1,381 research outputs found
Liver Segmentation and its Application to Hepatic Interventions
The thesis addresses the development of an intuitive and accurate liver segmentation approach, its integration into software prototypes for the planning of liver interventions, and research on liver regeneration. The developed liver segmentation approach is based on a combination of the live wire paradigm and shape-based interpolation. Extended with two correction modes and integrated into a user-friendly workflow, the method has been applied to more than 5000 data sets. The combination of the liver segmentation with image analysis of hepatic vessels and tumors allows for the computation of anatomical and functional remnant liver volumes. In several projects with clinical partners world-wide, the benefit of the computer-assisted planning was shown. New insights about the postoperative liver function and regeneration could be gained, and most recent investigations into the analysis of MRI data provide the option to further improve hepatic intervention planning
Semiautomated 3D liver segmentation using computed tomography and magnetic resonance imaging
Le foie est un organe vital ayant une capacitĂ© de rĂ©gĂ©nĂ©ration exceptionnelle et un rĂŽle crucial dans le fonctionnement de lâorganisme. LâĂ©valuation du volume du foie est un outil important pouvant ĂȘtre utilisĂ© comme marqueur biologique de sĂ©vĂ©ritĂ© de maladies hĂ©patiques. La volumĂ©trie du foie est indiquĂ©e avant les hĂ©patectomies majeures, lâembolisation de la veine porte et la transplantation.
La méthode la plus répandue sur la base d'examens de tomodensitométrie (TDM) et d'imagerie par résonance magnétique (IRM) consiste à délimiter le contour du foie sur plusieurs coupes consécutives, un processus appelé la «segmentation».
Nous prĂ©sentons la conception et la stratĂ©gie de validation pour une mĂ©thode de segmentation semi-automatisĂ©e dĂ©veloppĂ©e Ă notre institution. Notre mĂ©thode reprĂ©sente une approche basĂ©e sur un modĂšle utilisant lâinterpolation variationnelle de forme ainsi que lâoptimisation de maillages de Laplace. La mĂ©thode a Ă©tĂ© conçue afin dâĂȘtre compatible avec la TDM ainsi que l' IRM.
Nous avons Ă©valuĂ© la rĂ©pĂ©tabilitĂ©, la fiabilitĂ© ainsi que lâefficacitĂ© de notre mĂ©thode semi-automatisĂ©e de segmentation avec deux Ă©tudes transversales conçues rĂ©trospectivement. Les rĂ©sultats de nos Ă©tudes de validation suggĂšrent que la mĂ©thode de segmentation confĂšre une fiabilitĂ© et rĂ©pĂ©tabilitĂ© comparables Ă la segmentation manuelle. De plus, cette mĂ©thode diminue de façon significative le temps dâinteraction, la rendant ainsi adaptĂ©e Ă la pratique clinique courante.
Dâautres Ă©tudes pourraient incorporer la volumĂ©trie afin de dĂ©terminer des marqueurs biologiques de maladie hĂ©patique basĂ©s sur le volume tels que la prĂ©sence de stĂ©atose, de fer, ou encore la mesure de fibrose par unitĂ© de volume.The liver is a vital abdominal organ known for its remarkable regenerative
capacity and fundamental role in organism viability. Assessment of liver volume is
an important tool which physicians use as a biomarker of disease severity. Liver
volumetry is clinically indicated prior to major hepatectomy, portal vein
embolization and transplantation.
The most popular method to determine liver volume from computed
tomography (CT) and magnetic resonance imaging (MRI) examinations involves
contouring the liver on consecutive imaging slices, a process called
âsegmentationâ. Segmentation can be performed either manually or in an
automated fashion.
We present the design concept and validation strategy for an innovative
semiautomated liver segmentation method developed at our institution. Our
method represents a model-based approach using variational shape interpolation
and Laplacian mesh optimization techniques. It is independent of training data,
requires limited user interactions and is robust to a variety of pathological cases.
Further, it was designed for compatibility with both CT and MRI examinations.
We evaluated the repeatability, agreement and efficiency of our
semiautomated method in two retrospective cross-sectional studies. The results of
our validation studies suggest that semiautomated liver segmentation can provide
strong agreement and repeatability when compared to manual segmentation.
Further, segmentation automation significantly shortens interaction time, thus
making it suitable for daily clinical practice.
