2,988 research outputs found

    An Overview of the Use of Neural Networks for Data Mining Tasks

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    In the recent years the area of data mining has experienced a considerable demand for technologies that extract knowledge from large and complex data sources. There is a substantial commercial interest as well as research investigations in the area that aim to develop new and improved approaches for extracting information, relationships, and patterns from datasets. Artificial Neural Networks (NN) are popular biologically inspired intelligent methodologies, whose classification, prediction and pattern recognition capabilities have been utilised successfully in many areas, including science, engineering, medicine, business, banking, telecommunication, and many other fields. This paper highlights from a data mining perspective the implementation of NN, using supervised and unsupervised learning, for pattern recognition, classification, prediction and cluster analysis, and focuses the discussion on their usage in bioinformatics and financial data analysis tasks

    Using rule extraction to improve the comprehensibility of predictive models.

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    Whereas newer machine learning techniques, like artifficial neural net-works and support vector machines, have shown superior performance in various benchmarking studies, the application of these techniques remains largely restricted to research environments. A more widespread adoption of these techniques is foiled by their lack of explanation capability which is required in some application areas, like medical diagnosis or credit scoring. To overcome this restriction, various algorithms have been proposed to extract a meaningful description of the underlying `blackbox' models. These algorithms' dual goal is to mimic the behavior of the black box as closely as possible while at the same time they have to ensure that the extracted description is maximally comprehensible. In this research report, we first develop a formal definition of`rule extraction and comment on the inherent trade-off between accuracy and comprehensibility. Afterwards, we develop a taxonomy by which rule extraction algorithms can be classiffied and discuss some criteria by which these algorithms can be evaluated. Finally, an in-depth review of the most important algorithms is given.This report is concluded by pointing out some general shortcomings of existing techniques and opportunities for future research.Models; Model; Algorithms; Criteria; Opportunities; Research; Learning; Neural networks; Networks; Performance; Benchmarking; Studies; Area; Credit; Credit scoring; Behavior; Time;

    Ontology Enrichment from Free-text Clinical Documents: A Comparison of Alternative Approaches

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    While the biomedical informatics community widely acknowledges the utility of domain ontologies, there remain many barriers to their effective use. One important requirement of domain ontologies is that they achieve a high degree of coverage of the domain concepts and concept relationships. However, the development of these ontologies is typically a manual, time-consuming, and often error-prone process. Limited resources result in missing concepts and relationships, as well as difficulty in updating the ontology as domain knowledge changes. Methodologies developed in the fields of Natural Language Processing (NLP), Information Extraction (IE), Information Retrieval (IR), and Machine Learning (ML) provide techniques for automating the enrichment of ontology from free-text documents. In this dissertation, I extended these methodologies into biomedical ontology development. First, I reviewed existing methodologies and systems developed in the fields of NLP, IR, and IE, and discussed how existing methods can benefit the development of biomedical ontologies. This previously unconducted review was published in the Journal of Biomedical Informatics. Second, I compared the effectiveness of three methods from two different approaches, the symbolic (the Hearst method) and the statistical (the Church and Lin methods), using clinical free-text documents. Third, I developed a methodological framework for Ontology Learning (OL) evaluation and comparison. This framework permits evaluation of the two types of OL approaches that include three OL methods. The significance of this work is as follows: 1) The results from the comparative study showed the potential of these methods for biomedical ontology enrichment. For the two targeted domains (NCIT and RadLex), the Hearst method revealed an average of 21% and 11% new concept acceptance rates, respectively. The Lin method produced a 74% acceptance rate for NCIT; the Church method, 53%. As a result of this study (published in the Journal of Methods of Information in Medicine), many suggested candidates have been incorporated into the NCIT; 2) The evaluation framework is flexible and general enough that it can analyze the performance of ontology enrichment methods for many domains, thus expediting the process of automation and minimizing the likelihood that key concepts and relationships would be missed as domain knowledge evolves

    Application based technical Approaches of data mining in Pharmaceuticals, and Research approaches in biomedical and Bioinformatics

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    In the past study shows that flow of direction in the field of pharmaceutical was quit slow and simplest and by the time the process of transformation of information was so complex and the it was out of the reach to the technology, new modern technology could not reach to catch the pharmaceutical field. Then the later on technology becomes the compulsorily part of business and its contributed into business progress and developments. But now a days its get technology enabled and smoothly and easily pharma industries managing their billings and inventories and developing new products and services and now its easy to maintain and merging the drugs detail like its cost ,and usage with the patients records prescribe by the doctors in the hospitals .and data collection methods have improved data manipulation techniques are yet to keep pace with them data mining called and refer with the specific term as pattern analysis on large data sets used like clustering, segmentation and classification for helping better manipulation of the data and hence it helps to the pharma firms and industries this paper describes the vital role of data Mining in the pharma industry and thus data mining improves the quality of decision making services in pharmaceutical fields. This paper also describe a brief overviews of tool kits of Data mining and its various Applications in the field of Biomedical research in terms of relational approaches of data minings with the Emphasis on propositionalisation and relational subgroup discovery, and which is quit helpful to prove to be effective for data analysis in biomedical and its applications and in Bioinformatics as well. DOI: 10.17762/ijritcc2321-8169.15038
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