14,717 research outputs found
EmbraceNet for Activity: A Deep Multimodal Fusion Architecture for Activity Recognition
Human activity recognition using multiple sensors is a challenging but
promising task in recent decades. In this paper, we propose a deep multimodal
fusion model for activity recognition based on the recently proposed feature
fusion architecture named EmbraceNet. Our model processes each sensor data
independently, combines the features with the EmbraceNet architecture, and
post-processes the fused feature to predict the activity. In addition, we
propose additional processes to boost the performance of our model. We submit
the results obtained from our proposed model to the SHL recognition challenge
with the team name "Yonsei-MCML."Comment: Accepted in HASCA at ACM UbiComp/ISWC 2019, won the 2nd place in the
SHL Recognition Challenge 201
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Human 3D cellular model of hypoxic brain injury of prematurity.
Owing to recent medical and technological advances in neonatal care, infants born extremely premature have increased survival rates1,2. After birth, these infants are at high risk of hypoxic episodes because of lung immaturity, hypotension and lack of cerebral-flow regulation, and can develop a severe condition called encephalopathy of prematurity3. Over 80% of infants born before post-conception week 25 have moderate-to-severe long-term neurodevelopmental impairments4. The susceptible cell types in the cerebral cortex and the molecular mechanisms underlying associated gray-matter defects in premature infants remain unknown. Here we used human three-dimensional brain-region-specific organoids to study the effect of oxygen deprivation on corticogenesis. We identified specific defects in intermediate progenitors, a cortical cell type associated with the expansion of the human cerebral cortex, and showed that these are related to the unfolded protein response and changes. Moreover, we verified these findings in human primary cortical tissue and demonstrated that a small-molecule modulator of the unfolded protein response pathway can prevent the reduction in intermediate progenitors following hypoxia. We anticipate that this human cellular platform will be valuable for studying the environmental and genetic factors underlying injury in the developing human brain
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Predicting subsequent contralateral slipped capital femoral epiphysis: an evidence-based approach.
PurposeThe purpose of this study was to identify risk factors for developing a subsequent contralateral slipped capital femoral epiphysis (SCFE) and provide a prediction score to quantify risk of subsequent slip at the time of initial presentation.MethodsThis retrospective study included patients that presented with a unilateral SCFE between 2006 and 2017. Chart and radiographic review were performed to collect demographic, clinical and radiographic risk factors. Descriptive statistics, univariate analyses and multivariate regression analysis were used to compare risk factors between patients that did or did not develop a subsequent contralateral SCFE.ResultsThis study included 183 patients and 33 patients (18%) developed a subsequent contralateral SCFE. Younger age at time of initial presentation, lower modified Oxford Score and smaller difference in epiphyseal-diaphyseal angle between both sides during index presentation were significant predictors of subsequent contralateral SCFE. Specifically, age ≤ 11 years, modified Oxford Score ≤ 20 and difference in epiphyseal-diaphyseal angle of ≤ 21° between both hips were predictive of a contralateral slip (Area Under the Curve = 0.78; p < 0.05). The presence of each risk factor increased the risk of subsequent contralateral SCFE and having all three risk factors increased the risk to 73%.ConclusionThere is a significant risk of subsequent contralateral SCFE in patients with unilateral SCFE, and predictive risk factors include younger age, lower modified Oxford Score and smaller difference in epiphyseal-diaphyseal angle between the affected and unaffected hips.Level of evidenceLevel III
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PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers.
Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for PRP and BMAC in order to increase regenerative processes. The most common biomaterials utilized in conjunction with PRP and BMAC clinical trials are organic scaffolds and natural or synthetic polymers. This review will cover the combinatorial strategies of biomaterial carriers with PRP and BMAC for musculoskeletal conditions (MsCs) repair and regeneration in clinical trials. The main objective is to review the therapeutic use of PRP and BMAC as a treatment option for muscle, bone and cartilage injuries
Study of the Influence of Meals of Wheat and Oat Germs and Wild Rose Fruits on the Fermenting Microflora Activity of Rye-wheat Dough
The aim of the research was to study an influence of meals of wheat germs (WGM) and oat germs (OGM) in amount 10…20 %, and also ones of wild rose fruits (WRFM) in amount 2…6 % of the total mass of flour on the fermenting microflora of rye-wheat dough; and also to establish an influence of the experimental supplements on main microbiological processes in it.It has been established, that adding experimental meals favors the activation of bakery yeast. At introducing WGM, OGM and WRFM, its lifting force grows by 16.0–54.0, 6.0–18.0, 10.0–44.0 % respectively, and zymase and Maltase activity – by 16.0–53.3, 6.0–17.7 and 11.1–44.0 % and 18.8–55.0, 6.3 31.3 and 7.5–25.0 % respectively. It has been established, that there also takes place the activity increase of lactate bacteria in rye-wheat dough with adding meals of wheat, oat germs and wild rose fruits. It is possible at the expanse of adding an additional nutritive medium with the supplements.Such action of enriching raw materials on the microflora favors intensification of alcoholic and lactate fermentation that is established by data of acid accumulation and gas formation in rye-wheat dough. The counted indices at introducing WGM, OGM, WRFM increase by 39.0, 27.8, 33.9 % and 18.2, 13.6, 16.7 % respectively
An investigation into the impact of coaching strategies with respect to physical and performance characteristics of male youth of varying biological maturation
This thesis will be presented as two standalone experimental chapters which will culminate in a thesis discussion linking the two papers under the overarching concept of maturation in male youth. Chapter 2 is currently under review in ‘Cogent Medicine’, and the intention of Chapter 2 is to identify physical, injury and performance-based differences between maturational groups within a general school-based population of 8 youth. These observed differences within Chapter 2 will then inform the methodology and coaching strategies utilised within Chapter 3, which will investigate the effectiveness of various coaching methods in order to maximise adaptation, motor ability and injury prevention within each maturational group. The outcome of this thesis hopes to inform practitioners as to how they can best implement their training programmes to maximise learning and adaptation across a range of biological maturation levels. Rather than just knowing when training should occur which has been investigated previously, it is hoped this thesis will provide insight into how coaching should occur to maximise learning within this diverse adolescent population. Due to the layout of this thesis with the individual papers, there is an element of content repetition throughout Chapters 1,2,3 and 4 which needs to be acknowledged, although the various contexts provides uniqueness throughout
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Search for Magnetic Monopoles and Stable High-Electric-Charge Objects in 13 Tev Proton-Proton Collisions with the ATLAS Detector.
A search for magnetic monopoles and high-electric-charge objects is presented using 34.4 fb^{-1} of 13 TeV pp collision data collected by the ATLAS detector at the LHC during 2015 and 2016. The considered signature is based upon high ionization in the transition radiation tracker of the inner detector associated with a pencil-shape energy deposit in the electromagnetic calorimeter. The data were collected by a dedicated trigger based on the tracker high-threshold hit capability. The results are interpreted in models of Drell-Yan pair production of stable particles with two spin hypotheses (0 and 1/2) and masses ranging from 200 to 4000 GeV. The search improves by approximately a factor of 5 the constraints on the direct production of magnetic monopoles carrying one or two Dirac magnetic charges and stable objects with electric charge in the range 20≤|z|≤60 and extends the charge range to 60<|z|≤100
Prospects for discovering supersymmetric long-lived particles with MoEDAL
We present a study on the possibility of searching for long-lived
supersymmetric partners with the MoEDAL experiment at the LHC. MoEDAL is
sensitive to highly ionising objects such as magnetic monopoles or massive
(meta)stable electrically charged particles. We focus on prospects of directly
detecting long-lived sleptons in a phenomenologically realistic model which
involves an intermediate neutral long-lived particle in the decay chain. This
scenario is not yet excluded by the current data from ATLAS or CMS, and is
compatible with astrophysical constraints. Using Monte Carlo simulation, we
compare the sensitivities of MoEDAL versus ATLAS in scenarios where MoEDAL
could provide discovery reach complementary to ATLAS and CMS, thanks to looser
selection criteria combined with the virtual absence of background. It is also
interesting to point out that, in such scenarios, in which charged staus are
the main long-lived candidates, the relevant mass range for MoEDAL is
compatible with a potential role of Supersymmetry in providing an explanation
for the anomalous events observed by the ANITA detector.Comment: 12 pages, 6 figures; preliminary results presented in
arXiv:1903.11022; matches published version in EPJ
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