Prospects and limitations of full-text index structures in genome analysis

The combination of incessant advances in sequencing technology producing large amounts of data and innovative bioinformatics approaches, designed to cope with this data flood, has led to new interesting results in the life sciences. Given the magnitude of sequence data to be processed, many bioinformatics tools rely on efficient solutions to a variety of complex string problems. These solutions include fast heuristic algorithms and advanced data structures, generally referred to as index structures. Although the importance of index structures is generally known to the bioinformatics community, the design and potency of these data structures, as well as their properties and limitations, are less understood. Moreover, the last decade has seen a boom in the number of variant index structures featuring complex and diverse memory-time trade-offs. This article brings a comprehensive state-of-the-art overview of the most popular index structures and their recently developed variants. Their features, interrelationships, the trade-offs they impose, but also their practical limitations, are explained and compared

Parallel data compression

Data compression schemes remove data redundancy in communicated and stored data and increase the effective capacities of communication and storage devices. Parallel algorithms and implementations for textual data compression are surveyed. Related concepts from parallel computation and information theory are briefly discussed. Static and dynamic methods for codeword construction and transmission on various models of parallel computation are described. Included are parallel methods which boost system speed by coding data concurrently, and approaches which employ multiple compression techniques to improve compression ratios. Theoretical and empirical comparisons are reported and areas for future research are suggested

Wavefront Longest Common Subsequence Algorithm On Multicore And Gpgpu Platform.

String comparison is a central operation in numerous applications. It has a critical task in many operations such as data mining, spelling error correction and molecular biology (Tan et al, 2007; Michailidis and Margaritis, 2000)

Lempel-Ziv Parsing in External Memory

For decades, computing the LZ factorization (or LZ77 parsing) of a string has been a requisite and computationally intensive step in many diverse applications, including text indexing and data compression. Many algorithms for LZ77 parsing have been discovered over the years; however, despite the increasing need to apply LZ77 to massive data sets, no algorithm to date scales to inputs that exceed the size of internal memory. In this paper we describe the first algorithm for computing the LZ77 parsing in external memory. Our algorithm is fast in practice and will allow the next generation of text indexes to be realised for massive strings and string collections.Comment: 10 page