correspondence problem. Our approach uses an a priori learning set to compute a dense correspondence field between two objects, where the characteristics of the field bear close resemblance to those in the learning set. We introduce a new local shape measure we call the "observed transport measure", whose properties make it particularly amenable to the matching problem. From the values of our measure obtained at every point of the objects to be matched, we compute a distance matrix which embeds the correspondence problem in a highly expressive and redundant construct and facilitates its manipulation. We present two learning strategies that rely on the distance matrix and discuss their applications to the matching of a variety of 1-D, 2-D and 3-D objects, including the corpus callosum and ventricular surfaces

Proceedings of the Third International Workshop on Mathematical Foundations of Computational Anatomy - Geometrical and Statistical Methods for Modelling Biological Shape Variability

International audienceComputational anatomy is an emerging discipline at the interface of geometry, statistics and image analysis which aims at modeling and analyzing the biological shape of tissues and organs. The goal is to estimate representative organ anatomies across diseases, populations, species or ages, to model the organ development across time (growth or aging), to establish their variability, and to correlate this variability information with other functional, genetic or structural information. The Mathematical Foundations of Computational Anatomy (MFCA) workshop aims at fostering the interactions between the mathematical community around shapes and the MICCAI community in view of computational anatomy applications. It targets more particularly researchers investigating the combination of statistical and geometrical aspects in the modeling of the variability of biological shapes. The workshop is a forum for the exchange of the theoretical ideas and aims at being a source of inspiration for new methodological developments in computational anatomy. A special emphasis is put on theoretical developments, applications and results being welcomed as illustrations. Following the successful rst edition of this workshop in 20061 and second edition in New-York in 20082, the third edition was held in Toronto on September 22 20113. Contributions were solicited in Riemannian and group theoretical methods, geometric measurements of the anatomy, advanced statistics on deformations and shapes, metrics for computational anatomy, statistics of surfaces, modeling of growth and longitudinal shape changes. 22 submissions were reviewed by three members of the program committee. To guaranty a high level program, 11 papers only were selected for oral presentation in 4 sessions. Two of these sessions regroups classical themes of the workshop: statistics on manifolds and diff eomorphisms for surface or longitudinal registration. One session gathers papers exploring new mathematical structures beyond Riemannian geometry while the last oral session deals with the emerging theme of statistics on graphs and trees. Finally, a poster session of 5 papers addresses more application oriented works on computational anatomy