Fully Integrated Biochip Platforms for Advanced Healthcare

Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring of several human metabolites can be addressed by using fully integrated and minimally invasive devices located in the sub-cutis, typically in the peritoneal region. This extends the techniques of continuous monitoring of glucose currently being pursued with diabetic patients. However, several issues have to be considered in order to succeed in developing fully integrated and minimally invasive implantable devices. These innovative devices require a high-degree of integration, minimal invasive surgery, long-term biocompatibility, security and privacy in data transmission, high reliability, high reproducibility, high specificity, low detection limit and high sensitivity. Recent advances in the field have already proposed possible solutions for several of these issues. The aim of the present paper is to present a broad spectrum of recent results and to propose future directions of development in order to obtain fully implantable systems for the continuous monitoring of the human metabolism in advanced healthcare applications

SciTech News Volume 71, No. 2 (2017)

Columns and Reports From the Editor 3 Division News Science-Technology Division 5 Chemistry Division 8 Engineering Division 9 Aerospace Section of the Engineering Division 12 Architecture, Building Engineering, Construction and Design Section of the Engineering Division 14 Reviews Sci-Tech Book News Reviews 16 Advertisements IEEE

Dynamic Wireless Information and Power Transfer Scheme for Nano-Empowered Vehicular Networks

In this paper, we investigate the wireless power transfer and energy-efficiency (EE) optimization problem for nano-centric vehicular networks operating over the terahertz band. The inbody nano-sensors harvest energy from a power station via radio-frequency signal and then use the harvested energy to transmit data to the sink node. By considering the properties of terahertz band (i.e., sensitivity to distance and frequency over the communication path), we adopt the Brownian motion model to develop a time-variant terahertz channel model and to describe the mobility of the nano-sensors. Thus, based on the channel model and energy resources, we further develop a long-term EE optimization problem. The EE optimization is further converted into a series of energy-efficient resource allocation problems over the time slots via equivalent transformation method. The resource allocation problem for each timeslot, which is formulated as a mixed integer nonlinear programming (MINLP), is solved based on the particle swarm optimization (PSO) method. In addition, a dynamic PSO-based EE optimization (DPEEO) algorithm is developed to obtain the sub-optimal solution for the EE optimization problem. By exploiting the special structure of the reformulated problem, an improved DPEEO algorithm, is presented which can handle the problem’s constraints quite well, decreases the research space, and greatly reduces the length of the convergence time. Simulation results validate the theoretical analysis of our system

Energy Harvesting-Aware Design for Wireless Nanonetworks

Nanotechnology advancement promises to enable a new era of computing and communication devices by shifting micro scale chip design to nano scale chip design. Nanonetworks are envisioned as artifacts of nanotechnology in the domain of networking and communication. These networks will consist of nodes of nanometer to micrometer in size, with a communication range up to 1 meter. These nodes could be used in various biomedical, industrial, and environmental monitoring applications, where a nanoscale level of sensing, monitoring, control and communication is required. The special characteristics of nanonetworks require the revisiting of network design. More specifically, nanoscale limitations, new paradigms of THz communication, and power supply via energy harvesting are the main issues that are not included in traditional network design methods. In this regard, this dissertation investigates and develops some solutions in the realization of nanonetworks. Particularly, the following major solutions are investigated. (I) The energy harvesting and energy consumption processes are modeled and evaluated simultaneously. This model includes the stochastic nature of energy arrival as well as the pulse-based communication model for energy consumption. The model identifies the effect of various parameters in this joint process. (II) Next, an optimization problem is developed to find the best combination of these parameters. Specifically, optimum values for packet size, code weight, and repetition are found in order to minimize the energy consumption while satisfying some application requirements (i.e., delay and reliability). (III) An optimum policy for energy consumption to achieve the maximum utilization of harvested energy is developed. The goal of this scheme is to take advantage of available harvested energy as much as possible while satisfying defined performance metrics. (IV) A communication scheme that tries to maximize the data throughput via a distributed and scalable coordination while avoiding the collision among neighbors is the last problem to be investigated. The goal is to design an energy harvesting-aware and distributed mechanism that could coordinate data transmission among neighbors. (V) Finally, all these solutions are combined together to create a data link layer model for nanonodes. We believe resolving these issues could be the first step towards an energy harvesting-aware network design for wireless nanosensor networks

Optimal Haptic Communications over Nanonetworks for E-Health Systems

A Tactile Internet-based nanonetwork is an emerging field that promises a new range of e-health applications, in which human operators can efficiently operate and control devices at the nanoscale for remote-patient treatment. A haptic feedback is inevitable for establishing a link between the operator and unknown in-body environment. However, haptic communications over the terahertz band may incur significant path loss due to molecular absorption. In this paper, we propose an optimization framework for haptic communications over nanonetworks, in which in-body nanodevices transmit haptic information to an operator via the terahertz band. By considering the properties of the terahertz band, we employ Brownian motion to describe the mobility of the nanodevices and develop a time-variant terahertz channel model. Furthermore, based on the developed channel model, we construct a stochastic optimization problem for improving haptic communications under the constraints of system stability, energy consumption, and latency. To solve the formulated nonconvex stochastic problem, an improved time-varying particle swarm optimization algorithm is presented, which can deal with the constraints of the problem efficiently by reducing the convergence time significantly. The simulation results validate the theoretical analysis of the proposed system

Nanostructured Gas Sensors for Health Care: An Overview

Nanostructured platforms have been utilized for fabrication of small, sensitive and reliable gas sensing devices owing to high functionality, enhanced charge transport and electro-catalytic property. As a result of globalization, rapid, sensitive and selective detection of gases in environment is essential for health care and security. Nonmaterial such as metal, metal oxides, organic polymers, and organic-inorganic hybrid nanocomposites exhibit interesting optical, electrical, magnetic and molecular properties, and hence are found potential gas sensing materials. Morphological, electrical, and optical properties of such nanostructures can be tailored via controlling the precursor concentration and synthesis conditions resulting to achieve desired sensing. This review presents applications of nano-enabling gas sensors to detect gases for environment monitoring. The recent update, challenges, and future vision for commercial applications of such sensor are also described here

Roadmap on quantum nanotechnologies

Quantum phenomena are typically observable at length and time scales smaller than those of our everyday experience, often involving individual particles or excitations. The past few decades have seen a revolution in the ability to structure matter at the nanoscale, and experiments at the single particle level have become commonplace. This has opened wide new avenues for exploring and harnessing quantum mechanical effects in condensed matter. These quantum phenomena, in turn, have the potential to revolutionize the way we communicate, compute and probe the nanoscale world. Here, we review developments in key areas of quantum research in light of the nanotechnologies that enable them, with a view to what the future holds. Materials and devices with nanoscale features are used for quantum metrology and sensing, as building blocks for quantum computing, and as sources and detectors for quantum communication. They enable explorations of quantum behaviour and unconventional states in nano- and opto-mechanical systems, low-dimensional systems, molecular devices, nano-plasmonics, quantum electrodynamics, scanning tunnelling microscopy, and more. This rapidly expanding intersection of nanotechnology and quantum science/technology is mutually beneficial to both fields, laying claim to some of the most exciting scientific leaps of the last decade, with more on the horizon