Measuring Cerebral Activation From fNIRS Signals: An Approach Based on Compressive Sensing and Taylor-Fourier Model

Functional near-infrared spectroscopy (fNIRS) is a noninvasive and portable neuroimaging technique that uses NIR light to monitor cerebral activity by the so-called haemodynamic responses (HRs). The measurement is challenging because of the presence of severe physiological noise, such as respiratory and vasomotor waves. In this paper, a novel technique for fNIRS signal denoising and HR estimation is described. The method relies on a joint application of compressed sensing theory principles and Taylor-Fourier modeling of nonstationary spectral components. It operates in the frequency domain and models physiological noise as a linear combination of sinusoidal tones, characterized in terms of frequency, amplitude, and initial phase. Algorithm performance is assessed over both synthetic and experimental data sets, and compared with that of two reference techniques from fNIRS literature

Techno-economic analysis of residential thermal flexibility for demand side management

The continuing rise in solar and wind production leads to an increasing demand of flexibility to stabilize the electricity grid. Furthermore, we can assume a gradual but intensive rise in the use of electrical heatpumps for household spatial heating, for different reasons. Therefore, this paper investigates the feasibility and viability of entering the flexibility market by aggregating residential thermal loads. For this research, a dataset of 200 dwellings in the Netherlands, equipped with a heatpump and smart metering infrastructure, is analysed. By means of a greybox modeling approach, a thermal model and control framework have been set up for every house, in order to identify the load shift potential and the accompanying cost of providing flexibility for the houses. We find that thermal flexibility is asymmetric: downwards flexibility is, apart from much more dependent on outdoor temperature than upwards flexibility, strictly lower than upwards flexibility. The cost for downwards flexibility is strictly negative in terms of the prosumer. Concerning upwards flexibility, the cost is most of the time positive. Moreover, it can be concluded that there is a potentially viable business case for the flexibility aggregator

Optimal Population Codes for Space: Grid Cells Outperform Place Cells

Rodents use two distinct neuronal coordinate systems to estimate their position: place fields in the hippocampus and grid fields in the entorhinal cortex. Whereas place cells spike at only one particular spatial location, grid cells fire at multiple sites that correspond to the points of an imaginary hexagonal lattice. We study how to best construct place and grid codes, taking the probabilistic nature of neural spiking into account. Which spatial encoding properties of individual neurons confer the highest resolution when decoding the animal’s position from the neuronal population response? A priori, estimating a spatial position from a grid code could be ambiguous, as regular periodic lattices possess translational symmetry. The solution to this problem requires lattices for grid cells with different spacings; the spatial resolution crucially depends on choosing the right ratios of these spacings across the population. We compute the expected error in estimating the position in both the asymptotic limit, using Fisher information, and for low spike counts, using maximum likelihood estimation. Achieving high spatial resolution and covering a large range of space in a grid code leads to a trade-off: the best grid code for spatial resolution is built of nested modules with different spatial periods, one inside the other, whereas maximizing the spatial range requires distinct spatial periods that are pairwisely incommensurate. Optimizing the spatial resolution predicts two grid cell properties that have been experimentally observed. First, short lattice spacings should outnumber long lattice spacings. Second, the grid code should be self-similar across different lattice spacings, so that the grid field always covers a fixed fraction of the lattice period. If these conditions are satisfied and the spatial “tuning curves” for each neuron span the same range of firing rates, then the resolution of the grid code easily exceeds that of the best possible place code with the same number of neurons

Approaching Visual Search in Photo-Realistic Scenes

Visual search is extended from the domain of polygonal figures presented on a uniform background to scenes in which search is for a photo-realistic object in a dense, naturalistic background. Scene generation for these displays relies on a powerful solid modeling program to define the three dimensional forms, surface properties, relative positions, and illumination of the objects and a rendering program to produce an image. Search in the presented experiments is for a rock with specific properties among other, similar rocks, although the method described can be generalized to other situations. Using this technique we explore the effects of illumination and shadows in aiding search for a rock in front of and closer to the viewer than other rocks in the scene. For these scenes, shadows of two different contrast levels can significantly deet·ease reaction times for displays in which target rocks are similar to distractor rocks. However, when the target rock is itself easily distinguishable from dis tractors on the basis of form, the presence or absence of shadows has no discernible effect. To relate our findings to those for earlier polygonal displays, we simplified the non-shadow displays so that only boundary information remained. For these simpler displays, search slopes (the reaction time as a function of the number of distractors) were significantly faster, indicating that the more complex photo-realistic objects require more time to process for visual search. In contrast with several previous experiments involving polygonal figures, we found no evidence for an effect of illumination direction on search times

Effective Stimuli for Constructing Reliable Neuron Models

The rich dynamical nature of neurons poses major conceptual and technical challenges for unraveling their nonlinear membrane properties. Traditionally, various current waveforms have been injected at the soma to probe neuron dynamics, but the rationale for selecting specific stimuli has never been rigorously justified. The present experimental and theoretical study proposes a novel framework, inspired by learning theory, for objectively selecting the stimuli that best unravel the neuron's dynamics. The efficacy of stimuli is assessed in terms of their ability to constrain the parameter space of biophysically detailed conductance-based models that faithfully replicate the neuron's dynamics as attested by their ability to generalize well to the neuron's response to novel experimental stimuli. We used this framework to evaluate a variety of stimuli in different types of cortical neurons, ages and animals. Despite their simplicity, a set of stimuli consisting of step and ramp current pulses outperforms synaptic-like noisy stimuli in revealing the dynamics of these neurons. The general framework that we propose paves a new way for defining, evaluating and standardizing effective electrical probing of neurons and will thus lay the foundation for a much deeper understanding of the electrical nature of these highly sophisticated and non-linear devices and of the neuronal networks that they compose

The Cat Is On the Mat. Or Is It a Dog? Dynamic Competition in Perceptual Decision Making

Recent neurobiological findings suggest that the brain solves simple perceptual decision-making tasks by means of a dynamic competition in which evidence is accumulated in favor of the alternatives. However, it is unclear if and how the same process applies in more complex, real-world tasks, such as the categorization of ambiguous visual scenes and what elements are considered as evidence in this case. Furthermore, dynamic decision models typically consider evidence accumulation as a passive process disregarding the role of active perception strategies. In this paper, we adopt the principles of dynamic competition and active vision for the realization of a biologically- motivated computational model, which we test in a visual catego- rization task. Moreover, our system uses predictive power of the features as the main dimension for both evidence accumulation and the guidance of active vision. Comparison of human and synthetic data in a common experimental setup suggests that the proposed model captures essential aspects of how the brain solves perceptual ambiguities in time. Our results point to the importance of the proposed principles of dynamic competi- tion, parallel specification, and selection of multiple alternatives through prediction, as well as active guidance of perceptual strategies for perceptual decision-making and the resolution of perceptual ambiguities. These principles could apply to both the simple perceptual decision problems studied in neuroscience and the more complex ones addressed by vision research.Peer reviewe