Mathematical modelling of angiogenesis and vascular adaptation

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Yielding dynamics of a Herschel-Bulkley fluid: a critical-like fluidization behaviour

The shear-induced fluidization of a carbopol microgel is investigated during long start-up experiments using combined rheology and velocimetry in Couette cells of varying gap widths and boundary conditions. As already described in [Divoux et al., {\it Phys. Rev. Lett.}, 2010, {\bf 104}, 208301], we show that the fluidization process of this simple yield stress fluid involves a transient shear-banding regime whose duration $\tau_f$ decreases as a power law of the applied shear rate \gp. Here we go one step further by an exhaustive investigation of the influence of the shearing geometry through the gap width $e$ and the boundary conditions. While slip conditions at the walls seem to have a negligible influence on the fluidization time $\tau_f$, different fluidization processes are observed depending on \gp and $e$: the shear band remains almost stationary for several hours at low shear rates or small gap widths before strong fluctuations lead to a homogeneous flow, whereas at larger values of \gp or $e$, the transient shear band is seen to invade the whole gap in a much smoother way. Still, the power-law behaviour appears as very robust and hints to critical-like dynamics. To further discuss these results, we propose (i) a qualitative scenario to explain the induction-like period that precedes full fluidization and (ii) an analogy with critical phenomena that naturally leads to the observed power laws if one assumes that the yield point is the critical point of an underlying out-of-equilibrium phase transition.Comment: 16 pages, 14+2 figures, published in Soft Matte

Mechano-electric heterogeneity of the myocardium as a paradigm of its function

Myocardial heterogeneity is well appreciated and widely documented, from sub-cellular to organ levels. This paper reviews significant achievements of the group, led by Professor Vladimir S. Markhasin, Russia, who was one of the pioneers in studying and interpreting the relevance of cardiac functional heterogeneity

A Robust Zero-Calibration RF-based Localization System for Realistic Environments

Due to the noisy indoor radio propagation channel, Radio Frequency (RF)-based location determination systems usually require a tedious calibration phase to construct an RF fingerprint of the area of interest. This fingerprint varies with the used mobile device, changes of the transmit power of smart access points (APs), and dynamic changes in the environment; requiring re-calibration of the area of interest; which reduces the technology ease of use. In this paper, we present IncVoronoi: a novel system that can provide zero-calibration accurate RF-based indoor localization that works in realistic environments. The basic idea is that the relative relation between the received signal strength from two APs at a certain location reflects the relative distance from this location to the respective APs. Building on this, IncVoronoi incrementally reduces the user ambiguity region based on refining the Voronoi tessellation of the area of interest. IncVoronoi also includes a number of modules to efficiently run in realtime as well as to handle practical deployment issues including the noisy wireless environment, obstacles in the environment, heterogeneous devices hardware, and smart APs. We have deployed IncVoronoi on different Android phones using the iBeacons technology in a university campus. Evaluation of IncVoronoi with a side-by-side comparison with traditional fingerprinting techniques shows that it can achieve a consistent median accuracy of 2.8m under different scenarios with a low beacon density of one beacon every 44m2. Compared to fingerprinting techniques, whose accuracy degrades by at least 156%, this accuracy comes with no training overhead and is robust to the different user devices, different transmit powers, and over temporal changes in the environment. This highlights the promise of IncVoronoi as a next generation indoor localization system.Comment: 9 pages, 13 figures, published in SECON 201

Economic Cooperation in ASEAN and the Rise of China

Over the past decade, the Association of Southeast Asian Nations (ASEAN) has shifted from its original focus on regional peace and stability toward embracing a progressively economics-dominated agenda. A multitude of initiatives concerning cooperation in the areas of trade and finance have been launched. At the 2003 ASEAN Summit in Bali, ASEAN leaders even declared the goal of establishing an ASEAN Economic Community by 2020. This paper discusses two factors that have contributed to ASEAN's increasing focus on economic cooperation: (1) the Asian financial crisis, and (2) the emergence of China as a major international and economic power. It is argued that these determinants have paved the way for closer economic cooperation within the region despite the great heterogeneity and conflicting interests of the ASEAN member countries

Metastability at the Yield-Stress Transition in Soft Glasses

We study the solid-to-liquid transition in a two-dimensional fully periodic soft-glassy model with an imposed spatially heterogeneous stress. The model we consider consists of droplets of a dispersed phase jammed together in a continuous phase. When the peak value of the stress gets close to the yield stress of the material, we find that the whole system intermittently tunnels to a metastable "fluidized" state, which relaxes back to a metastable "solid" state by means of an elastic-wave dissipation. This macroscopic scenario is studied through the microscopic displacement field of the droplets, whose time statistics displays a remarkable bimodality. Metastability is rooted in the existence, in a given stress range, of two distinct stable rheological branches as well as long-range correlations (e.g., large dynamic heterogeneity) developed in the system. Finally, we show that a similar behavior holds for a pressure-driven flow, thus suggesting possible experimental tests.Comment: 13 pages, 11 figure