Occlusion and Slice-Based Volume Rendering Augmentation for PET-CT

Dual-modality positron emission tomography and computed tomography (PET-CT) depicts pathophysiological function with PET in an anatomical context provided by CT. Three-dimensional volume rendering approaches enable visualization of a two-dimensional slice of interest (SOI) from PET combined with direct volume rendering (DVR) from CT. However, because DVR depicts the whole volume, it may occlude a region of interest, such as a tumor in the SOI. Volume clipping can eliminate this occlusion by cutting away parts of the volume, but it requires intensive user involvement in deciding on the appropriate depth to clip. Transfer functions that are currently available can make the regions of interest visible, but this often requires complex parameter tuning and coupled pre-processing of the data to define the regions. Hence, we propose a new visualization algorithm where a SOI from PET is augmented by volumetric contextual information from a DVR of the counterpart CT so that the obtrusiveness from the CT in the SOI is minimized. Our approach automatically calculates an augmentation depth parameter by considering the occlusion information derived from the voxels of the CT in front of the PET SOI. The depth parameter is then used to generate an opacity weight function that controls the amount of contextual information visible from the DVR. We outline the improvements with our visualization approach compared to other slice-based and our previous approaches. We present the preliminary clinical evaluation of our visualization in a series of PET-CT studies from patients with non-small cell lung cancer

Feature-driven Volume Visualization of Medical Imaging Data

Direct volume rendering (DVR) is a volume visualization technique that has been proved to be a very powerful tool in many scientific visualization domains. Diagnostic medical imaging is one such domain in which DVR provides new capabilities for the analysis of complex cases and improves the efficiency of image interpretation workflows. However, the full potential of DVR in the medical domain has not yet been realized. A major obstacle for a better integration of DVR in the medical domain is the time-consuming process to optimize the rendering parameters that are needed to generate diagnostically relevant visualizations in which the important features that are hidden in image volumes are clearly displayed, such as shape and spatial localization of tumors, its relationship with adjacent structures, and temporal changes in the tumors. In current workflows, clinicians must manually specify the transfer function (TF), view-point (camera), clipping planes, and other visual parameters. Another obstacle for the adoption of DVR to the medical domain is the ever increasing volume of imaging data. The advancement of imaging acquisition techniques has led to a rapid expansion in the size of the data, in the forms of higher resolutions, temporal imaging acquisition to track treatment responses over time, and an increase in the number of imaging modalities that are used for a single procedure. The manual specification of the rendering parameters under these circumstances is very challenging. This thesis proposes a set of innovative methods that visualize important features in multi-dimensional and multi-modality medical images by automatically or semi-automatically optimizing the rendering parameters. Our methods enable visualizations necessary for the diagnostic procedure in which 2D slice of interest (SOI) can be augmented with 3D anatomical contextual information to provide accurate spatial localization of 2D features in the SOI; the rendering parameters are automatically computed to guarantee the visibility of 3D features; and changes in 3D features can be tracked in temporal data under the constraint of consistent contextual information. We also present a method for the efficient computation of visibility histograms (VHs) using adaptive binning, which allows our optimal DVR to be automated and visualized in real-time. We evaluated our methods by producing visualizations for a variety of clinically relevant scenarios and imaging data sets. We also examined the computational performance of our methods for these scenarios

Feature-driven Volume Visualization of Medical Imaging Data

Direct volume rendering (DVR) is a volume visualization technique that has been proved to be a very powerful tool in many scientific visualization domains. Diagnostic medical imaging is one such domain in which DVR provides new capabilities for the analysis of complex cases and improves the efficiency of image interpretation workflows. However, the full potential of DVR in the medical domain has not yet been realized. A major obstacle for a better integration of DVR in the medical domain is the time-consuming process to optimize the rendering parameters that are needed to generate diagnostically relevant visualizations in which the important features that are hidden in image volumes are clearly displayed, such as shape and spatial localization of tumors, its relationship with adjacent structures, and temporal changes in the tumors. In current workflows, clinicians must manually specify the transfer function (TF), view-point (camera), clipping planes, and other visual parameters. Another obstacle for the adoption of DVR to the medical domain is the ever increasing volume of imaging data. The advancement of imaging acquisition techniques has led to a rapid expansion in the size of the data, in the forms of higher resolutions, temporal imaging acquisition to track treatment responses over time, and an increase in the number of imaging modalities that are used for a single procedure. The manual specification of the rendering parameters under these circumstances is very challenging. This thesis proposes a set of innovative methods that visualize important features in multi-dimensional and multi-modality medical images by automatically or semi-automatically optimizing the rendering parameters. Our methods enable visualizations necessary for the diagnostic procedure in which 2D slice of interest (SOI) can be augmented with 3D anatomical contextual information to provide accurate spatial localization of 2D features in the SOI; the rendering parameters are automatically computed to guarantee the visibility of 3D features; and changes in 3D features can be tracked in temporal data under the constraint of consistent contextual information. We also present a method for the efficient computation of visibility histograms (VHs) using adaptive binning, which allows our optimal DVR to be automated and visualized in real-time. We evaluated our methods by producing visualizations for a variety of clinically relevant scenarios and imaging data sets. We also examined the computational performance of our methods for these scenarios

