Explicit Non-Adaptive Combinatorial Group Testing Schemes

Group testing is a long studied problem in combinatorics: A small set of $r$ ill people should be identified out of the whole ($n$ people) by using only queries (tests) of the form "Does set X contain an ill human?". In this paper we provide an explicit construction of a testing scheme which is better (smaller) than any known explicit construction. This scheme has \bigT{\min[r^2 \ln n,n]} tests which is as many as the best non-explicit schemes have. In our construction we use a fact that may have a value by its own right: Linear error-correction codes with parameters $[m,k,\delta m]_q$ meeting the Gilbert-Varshamov bound may be constructed quite efficiently, in \bigT{q^km} time.Comment: 15 pages, accepted to ICALP 200

Derandomization and Group Testing

The rapid development of derandomization theory, which is a fundamental area in theoretical computer science, has recently led to many surprising applications outside its initial intention. We will review some recent such developments related to combinatorial group testing. In its most basic setting, the aim of group testing is to identify a set of "positive" individuals in a population of items by taking groups of items and asking whether there is a positive in each group. In particular, we will discuss explicit constructions of optimal or nearly-optimal group testing schemes using "randomness-conducting" functions. Among such developments are constructions of error-correcting group testing schemes using randomness extractors and condensers, as well as threshold group testing schemes from lossless condensers.Comment: Invited Paper in Proceedings of 48th Annual Allerton Conference on Communication, Control, and Computing, 201

Construction of Almost Disjunct Matrices for Group Testing

In a \emph{group testing} scheme, a set of tests is designed to identify a small number $t$ of defective items among a large set (of size $N$) of items. In the non-adaptive scenario the set of tests has to be designed in one-shot. In this setting, designing a testing scheme is equivalent to the construction of a \emph{disjunct matrix}, an $M \times N$ matrix where the union of supports of any $t$ columns does not contain the support of any other column. In principle, one wants to have such a matrix with minimum possible number $M$ of rows (tests). One of the main ways of constructing disjunct matrices relies on \emph{constant weight error-correcting codes} and their \emph{minimum distance}. In this paper, we consider a relaxed definition of a disjunct matrix known as \emph{almost disjunct matrix}. This concept is also studied under the name of \emph{weakly separated design} in the literature. The relaxed definition allows one to come up with group testing schemes where a close-to-one fraction of all possible sets of defective items are identifiable. Our main contribution is twofold. First, we go beyond the minimum distance analysis and connect the \emph{average distance} of a constant weight code to the parameters of an almost disjunct matrix constructed from it. Our second contribution is to explicitly construct almost disjunct matrices based on our average distance analysis, that have much smaller number of rows than any previous explicit construction of disjunct matrices. The parameters of our construction can be varied to cover a large range of relations for $t$ and $N$.Comment: 15 Page

Efficiently Decodable Non-Adaptive Threshold Group Testing

We consider non-adaptive threshold group testing for identification of up to $d$ defective items in a set of $n$ items, where a test is positive if it contains at least $2 \leq u \leq d$ defective items, and negative otherwise. The defective items can be identified using $t = O \left( \left( \frac{d}{u} \right)^u \left( \frac{d}{d - u} \right)^{d-u} \left(u \log{\frac{d}{u}} + \log{\frac{1}{\epsilon}} \right) \cdot d^2 \log{n} \right)$ tests with probability at least $1 - \epsilon$ for any $\epsilon > 0$ or $t = O \left( \left( \frac{d}{u} \right)^u \left( \frac{d}{d -u} \right)^{d - u} d^3 \log{n} \cdot \log{\frac{n}{d}} \right)$ tests with probability 1. The decoding time is $t \times \mathrm{poly}(d^2 \log{n})$. This result significantly improves the best known results for decoding non-adaptive threshold group testing: $O(n\log{n} + n \log{\frac{1}{\epsilon}})$ for probabilistic decoding, where $\epsilon > 0$, and $O(n^u \log{n})$ for deterministic decoding

A framework for generalized group testing with inhibitors and its potential application in neuroscience

The main goal of group testing with inhibitors (GTI) is to efficiently identify a small number of defective items and inhibitor items in a large set of items. A test on a subset of items is positive if the subset satisfies some specific properties. Inhibitor items cancel the effects of defective items, which often make the outcome of a test containing defective items negative. Different GTI models can be formulated by considering how specific properties have different cancellation effects. This work introduces generalized GTI (GGTI) in which a new type of items is added, i.e., hybrid items. A hybrid item plays the roles of both defectives items and inhibitor items. Since the number of instances of GGTI is large (more than 7 million), we introduce a framework for classifying all types of items non-adaptively, i.e., all tests are designed in advance. We then explain how GGTI can be used to classify neurons in neuroscience. Finally, we show how to realize our proposed scheme in practice

Superselectors: Efficient Constructions and Applications

We introduce a new combinatorial structure: the superselector. We show that superselectors subsume several important combinatorial structures used in the past few years to solve problems in group testing, compressed sensing, multi-channel conflict resolution and data security. We prove close upper and lower bounds on the size of superselectors and we provide efficient algorithms for their constructions. Albeit our bounds are very general, when they are instantiated on the combinatorial structures that are particular cases of superselectors (e.g., (p,k,n)-selectors, (d,\ell)-list-disjunct matrices, MUT_k(r)-families, FUT(k, a)-families, etc.) they match the best known bounds in terms of size of the structures (the relevant parameter in the applications). For appropriate values of parameters, our results also provide the first efficient deterministic algorithms for the construction of such structures