Multi-objective particle swarm optimization for the structural design of concentric tube continuum robots for medical applications

Concentric tube robots belong to the class of continuum robotic systems whose morphology is described by continuous tangent curvature vectors. They are composed of multiple, interacting tubes nested inside one another and are characterized by their inherent flexibility. Concentric tube continuum robots equipped with tools at their distal end have high potential in minimally invasive surgery. Their morphology enables them to reach sites within the body that are inaccessible with commercial tools or that require large incisions. Further, they can be deployed through a tight lumen or follow a nonlinear path. Fundamental research has been the focus during the last years bringing them closer to the operating room. However, there remain challenges that require attention. The structural synthesis of concentric tube continuum robots is one of these challenges, as these types of robots are characterized by their large parameter space. On the one hand, this is advantageous, as they can be deployed in different patients, anatomies, or medical applications. On the other hand, the composition of the tubes and their design is not a straightforward task but one that requires intensive knowledge of anatomy and structural behavior. Prior to the utilization of such robots, the composition of tubes (i.e. the selection of design parameters and application-specific constraints) must be solved to determine a robotic design that is specifically targeted towards an application or patient. Kinematic models that describe the change in morphology and complex motion increase the complexity of this synthesis, as their mathematical description is highly nonlinear. Thus, the state of the art is concerned with the structural design of these types of robots and proposes optimization algorithms to solve for a composition of tubes for a specific patient case or application. However, existing approaches do not consider the overall parameter space, cannot handle the nonlinearity of the model, or multiple objectives that describe most medical applications and tasks. This work aims to solve these fundamental challenges by solving the parameter optimization problem by utilizing a multi-objective optimization algorithm. The main concern of this thesis is the general methodology to solve for patient- and application-specific design of concentric tube continuum robots and presents key parameters, objectives, and constraints. The proposed optimization method is based on evolutionary concepts that can handle multiple objectives, where the set of parameters is represented by a decision vector that can be of variable dimension in multidimensional space. Global optimization algorithms specifically target the constrained search space of concentric tube continuum robots and nonlinear optimization enables to handle the highly nonlinear elasticity modeling. The proposed methodology is then evaluated based on three examples that include cooperative task deployment of two robotic arms, structural stiffness optimization under the consideration of workspace constraints and external forces, and laser-induced thermal therapy in the brain using a concentric tube continuum robot. In summary, the main contributions are 1) the development of an optimization methodology that describes the key parameters, objectives, and constraints of the parameter optimization problem of concentric tube continuum robots, 2) the selection of an appropriate optimization algorithm that can handle the multidimensional search space and diversity of the optimization problem with multiple objectives, and 3) the evaluation of the proposed optimization methodology and structural synthesis based on three real applications

The design and applications of the african buffalo algorithm for general optimization problems

Optimization, basically, is the economics of science. It is concerned with the need to maximize profit and minimize cost in terms of time and resources needed to execute a given project in any field of human endeavor. There have been several scientific investigations in the past several decades on discovering effective and efficient algorithms to providing solutions to the optimization needs of mankind leading to the development of deterministic algorithms that provide exact solutions to optimization problems. In the past five decades, however, the attention of scientists has shifted from the deterministic algorithms to the stochastic ones since the latter have proven to be more robust and efficient, even though they do not guarantee exact solutions. Some of the successfully designed stochastic algorithms include Simulated Annealing, Genetic Algorithm, Ant Colony Optimization, Particle Swarm Optimization, Bee Colony Optimization, Artificial Bee Colony Optimization, Firefly Optimization etc. A critical look at these ‘efficient’ stochastic algorithms reveals the need for improvements in the areas of effectiveness, the number of several parameters used, premature convergence, ability to search diverse landscapes and complex implementation strategies. The African Buffalo Optimization (ABO), which is inspired by the herd management, communication and successful grazing cultures of the African buffalos, is designed to attempt solutions to the observed shortcomings of the existing stochastic optimization algorithms. Through several experimental procedures, the ABO was used to successfully solve benchmark optimization problems in mono-modal and multimodal, constrained and unconstrained, separable and non-separable search landscapes with competitive outcomes. Moreover, the ABO algorithm was applied to solve over 100 out of the 118 benchmark symmetric and all the asymmetric travelling salesman’s problems available in TSPLIB95. Based on the successful experimentation with the novel algorithm, it is safe to conclude that the ABO is a worthy contribution to the scientific literature

Combining Differential Kinematics and Optical Flow for Automatic Labeling of Continuum Robots in Minimally Invasive Surgery

International audienceThe segmentation of continuum robots in medical images can be of interest for analyzing surgical procedures or for controlling them. However, the automatic segmentation of continuous and flexible shapes is not an easy task. On one hand conventional approaches are not adapted to the specificities of these instruments, such as imprecise kinematic models, and on the other hand techniques based on deep-learning showed interesting capabilities but need many manually labeled images. In this article we propose a novel approach for segmenting continuum robots on endoscopic images, which requires no prior on the instrument visual appearance and no manual annotation of images. The method relies on the use of the combination of kinematic models and differential kinematic models of the robot and the analysis of optical flow in the images. A cost function aggregating information from the acquired image, from optical flow and from robot encoders is optimized using particle swarm optimization and provides estimated parameters of the pose of the continuum instrument and a mask defining the instrument in the image. In addition a temporal consistency is assessed in order to improve stochastic optimization and reject outliers. The proposed approach has been tested for the robotic instruments of a flexible endoscopy platform both for benchtop acquisitions and an in vivo video. The results show the ability of the technique to correctly segment the instruments without a prior, and in challenging conditions. The obtained segmentation can be used for several applications, for instance for providing automatic labels for machine learning techniques