2,748 research outputs found
GPU acceleration of brain image proccessing
Durante los últimos años se ha venido demostrando el alto poder computacional
que ofrecen las GPUs a la hora de resolver determinados problemas.
Al mismo tiempo, existen campos en los que no es posible beneficiarse completamente
de las mejoras conseguidas por los investigadores, debido principalmente
a que los tiempos de ejecución de las aplicaciones llegan a ser extremadamente
largos. Este es por ejemplo el caso del registro de imágenes en medicina.
A pesar de que se han conseguido aceleraciones sobre el registro de imágenes,
su uso en la práctica clínica es aún limitado. Entre otras cosas, esto se debe
al rendimiento conseguido.
Por lo tanto se plantea como objetivo de este proyecto, conseguir mejorar los
tiempos de ejecución de una aplicación dedicada al resgitro de imágenes en medicina,
con el fin de ayudar a aliviar este problema
GPU-based ultra-fast direct aperture optimization for online adaptive radiation therapy
Online adaptive radiation therapy (ART) has great promise to significantly
reduce normal tissue toxicity and/or improve tumor control through real-time
treatment adaptations based on the current patient anatomy. However, the major
technical obstacle for clinical realization of online ART, namely the inability
to achieve real-time efficiency in treatment re-planning, has yet to be solved.
To overcome this challenge, this paper presents our work on the implementation
of an intensity modulated radiation therapy (IMRT) direct aperture optimization
(DAO) algorithm on graphics processing unit (GPU) based on our previous work on
CPU. We formulate the DAO problem as a large-scale convex programming problem,
and use an exact method called column generation approach to deal with its
extremely large dimensionality on GPU. Five 9-field prostate and five 5-field
head-and-neck IMRT clinical cases with 5\times5 mm2 beamlet size and
2.5\times2.5\times2.5 mm3 voxel size were used to evaluate our algorithm on
GPU. It takes only 0.7~2.5 seconds for our implementation to generate optimal
treatment plans using 50 MLC apertures on an NVIDIA Tesla C1060 GPU card. Our
work has therefore solved a major problem in developing ultra-fast
(re-)planning technologies for online ART
Efficient Bayesian-based Multi-View Deconvolution
Light sheet fluorescence microscopy is able to image large specimen with high
resolution by imaging the sam- ples from multiple angles. Multi-view
deconvolution can significantly improve the resolution and contrast of the
images, but its application has been limited due to the large size of the
datasets. Here we present a Bayesian- based derivation of multi-view
deconvolution that drastically improves the convergence time and provide a fast
implementation utilizing graphics hardware.Comment: 48 pages, 20 figures, 1 table, under review at Nature Method
GPU-based Iterative Cone Beam CT Reconstruction Using Tight Frame Regularization
X-ray imaging dose from serial cone-beam CT (CBCT) scans raises a clinical
concern in most image guided radiation therapy procedures. It is the goal of
this paper to develop a fast GPU-based algorithm to reconstruct high quality
CBCT images from undersampled and noisy projection data so as to lower the
imaging dose. For this purpose, we have developed an iterative tight frame (TF)
based CBCT reconstruction algorithm. A condition that a real CBCT image has a
sparse representation under a TF basis is imposed in the iteration process as
regularization to the solution. To speed up the computation, a multi-grid
method is employed. Our GPU implementation has achieved high computational
efficiency and a CBCT image of resolution 512\times512\times70 can be
reconstructed in ~5 min. We have tested our algorithm on a digital NCAT phantom
and a physical Catphan phantom. It is found that our TF-based algorithm is able
to reconstrct CBCT in the context of undersampling and low mAs levels. We have
also quantitatively analyzed the reconstructed CBCT image quality in terms of
modulation-transfer-function and contrast-to-noise ratio under various scanning
conditions. The results confirm the high CBCT image quality obtained from our
TF algorithm. Moreover, our algorithm has also been validated in a real
clinical context using a head-and-neck patient case. Comparisons of the
developed TF algorithm and the current state-of-the-art TV algorithm have also
been made in various cases studied in terms of reconstructed image quality and
computation efficiency.Comment: 24 pages, 8 figures, accepted by Phys. Med. Bio
Development of a GPU-based Monte Carlo dose calculation code for coupled electron-photon transport
Monte Carlo simulation is the most accurate method for absorbed dose
calculations in radiotherapy. Its efficiency still requires improvement for
routine clinical applications, especially for online adaptive radiotherapy. In
this paper, we report our recent development on a GPU-based Monte Carlo dose
calculation code for coupled electron-photon transport. We have implemented the
Dose Planning Method (DPM) Monte Carlo dose calculation package (Sempau et al,
Phys. Med. Biol., 45(2000)2263-2291) on GPU architecture under CUDA platform.
The implementation has been tested with respect to the original sequential DPM
code on CPU in phantoms with water-lung-water or water-bone-water slab
geometry. A 20 MeV mono-energetic electron point source or a 6 MV photon point
source is used in our validation. The results demonstrate adequate accuracy of
our GPU implementation for both electron and photon beams in radiotherapy
energy range. Speed up factors of about 5.0 ~ 6.6 times have been observed,
using an NVIDIA Tesla C1060 GPU card against a 2.27GHz Intel Xeon CPU
processor.Comment: 13 pages, 3 figures, and 1 table. Paper revised. Figures update
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