Inconstancy of finite and infinite sequences

In order to study large variations or fluctuations of finite or infinite sequences (time series), we bring to light an 1868 paper of Crofton and the (Cauchy-)Crofton theorem. After surveying occurrences of this result in the literature, we introduce the inconstancy of a sequence and we show why it seems more pertinent than other criteria for measuring its variational complexity. We also compute the inconstancy of classical binary sequences including some automatic sequences and Sturmian sequences.Comment: Accepted by Theoretical Computer Scienc

Registration of histology and magnetic resonance imaging of the brain

Combining histology and non-invasive imaging has been attracting the attention of the medical imaging community for a long time, due to its potential to correlate macroscopic information with the underlying microscopic properties of tissues. Histology is an invasive procedure that disrupts the spatial arrangement of the tissue components but enables visualisation and characterisation at a cellular level. In contrast, macroscopic imaging allows non-invasive acquisition of volumetric information but does not provide any microscopic details. Through the establishment of spatial correspondences obtained via image registration, it is possible to compare micro- and macroscopic information and to recover the original histological arrangement in three dimensions. In this thesis, I present: (i) a survey of the literature relative to methods for histology reconstruction with and without the help of 3D medical imaging; (ii) a graph-theoretic method for histology volume reconstruction from sets of 2D sections, without external information; (iii) a method for multimodal 2D linear registration between histology and MRI based on partial matching of shape-informative boundaries