Software and Hardware Systems for Abdominal Aortic Aneurysm Mechanical Properties Investigation

The main goal of this paper is to describe two different systems that were developed for the purpose of abdominal aortic aneurysm mechanical properties investigation and to present the results of the measurements. The first system is based on the "Bubble Inflated" method and it increases the pressure of physiological saline which affects blood vessel tissue and causes mechanical deformation. The system provides recording the data about the current value of the pressure in the physiological saline by using the appropriate pressure sensor. The second system makes stretches of the vessel tissue in uni-axial direction and save the data about the force and the elongation. Both of these systems use cameras for assessment of the deformation. Obtained results from both systems are used for numerical simulation of computer model for abdominal aortic aneurysm. It gives a new avenue for application of software and hardware systems for determination of vascular tissue properties in the clinical practice

AsmetaF: A Flattener for the ASMETA Framework

Abstract State Machines (ASMs) have shown to be a suitable high-level specification method for complex, even industrial, systems; the ASMETA framework, supporting several validation and verification activities on ASM models, is an example of a formal integrated development environment. Although ASMs allow modeling complex systems in a rather concise way -and this is advantageous for specification purposes-, such concise notation is in general a problem for verification activities as model checking and theorem proving that rely on tools accepting simpler notations. In this paper, we propose a flattener tool integrated in the ASMETA framework that transforms a general ASM model in a flattened model constituted only of update, parallel, and conditional rules; such model is easier to map to notations of verification tools. Experiments show the effect of applying the tool to some representative case studies of the ASMETA repository.Comment: In Proceedings F-IDE 2018, arXiv:1811.09014. The first two authors are supported by ERATO HASUO Metamathematics for Systems Design Project (No. JPMJER1603), JST. Funding Reference number: 10.13039/501100009024 ERAT

Petrology and Geochemistry of Serpentinites Associated with the Ultra-High Pressure Lago di Cignana Unit (ItalianWestern Alps)

In the Western Alps, the ophiolitic Zermatt–Saas Zone (ZSZ) and the Lago di Cignana Unit (LCU) record oceanic lithosphere subduction to high (540°C, 2·3GPa) and ultra-high pressure (600°C, 3·2GPa), respectively. The top of the Zermatt–Saas Zone in contact with the Lago di Cignana Unit consists of olivine þ Ti-clinohumite-bearing serpentinites (the Cignana serpentinite) hosting olivine þ Ti-clinohumite veins and dykelets of olivine þ Ti-chondrodite þ Ti-clinohumite. The composition of this serpentinite reveals a refertilized oceanic mantle peridotite protolith that became subsequently enriched in fluid-mobile elements (FME) during oceanic serpentinization. The olivine þ Ti-clinohumite veins in the Cignana serpentinite display Rare Earth Element (REE) and FME compositions quite similar to the host-rock, which suggests closed-system dehydration of this serpentinite during subduction. The Ti-chondrodite-bearing dykelets are richer in REE and FME than the host-rock and the dehydration olivine þ Ti-clinohumite veins: their Nd composition points to a mafic protolith, successively overprinted by oceanic metasomatism and by subduction zone recrystallization. These dykelets are comparable in composition to eclogites within the ultra-high pressure LCU that derive from subducted oceanic mafic crust. Different from the LCU, serpentinites from the core domains of the ZSZ display REE compositions indicating a depleted mantle protolith. The oceanic serpentinization of these rocks led to an increase in FME and to seawater-like Sr isotope compositions. The serpentinites sampled at increasing distance from the ultra-high pressure LCU reveal different mantle protoliths, still preserve an oceanic geochemical imprint and contain mafic dykelets affected by oceanic metasomatism. The subduction zone history of these rocks thus occurred under relatively closed system conditions, the only possible change during subduction being an enrichment in As and Sb recorded by the serpentinites closer to the crustal LCU. The ZSZ and Cignana serpentinites thus likely evolved in a slab setting and were weakly exposed to interaction with slab-derived fluids characteristic of plate interface settings. Our data suggest two possible scenarios for the evolution of the studied ZSZ and Cignana serpentinites. They are either part of a coherent ophiolite unit whose initial lithospheric mantle was variably affected by depletion and re-fertilization processes, or they belong to separate tectonic slices derived from two different oceanic mantle sections. In the Cignana serpentinite atop the ZSZ, the presence of Ti-chondrodite dykelets similar in composition to the LCU eclogites suggests these two domains were closely associated in the oceanic lithosphere and shared the same evolution to ultra-high pressure conditions during Alpine subduction

Translating concurrent RSL into PVS

Translating RSL into PVS has been a way of obtaining a proof tool for RSL. However there are several styles or constructs of RSL that are harder to translate than others. One of them is concurrent RSL since PVS has no similar construct. We propose to study the problems involved in translating Concurrent RSL into PVS.Eje: Ingeniería de SoftwareRed de Universidades con Carreras en Informática (RedUNCI