Stereoscopic bimanual interaction for 3D visualization

Virtual Environments (VE) are being widely used in various research fields for several decades such as 3D visualization, education, training and games. VEs have the potential to enhance the visualization and act as a general medium for human-computer interaction (HCI). However, limited research has evaluated virtual reality (VR) display technologies, monocular and binocular depth cues, for human depth perception of volumetric (non-polygonal) datasets. In addition, a lack of standardization of three-dimensional (3D) user interfaces (UI) makes it challenging to interact with many VE systems. To address these issues, this dissertation focuses on evaluation of effects of stereoscopic and head-coupled displays on depth judgment of volumetric dataset. It also focuses on evaluation of a two-handed view manipulation techniques which support simultaneous 7 degree-of-freedom (DOF) navigation (x,y,z + yaw,pitch,roll + scale) in a multi-scale virtual environment (MSVE). Furthermore, this dissertation evaluates auto-adjustment of stereo view parameters techniques for stereoscopic fusion problems in a MSVE. Next, this dissertation presents a bimanual, hybrid user interface which combines traditional tracking devices with computer-vision based "natural" 3D inputs for multi-dimensional visualization in a semi-immersive desktop VR system. In conclusion, this dissertation provides a guideline for research design for evaluating UI and interaction techniques

Spatial-Temporal Data Mining for Ocean Science: Data, Methodologies, and Opportunities

With the increasing amount of spatial-temporal~(ST) ocean data, numerous spatial-temporal data mining (STDM) studies have been conducted to address various oceanic issues, e.g., climate forecasting and disaster warning. Compared with typical ST data (e.g., traffic data), ST ocean data is more complicated with some unique characteristics, e.g., diverse regionality and high sparsity. These characteristics make it difficult to design and train STDM models. Unfortunately, an overview of these studies is still missing, hindering computer scientists to identify the research issues in ocean while discouraging researchers in ocean science from applying advanced STDM techniques. To remedy this situation, we provide a comprehensive survey to summarize existing STDM studies in ocean. Concretely, we first summarize the widely-used ST ocean datasets and identify their unique characteristics. Then, typical ST ocean data quality enhancement techniques are discussed. Next, we classify existing STDM studies for ocean into four types of tasks, i.e., prediction, event detection, pattern mining, and anomaly detection, and elaborate the techniques for these tasks. Finally, promising research opportunities are highlighted. This survey will help scientists from the fields of both computer science and ocean science have a better understanding of the fundamental concepts, key techniques, and open challenges of STDM in ocean

