A Review of Locomotion Systems for Capsule Endoscopy

Wireless capsule endoscopy for gastrointestinal (GI) tract is a modern technology that has the potential to replace conventional endoscopy techniques. Capsule endoscopy is a pill-shaped device embedded with a camera, a coin battery, and a data transfer. Without a locomotion system, this capsule endoscopy can only passively travel inside the GI tract via natural peristalsis, thus causing several disadvantages such as inability to control and stop, and risk of capsule retention. Therefore, a locomotion system needs to be added to optimize the current capsule endoscopy. This review summarizes the state-of-the-art locomotion methods along with the desired locomotion features such as size, speed, power, and temperature and compares the properties of different methods. In addition, properties and motility mechanisms of the GI tract are described. The main purpose of this review is to understand the features of GI tract and diverse locomotion methods in order to create a future capsule endoscopy compatible with GI tract properties

Frontiers of robotic endoscopic capsules: a review

Digestive diseases are a major burden for society and healthcare systems, and with an aging population, the importance of their effective management will become critical. Healthcare systems worldwide already struggle to insure quality and affordability of healthcare delivery and this will be a significant challenge in the midterm future. Wireless capsule endoscopy (WCE), introduced in 2000 by Given Imaging Ltd., is an example of disruptive technology and represents an attractive alternative to traditional diagnostic techniques. WCE overcomes conventional endoscopy enabling inspection of the digestive system without discomfort or the need for sedation. Thus, it has the advantage of encouraging patients to undergo gastrointestinal (GI) tract examinations and of facilitating mass screening programmes. With the integration of further capabilities based on microrobotics, e.g. active locomotion and embedded therapeutic modules, WCE could become the key-technology for GI diagnosis and treatment. This review presents a research update on WCE and describes the state-of-the-art of current endoscopic devices with a focus on research-oriented robotic capsule endoscopes enabled by microsystem technologies. The article also presents a visionary perspective on WCE potential for screening, diagnostic and therapeutic endoscopic procedures

Mobility, Navigation and Localization Towards Robotic Endoscopy

With significant progress being made towards improving endoscope technology such as capsule endoscopy and robotic endoscopy, the development of advanced strategies for manipulating, controlling and more generally, easing the accessibility of these devices for physicians is an important next step. This work presents the development of several robotic platforms for experimentally testing navigation and localization strategies in robotic endoscopy followed by the development and testing of navigation strategies using these devices. Finally, visual and visual inertial localization and mapping is explored on two of these robotic systems. We first present a detailed description on the state-of-the-art with regard to minimally invasive robotic surgery and then follow this with in-depth description of our design and validation of two important systems, the Robotic Endoscope Platform (REP) and the Modular Endoscopy Simulation Apparatus (MESA), for exploring some of the challenges in robotic endoscopy. Following these descriptions we present a technique for autonomous navigation of the REP within the MESA as well as an attempt at applying Simultaneous Localization and Mapping (SLAM) to allow for the real-time localization of this system. Finally, we transition these techniques to the Endoculus, a complete robotic endoscope suitable for in vivo testing, and demonstrate both autonomous navigation for this device, and the implementation of three different SLAM systems for localization and mapping of the Endoculus system in real-time. Throughout these experiments we demonstrate the potential for advanced methods in computer vision along with other sensory techniques to substantially benefit endoscopy, enabling greater and greater autonomy of these systems and furthering the case for robotic endoscopy as a whole.</p

Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation

Early diagnosis of colorectal cancer substantially improves survival. However, over half of cases are diagnosed late due to the demand for colonoscopy—the ‘gold standard’ for screening—exceeding capacity. Colonoscopy is limited by the outdated design of conventional endoscopes, which are associated with high complexity of use, cost and pain. Magnetic endoscopes are a promising alternative and overcome the drawbacks of pain and cost, but they struggle to reach the translational stage as magnetic manipulation is complex and unintuitive. In this work, we use machine vision to develop intelligent and autonomous control of a magnetic endoscope, enabling non-expert users to effectively perform magnetic colonoscopy in vivo. We combine the use of robotics, computer vision and advanced control to offer an intuitive and effective endoscopic system. Moreover, we define the characteristics required to achieve autonomy in robotic endoscopy. The paradigm described here can be adopted in a variety of applications where navigation in unstructured environments is required, such as catheters, pancreatic endoscopy, bronchoscopy and gastroscopy. This work brings alternative endoscopic technologies closer to the translational stage, increasing the availability of early-stage cancer treatments

Doctor of Philosophy

dissertationThis dissertation presents results documenting advancements on the control of untethered magnetic devices, such as magnetic \microrobots" and magnetically actuated capsuleendoscopes, motivated by problems in minimally invasive medicine. This dissertationfocuses on applying rotating magnetic elds for magnetic manipulation. The contributions include advancements in the way that helical microswimmers (devices that mimicthe propulsion of bacterial agella) are controlled in the presence of gravitational forces, advancements in ways that groups of untethered magnetic devices can be dierentiated and semi-independently controlled, advancements in the way that untethered magnetic device can be controlled with a single rotating permanent magnet, and an improved understanding in the nature of the magnetic force applied to an untethered device by a rotating magnet

Robotic, self-propelled, self-steerable, and disposable colonoscopes: Reality or pipe dream? A state of the art review.

Robotic colonoscopes could potentially provide a comfortable, less painful and safer alternative to standard colonoscopy. Recent exciting developments in this field are pushing the boundaries to what is possible in the future. This article provides a comprehensive review of the current work in robotic colonoscopes including self-propelled, steerable and disposable endoscopes that could be alternatives to standard colonoscopy. We discuss the advantages and disadvantages of these systems currently in development and highlight the technical readiness of each system to help the reader understand where and when such systems may be available for routine clinical use and get an idea of where and in which situation they can best be deployed