The water and fluid-mobile element cycles during serpentinite subduction. A review

The key role of serpentinites in the global cycles of volatiles, halogens and fluid-mobile elements in oceans and in subduction zones is now ascertained by many studies quantifying their element budgets and the composition of fluids they release during subduction. Geochemical tracers (e.g. B, As, Sb; stable B and radiogenic Sr and Pb isotopes) have also been employed to trace the provenance of serpentinites (slab or forearc mantle?) accreted to the plate interface of fossil subduction zones. In turn, this helps defining the tectonic processes, seismicity and mass transfer attending rock burial and exhumation within subduction zones. The results suggest that the sole use of geochemical data is insufficient to track the origin of subduction-zone serpentinites and the timing of serpentinization, whether oceanic or subduction-related. Integrated multidisciplinary studies of ophiolitic serpentinite show that pristine, oceanic, geochemical imprints (e.g. high 11B, marine Sr isotopes, low As + Sb) become reset towards more radiogenic Sr, lower 11B, and higher As + Sb via metasomatic exchange with crust-derived fluids during subduction accretion to the plate interface.The dehydration fluids released by serpentinite dehydration at various subduction stages and still preserved in these rocks as inclusions, carry significant amounts of halogens and fluid-mobile elements. The key compositional similarities of antigorite-breakdown fluids from different localities (Betic Cordillera, Spain; Central Alps, Switzerland) indicate that rocks record comparable subduction processes. We individuate the fluid-mediated exchange with sedimentary and/or crustal reservoirs during subduction as the key mechanism for geochemical hybridization of serpentinite. The antigorite dehydration fluids produced by hybrid serpentinites have high Cs, Rb, Ba, B, Pb, As, Sb and Li overlapping those of the arc lavas and representing the mixed serpentinite\u2013sediment (crustal) component released to arcs. This helps discriminating the mass transfer processes responsible for supra-subduction mantle metasomatism and arc magmatism. The studied plate-interface hybrid serpentinites are also proxies of forearc mantle metasomatized by slab fluids. Based on the above observations, we propose that the mass transfer from slabs to plate interface and/or forearc mantle and the subsequent down-drag of this altered mantle to subarc depths potentially is a major process operating in subduction zones.The nominally anhydrous olivine, orhopyroxene, clinopyroxene and garnet produced by serpentinite dehydration host appreciable amounts of halogens and fluid-mobile elements that can be recycled in the deep mantle beyond arcs. Involvement of de-serpentinized residues in lower mantle metasomatism begins to be increasingly recognized by studies of ocean island basalts (OIB) and of B-bearing blue diamonds and by the isotopic serpentinite compositions presented here

Data refinement for true concurrency

The majority of modern systems exhibit sophisticated concurrent behaviour, where several system components modify and observe the system state with fine-grained atomicity. Many systems (e.g., multi-core processors, real-time controllers) also exhibit truly concurrent behaviour, where multiple events can occur simultaneously. This paper presents data refinement defined in terms of an interval-based framework, which includes high-level operators that capture non-deterministic expression evaluation. By modifying the type of an interval, our theory may be specialised to cover data refinement of both discrete and continuous systems. We present an interval-based encoding of forward simulation, then prove that our forward simulation rule is sound with respect to our data refinement definition. A number of rules for decomposing forward simulation proofs over both sequential and parallel composition are developed

Seismic vulnerability of building aggregates through hybrid and indirect assessment techniques

This work approaches the seismic vulnerability assessment of an old stone masonry building aggregate, located in San Pio delle Camere (Abruzzo, Italy), slightly affected by the 2009 April 6th earthquake occurred in L’Aquila and its districts. This building aggregate has been modelled by using the 3muri software for seismic analysis of masonry constructions. On one hand, static non-linear numerical analyses were performed to obtain capacity curves together with the prediction of damage distributions for the input seismic action (hybrid technique). On the other hand, indirect techniques, based on different vulnerability index formulations, were used for assessing the building aggregate’s behaviour under earthquake action. The activities carried out have provided a clear framework on the seismic vulnerability of building aggregates, as well as aid future retrofitting interventions

An open extensible tool environment for Event-B

Abstract. We consider modelling indispensable for the development of complex systems. Modelling must be carried out in a formal notation to reason and make meaningful conjectures about a model. But formal modelling of complex systems is a difficult task. Even when theorem provers improve further and get more powerful, modelling will remain difficult. The reason for this that modelling is an exploratory activity that requires ingenuity in order to arrive at a meaningful model. We are aware that automated theorem provers can discharge most of the onerous trivial proof obligations that appear when modelling systems. In this article we present a modelling tool that seamlessly integrates modelling and proving similar to what is offered today in modern integrated development environments for programming. The tool is extensible and configurable so that it can be adapted more easily to different application domains and development methods.