Future studies may incorporate liver volumetry to determine volume-averaged
biomarkers of liver disease, such as such as fat, iron or fibrosis measurements per
unit volume. Segmental volumetry could also be assessed based on
subsegmentation of vascular anatomy
Accurate geometry reconstruction of vascular structures using implicit splines
3-D visualization of blood vessel from standard medical datasets (e.g. CT or MRI) play an important role in many clinical situations, including the diagnosis of vessel stenosis, virtual angioscopy, vascular surgery planning and computer aided vascular surgery. However, unlike other human organs, the vasculature system is a very complex network of vessel, which makes it a very challenging task to perform its 3-D visualization. Conventional techniques of medical volume data visualization are in general not well-suited for the above-mentioned tasks. This problem can be solved by reconstructing vascular geometry. Although various methods have been proposed for reconstructing vascular structures, most of these approaches are model-based, and are usually too ideal to correctly represent the actual variation presented by the cross-sections of a vascular structure. In addition, the underlying shape is usually expressed as polygonal meshes or in parametric forms, which is very inconvenient for implementing ramification of branching. As a result, the reconstructed geometries are not suitable for computer aided diagnosis and computer guided minimally invasive vascular surgery. In this research, we develop a set of techniques associated with the geometry reconstruction of vasculatures, including segmentation, modelling, reconstruction, exploration and rendering of vascular structures. The reconstructed geometry can not only help to greatly enhance the visual quality of 3-D vascular structures, but also provide an actual geometric representation of vasculatures, which can provide various benefits. The key findings of this research are as follows: 1. A localized hybrid level-set method of segmentation has been developed to extract the vascular structures from 3-D medical datasets. 2. A skeleton-based implicit modelling technique has been proposed and applied to the reconstruction of vasculatures, which can achieve an accurate geometric reconstruction of the vascular structures as implicit surfaces in an analytical form. 3. An accelerating technique using modern GPU (Graphics Processing Unit) is devised and applied to rendering the implicitly represented vasculatures. 4. The implicitly modelled vasculature is investigated for the application of virtual angioscopy
An Automated Liver Vasculature Segmentation from CT Scans for Hepatic Surgical Planning
Liver vasculature segmentation is a crucial step for liver surgical planning. Segmentation of liver vasculature is an important part of the 3D visualisation of the liver anatomy. The spatial relationship between vessels and other liver structures, like tumors and liver anatomic segments, helps in reducing the surgical treatment risks. However, liver vessels segmentation is a challenging task, that is due to low contrast with neighboring parenchyma, the complex anatomy, the very thin branches and very small vessels. This paper introduces a fully automated framework consist of four steps to segment the vessels inside the liver organ. Firstly, in the preprocessing step, a combination of two filtering techniques are used to extract and enhance vessels inside the liver region, first the vesselness filter is used to extract the vessels structure, and then the anisotropic coherence enhancing diffusion (CED) filter is used to enhance the intensity within the tubular vessels structure. This step is followed by a smart multiple thresholding to extract the initial vasculature segmentation. The liver vasculature structures, including hepatic veins connected to the inferior vena cava and the portal veins, are extracted. Finally, the inferior vena cava is segmented and excluded from the vessels segmentation, as it is not considered as part of the liver vasculature structure. The liver vessel segmentation method is validated on the publically available 3DIRCAD datasets. Dice coefficient (DSC) is used to evaluate the method, the average DSC score achieved a score 68.5%. The proposed approach succeeded to segment liver vasculature from the liver envelope accurately, which makes it as potential tool for clinical preoperative planning
Model-Based Visualization for Intervention Planning
Computer support for intervention planning is often a two-stage process: In a first stage, the relevant segmentation target structures are identified and delineated. In a second stage, image analysis results are employed for the actual planning process. In the first stage, model-based segmentation techniques are often used to reduce the interaction effort and increase the reproducibility. There is a similar argument to employ model-based techniques for the visualization as well. With increasingly more visualization options, users have many parameters to adjust in order to generate expressive visualizations. Surface models may be smoothed with a variety of techniques and parameters. Surface visualization and illustrative rendering techniques are controlled by a large set of additional parameters. Although interactive 3d visualizations should be flexible and support individual planning tasks, appropriate selection of visualization techniques and presets for their parameters is needed. In this chapter, we discuss this kind of visualization support. We refer to model-based visualization to denote the selection and parameterization of visualization techniques based on \u27a priori knowledge concerning visual perception, shapes of anatomical objects and intervention planning tasks
Use of the Resection Map system as guidance during hepatectomy
Industrial DesignIndustrial Design Engineerin
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