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An end-to-end framework for real-time automatic sleep stage classification.
Sleep staging is a fundamental but time consuming process in any sleep laboratory. To greatly speed up sleep staging without compromising accuracy, we developed a novel framework for performing real-time automatic sleep stage classification. The client-server architecture adopted here provides an end-to-end solution for anonymizing and efficiently transporting polysomnography data from the client to the server and for receiving sleep stages in an interoperable fashion. The framework intelligently partitions the sleep staging task between the client and server in a way that multiple low-end clients can work with one server, and can be deployed both locally as well as over the cloud. The framework was tested on four datasets comprising ≈1700 polysomnography records (≈12000 hr of recordings) collected from adolescents, young, and old adults, involving healthy persons as well as those with medical conditions. We used two independent validation datasets: one comprising patients from a sleep disorders clinic and the other incorporating patients with Parkinson's disease. Using this system, an entire night's sleep was staged with an accuracy on par with expert human scorers but much faster (≈5 s compared with 30-60 min). To illustrate the utility of such real-time sleep staging, we used it to facilitate the automatic delivery of acoustic stimuli at targeted phase of slow-sleep oscillations to enhance slow-wave sleep
Sleep Analytics and Online Selective Anomaly Detection
We introduce a new problem, the Online Selective Anomaly Detection (OSAD), to
model a specific scenario emerging from research in sleep science. Scientists
have segmented sleep into several stages and stage two is characterized by two
patterns (or anomalies) in the EEG time series recorded on sleep subjects.
These two patterns are sleep spindle (SS) and K-complex. The OSAD problem was
introduced to design a residual system, where all anomalies (known and unknown)
are detected but the system only triggers an alarm when non-SS anomalies
appear. The solution of the OSAD problem required us to combine techniques from
both machine learning and control theory. Experiments on data from real
subjects attest to the effectiveness of our approach.Comment: Submitted to 20th ACM SIGKDD Conference on Knowledge Discovery and
Data Mining 201
Deep Convolutional Neural Networks for Interpretable Analysis of EEG Sleep Stage Scoring
Sleep studies are important for diagnosing sleep disorders such as insomnia,
narcolepsy or sleep apnea. They rely on manual scoring of sleep stages from raw
polisomnography signals, which is a tedious visual task requiring the workload
of highly trained professionals. Consequently, research efforts to purse for an
automatic stage scoring based on machine learning techniques have been carried
out over the last years. In this work, we resort to multitaper spectral
analysis to create visually interpretable images of sleep patterns from EEG
signals as inputs to a deep convolutional network trained to solve visual
recognition tasks. As a working example of transfer learning, a system able to
accurately classify sleep stages in new unseen patients is presented.
Evaluations in a widely-used publicly available dataset favourably compare to
state-of-the-art results, while providing a framework for visual interpretation
of outcomes.Comment: 8 pages, 1 figure, 2 tables, IEEE 2017 International Workshop on
Machine Learning for Signal Processin
EEG sleep stages identification based on weighted undirected complex networks
Sleep scoring is important in sleep research because any errors in the scoring of the patient's sleep electroencephalography (EEG) recordings can cause serious problems such as incorrect diagnosis, medication errors, and misinterpretations of patient's EEG recordings. The aim of this research is to develop a new automatic method for EEG sleep stages classification based on a statistical model and weighted brain networks.
Methods
each EEG segment is partitioned into a number of blocks using a sliding window technique. A set of statistical features are extracted from each block. As a result, a vector of features is obtained to represent each EEG segment. Then, the vector of features is mapped into a weighted undirected network. Different structural and spectral attributes of the networks are extracted and forwarded to a least square support vector machine (LS-SVM) classifier. At the same time the network's attributes are also thoroughly investigated. It is found that the network's characteristics vary with their sleep stages. Each sleep stage is best represented using the key features of their networks.
Results
In this paper, the proposed method is evaluated using two datasets acquired from different channels of EEG (Pz-Oz and C3-A2) according to the R&K and the AASM without pre-processing the original EEG data. The obtained results by the LS-SVM are compared with those by Naïve, k-nearest and a multi-class-SVM. The proposed method is also compared with other benchmark sleep stages classification methods. The comparison results demonstrate that the proposed method has an advantage in scoring sleep stages based on single channel EEG signals.
Conclusions
An average accuracy of 96.74% is obtained with the C3-A2 channel according to the AASM standard, and 96% with the Pz-Oz channel based on the R&K standard
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