Towards Intelligent Telerobotics: Visualization and Control of Remote Robot

Human-machine cooperative or co-robotics has been recognized as the next generation of robotics. In contrast to current systems that use limited-reasoning strategies or address problems in narrow contexts, new co-robot systems will be characterized by their flexibility, resourcefulness, varied modeling or reasoning approaches, and use of real-world data in real time, demonstrating a level of intelligence and adaptability seen in humans and animals. The research I focused is in the two sub-field of co-robotics: teleoperation and telepresence. We firstly explore the ways of teleoperation using mixed reality techniques. I proposed a new type of display: hybrid-reality display (HRD) system, which utilizes commodity projection device to project captured video frame onto 3D replica of the actual target surface. It provides a direct alignment between the frame of reference for the human subject and that of the displayed image. The advantage of this approach lies in the fact that no wearing device needed for the users, providing minimal intrusiveness and accommodating users eyes during focusing. The field-of-view is also significantly increased. From a user-centered design standpoint, the HRD is motivated by teleoperation accidents, incidents, and user research in military reconnaissance etc. Teleoperation in these environments is compromised by the Keyhole Effect, which results from the limited field of view of reference. The technique contribution of the proposed HRD system is the multi-system calibration which mainly involves motion sensor, projector, cameras and robotic arm. Due to the purpose of the system, the accuracy of calibration should also be restricted within millimeter level. The followed up research of HRD is focused on high accuracy 3D reconstruction of the replica via commodity devices for better alignment of video frame. Conventional 3D scanner lacks either depth resolution or be very expensive. We proposed a structured light scanning based 3D sensing system with accuracy within 1 millimeter while robust to global illumination and surface reflection. Extensive user study prove the performance of our proposed algorithm. In order to compensate the unsynchronization between the local station and remote station due to latency introduced during data sensing and communication, 1-step-ahead predictive control algorithm is presented. The latency between human control and robot movement can be formulated as a linear equation group with a smooth coefficient ranging from 0 to 1. This predictive control algorithm can be further formulated by optimizing a cost function. We then explore the aspect of telepresence. Many hardware designs have been developed to allow a camera to be placed optically directly behind the screen. The purpose of such setups is to enable two-way video teleconferencing that maintains eye-contact. However, the image from the see-through camera usually exhibits a number of imaging artifacts such as low signal to noise ratio, incorrect color balance, and lost of details. Thus we develop a novel image enhancement framework that utilizes an auxiliary color+depth camera that is mounted on the side of the screen. By fusing the information from both cameras, we are able to significantly improve the quality of the see-through image. Experimental results have demonstrated that our fusion method compares favorably against traditional image enhancement/warping methods that uses only a single image

AvatarCraft: Transforming Text into Neural Human Avatars with Parameterized Shape and Pose Control

Neural implicit fields are powerful for representing 3D scenes and generating high-quality novel views, but it remains challenging to use such implicit representations for creating a 3D human avatar with a specific identity and artistic style that can be easily animated. Our proposed method, AvatarCraft, addresses this challenge by using diffusion models to guide the learning of geometry and texture for a neural avatar based on a single text prompt. We carefully design the optimization framework of neural implicit fields, including a coarse-to-fine multi-bounding box training strategy, shape regularization, and diffusion-based constraints, to produce high-quality geometry and texture. Additionally, we make the human avatar animatable by deforming the neural implicit field with an explicit warping field that maps the target human mesh to a template human mesh, both represented using parametric human models. This simplifies animation and reshaping of the generated avatar by controlling pose and shape parameters. Extensive experiments on various text descriptions show that AvatarCraft is effective and robust in creating human avatars and rendering novel views, poses, and shapes. Our project page is: https://avatar-craft.github.io/.Comment: ICCV 2023 Camera Read

Visibility-driven PET-CT Visualisation with Region of Interest (ROI) Segmentation

Multi-modality positron emission tomography – computed tomography (PET-CT) visualises biological and physiological functions (from PET) as region of interests (ROIs) within a higher resolution anatomical reference frame (from CT). The need to efficiently assess and assimilate the information from these co-aligned volumes simultaneously has stimulated new visualisation techniques that combine 3D volume rendering with interactive transfer functions to enable efficient manipulation of these volumes. However, in typical multi-modality volume rendering visualisation, the transfer functions for the volumes are manipulated in isolation with the resulting volumes being fused, thus failing to exploit the spatial correlation that exists between the aligned volumes. Such lack of feedback makes multi-modality transfer function manipulation to be complex and time-consuming. Further, transfer function alone is often insufficient to select the ROIs when it comprises of similar voxel properties to those of non-relevant regions. In this study, we propose a new ROI-based multi-modality visibility-driven transfer function (m2-vtf) for PET-CT visualisation. We present a novel ‘visibility’ metrics, a fundamental optical property that represents how much of the ROIs are visible to the users, and use it to measure the visibility of the ROIs in PET in relation to how it is affected by transfer function manipulations to its counterpart CT. To overcome the difficulty in ROI selection, we provide an intuitive ROIs selection tool based on automated PET segmentation. We further present a multi-modality transfer function automation where the visibility metrics from the PET ROIs are used to automate its CT’s transfer function. Our GPU implementation achieved an interactive visualisation of multi-modality PET-CT with efficient and intuitive transfer function manipulations