Proceedings of Abstracts Engineering and Computer Science Research Conference 2019

© 2019 The Author(s). This is an open-access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For further details please see https://creativecommons.org/licenses/by/4.0/. Note: Keynote: Fluorescence visualisation to evaluate effectiveness of personal protective equipment for infection control is © 2019 Crown copyright and so is licensed under the Open Government Licence v3.0. Under this licence users are permitted to copy, publish, distribute and transmit the Information; adapt the Information; exploit the Information commercially and non-commercially for example, by combining it with other Information, or by including it in your own product or application. Where you do any of the above you must acknowledge the source of the Information in your product or application by including or linking to any attribution statement specified by the Information Provider(s) and, where possible, provide a link to this licence: http://www.nationalarchives.gov.uk/doc/open-government-licence/version/3/This book is the record of abstracts submitted and accepted for presentation at the Inaugural Engineering and Computer Science Research Conference held 17th April 2019 at the University of Hertfordshire, Hatfield, UK. This conference is a local event aiming at bringing together the research students, staff and eminent external guests to celebrate Engineering and Computer Science Research at the University of Hertfordshire. The ECS Research Conference aims to showcase the broad landscape of research taking place in the School of Engineering and Computer Science. The 2019 conference was articulated around three topical cross-disciplinary themes: Make and Preserve the Future; Connect the People and Cities; and Protect and Care

Legal Myths of Ebola Preparedness and Response

In March 2014, Ebola viral disease (“EVD”) emerged from several West African countries as a substantial threat to global health. Through a series of core legal powers pursuant to its declaration of a public health emergency of international concern (“PHEIC”) on August 8, 2014, the World Health Organization (“WHO”) averted a global health disaster by requiring member countries to engage in mul- tiple public health interventions. These efficacious WHO-mandated measures included implementation of border closures to limit the spread of EVD within and outside of countries like Guinea, Liberia, Senegal, and Sierra Leone. Industrialized nations, including the United States, responded swiftly as well through their own emergency declarations. Resulting emergency legal powers enabled strong coordination among federal, state, and local actors to systematically identify and limit cases. Among these powers, the federal Centers for Disease Control and Prevention (“CDC”) required state and local governments to follow its national guidance on quarantine and isolation procedures for persons exposed to or infected with EVD. This led to the justified quarantine of health care workers (“HCWs”) returning from treating Ebola patients in West African “hot zones.” In collaboration with CDC, U.S. Customs and Border Control agents screened thousands of incoming passengers at multiple domestic airports to find and contain numerous, potential cases of EVD. The Food and Drug Administra- tion (“FDA”) worked in real-time to authorize the use of an extensive array of experimental tests or drugs proven effective in identifying cases and treating EVD patients. These (and other) legally-supported efforts worked in unison to control the impacts, and protect the public’s health

Legal Myths of Ebola Preparedness and Response

In March 2014, Ebola viral disease (“EVD”) emerged from several West African countries as a substantial threat to global health. Through a series of core legal powers pursuant to its declaration of a public health emergency of international concern (“PHEIC”) on August 8, 2014, the World Health Organization (“WHO”) averted a global health disaster by requiring member countries to engage in mul- tiple public health interventions. These efficacious WHO-mandated measures included implementation of border closures to limit the spread of EVD within and outside of countries like Guinea, Liberia, Senegal, and Sierra Leone. Industrialized nations, including the United States, responded swiftly as well through their own emergency declarations. Resulting emergency legal powers enabled strong coordination among federal, state, and local actors to systematically identify and limit cases. Among these powers, the federal Centers for Disease Control and Prevention (“CDC”) required state and local governments to follow its national guidance on quarantine and isolation procedures for persons exposed to or infected with EVD. This led to the justified quarantine of health care workers (“HCWs”) returning from treating Ebola patients in West African “hot zones.” In collaboration with CDC, U.S. Customs and Border Control agents screened thousands of incoming passengers at multiple domestic airports to find and contain numerous, potential cases of EVD. The Food and Drug Administra- tion (“FDA”) worked in real-time to authorize the use of an extensive array of experimental tests or drugs proven effective in identifying cases and treating EVD patients. These (and other) legally-supported efforts worked in unison to control the impacts, and protect the public’s health

Whose Heritage?

