100,926 research outputs found
Microsoft institute for high performance computing
An overview of the Microsoft Institute for High Performance Computing at the University of Southampto
High Energy Physics from High Performance Computing
We discuss Quantum Chromodynamics calculations using the lattice regulator.
The theory of the strong force is a cornerstone of the Standard Model of
particle physics. We present USQCD collaboration results obtained on Argonne
National Lab's Intrepid supercomputer that deepen our understanding of these
fundamental theories of Nature and provide critical support to frontier
particle physics experiments and phenomenology.Comment: Proceedings of invited plenary talk given at SciDAC 2009, San Diego,
June 14-18, 2009, on behalf of the USQCD collaboratio
High performance computing and communications program
A review of the High Performance Computing and Communications (HPCC) program is provided in vugraph format. The goals and objectives of this federal program are as follows: extend U.S. leadership in high performance computing and computer communications; disseminate the technologies to speed innovation and to serve national goals; and spur gains in industrial competitiveness by making high performance computing integral to design and production
A Pattern Language for High-Performance Computing Resilience
High-performance computing systems (HPC) provide powerful capabilities for
modeling, simulation, and data analytics for a broad class of computational
problems. They enable extreme performance of the order of quadrillion
floating-point arithmetic calculations per second by aggregating the power of
millions of compute, memory, networking and storage components. With the
rapidly growing scale and complexity of HPC systems for achieving even greater
performance, ensuring their reliable operation in the face of system
degradations and failures is a critical challenge. System fault events often
lead the scientific applications to produce incorrect results, or may even
cause their untimely termination. The sheer number of components in modern
extreme-scale HPC systems and the complex interactions and dependencies among
the hardware and software components, the applications, and the physical
environment makes the design of practical solutions that support fault
resilience a complex undertaking. To manage this complexity, we developed a
methodology for designing HPC resilience solutions using design patterns. We
codified the well-known techniques for handling faults, errors and failures
that have been devised, applied and improved upon over the past three decades
in the form of design patterns. In this paper, we present a pattern language to
enable a structured approach to the development of HPC resilience solutions.
The pattern language reveals the relations among the resilience patterns and
provides the means to explore alternative techniques for handling a specific
fault model that may have different efficiency and complexity characteristics.
Using the pattern language enables the design and implementation of
comprehensive resilience solutions as a set of interconnected resilience
patterns that can be instantiated across layers of the system stack.Comment: Proceedings of the 22nd European Conference on Pattern Languages of
Program
Empowering precision medicine through high performance computing clusters
The role of High Performance Computing (HPC) in Medicine is greatly increase in these last years,
moving from basic research to the clinics. With the advent of Next Generation Sequencing (NGS)
technologies, diverse areas of human health have been investigated through different omics
techniques. The extensive use of these NGS platforms to high throughput profile human health
issues in a cost-efficient manner, is generating huge amount of sequencing data pushing
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bioinformatic research in the big-data field. Speed, accuracy and reproducibility of massively
sequencing analysis have allowed to transfer molecular biology knowledge into precision medicine.
Furthermore, Molecular Dynamics (MD) earned a great importance in aiding genome research.
Sequencing studies of cancer have allowed to detect and characterize mutated genes that drive
tumorigenesis. As a complementary approach, from a biophysical perspective, MD simulations,
executed on HPC architectures, have permitted to investigate the role played by pathological
mutations on the molecular mechanism of activation
IRPF90: a programming environment for high performance computing
IRPF90 is a Fortran programming environment which helps the development of
large Fortran codes. In Fortran programs, the programmer has to focus on the
order of the instructions: before using a variable, the programmer has to be
sure that it has already been computed in all possible situations. For large
codes, it is common source of error. In IRPF90 most of the order of
instructions is handled by the pre-processor, and an automatic mechanism
guarantees that every entity is built before being used. This mechanism relies
on the {needs/needed by} relations between the entities, which are built
automatically. Codes written with IRPF90 execute often faster than Fortran
programs, are faster to write and easier to maintain.Comment: 18 pages, 14 figure
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