This edited collection challenges and re-imagines what is ‘heritage’ in Britain as a globalised, vernacular, cosmopolitan ‘post-nation’. It takes its inspiration from the foundational work of public intellectual Stuart Hall (1932-2014). Hall was instrumental in calling out embedded elitist conceptions of ‘The Heritage’ of Britain. The book’s authors challenge us to reconsider what is valued about Britain’s past, its culture and its citizens. Populist discourses around the world, including Brexit and ‘culture war’ declarations in the UK, demonstrate how heritage and ideas of the past are mobilised in racist politics. The multidisciplinary chapters of this book offer critical inspections of these politics, and dig deeply into the problems of theory, policy and practice in today’s academia, society and heritage sector. The volume challenges the lack of action since Hall rebuked ‘The Heritage’ twenty years ago. The authors featured here are predominantly Black Britons, academics and practitioners engaged in culture and heritage, spurred by the killing of George Floyd and the rise of the Black Lives Matter movement to contest racist practices and structures that support them. The primary audience will be academics, but it will also attract culture sector practitioners and heritage institutions. However, the book is particularly aimed at scholars and community members who identify as Black, who are centrally concerned with questions of identity and race in British society. Its Open Access status will facilitate access to the book by all groups in society

Whose Heritage?

This edited collection challenges and re-imagines what is ‘heritage’ in Britain as a globalised, vernacular, cosmopolitan ‘post-nation’. It takes its inspiration from the foundational work of public intellectual Stuart Hall (1932-2014). Hall was instrumental in calling out embedded elitist conceptions of ‘The Heritage’ of Britain. The book’s authors challenge us to reconsider what is valued about Britain’s past, its culture and its citizens. Populist discourses around the world, including Brexit and ‘culture war’ declarations in the UK, demonstrate how heritage and ideas of the past are mobilised in racist politics. The multidisciplinary chapters of this book offer critical inspections of these politics, and dig deeply into the problems of theory, policy and practice in today’s academia, society and heritage sector. The volume challenges the lack of action since Hall rebuked ‘The Heritage’ twenty years ago. The authors featured here are predominantly Black Britons, academics and practitioners engaged in culture and heritage, spurred by the killing of George Floyd and the rise of the Black Lives Matter movement to contest racist practices and structures that support them. The primary audience will be academics, but it will also attract culture sector practitioners and heritage institutions. However, the book is particularly aimed at scholars and community members who identify as Black, who are centrally concerned with questions of identity and race in British society. Its Open Access status will facilitate access to the book by all groups in society

Connecting the dots in classical Hodgkin Lymphoma

Connecting the dots, by integrating data from various domains, including quantitative PET data, serum biomarkers, tumor microenvironment composition, and clinical data this thesis paves the way for more personalized and effective therapeutic strategies for classical Hodgkin Lymphoma (cHL) patients. cHL is characterized by a small percentage of malignant Hodgkin and Reed-Sternberg (HRS) cells within a complex tumor microenvironment abundant in immune cells. Despite this, HRS cells effectively evade immune responses. Diagnosis relies on biopsy and 18F-FDG PET-CT scans, with treatment primarily consisting of risk-stratified chemotherapy and radiotherapy. However, a significant proportion of patients experience primary refractory disease or relapse.Through the research described in this thesis, we identified significant prognostic factors for progression free survival, developed a prognostic model utilizing radiomics PET scan analysis, and synergistically integrated this with serum and genetic biomarkers to enhance prognostic accuracy and treatment decision-making in cHL

Connecting the dots in classical Hodgkin Lymphoma

Connecting the dots, by integrating data from various domains, including quantitative PET data, serum biomarkers, tumor microenvironment composition, and clinical data this thesis paves the way for more personalized and effective therapeutic strategies for classical Hodgkin Lymphoma (cHL) patients. cHL is characterized by a small percentage of malignant Hodgkin and Reed-Sternberg (HRS) cells within a complex tumor microenvironment abundant in immune cells. Despite this, HRS cells effectively evade immune responses. Diagnosis relies on biopsy and 18F-FDG PET-CT scans, with treatment primarily consisting of risk-stratified chemotherapy and radiotherapy. However, a significant proportion of patients experience primary refractory disease or relapse.Through the research described in this thesis, we identified significant prognostic factors for progression free survival, developed a prognostic model utilizing radiomics PET scan analysis, and synergistically integrated this with serum and genetic biomarkers to enhance prognostic accuracy and treatment decision-making in cHL