Process-based Software Tweaking with Mobile Agents

We describe an approach based upon software process technology to on-the-fly monitoring, redeployment, reconfiguration, and in general adaptation of distributed software applications, in short 'software tweaking'. We choose the term tweaking to refer to modifications in structure and behavior that can be made to individual components, as well as sets thereof, or the overall target system configuration, such as adding, removing or substituting components, while the system is running and without bringing it down. The goal of software tweaking is manifold: supporting run-time software composition, enforcing adherence to requirements, ensuring uptime and quality of service of mission-critical systems, recovering from and preventing faults, seamless system upgrading, etc. Our approach involves dispatching and coordinating software agents - named Worklets - via a process engine, since successful tweaking of a complex distributed software system often requires the concerted action of multiple agents on multiple components. The software tweaking process must incorporate and decide upon knowledge about the specifications and architecture of the target software, as well as Worklets capabilities. Software tweaking is correlated to a variety of other software processes - such as configuration management, deployment, validation and evolution - and allows to address at run time a number of related concerns that are normally dealt with only at development time

In Silico medicine: Social, Technological and Symbolic Mediation

In silico medicine is still forging a road for itself in the current biomedical landscape. Discursively and rhetorically, it is using a three-way positioning, first, deploying discourses of personalised medicine, second, extending the 3Rs from animal to clinical research, and third, aligning its methods with experimental methods. The discursive and rhetorical positioning in promotions and statements of the programme gives us insight into the sociability of the scientific labour of advancing the programme. Its progress depends on complex social, institutional and technological conditions which are not external to its epistemology, but intricately interwoven with it. This article sets out to show that this is the case through an analysis of the process of computational modelling that is at the core of its epistemology. In this paper I show that the very notion of ‘model’ needs to be re-thought for in silico medicine (as indeed, for most forms of computational modelling), and propose a replacement, in the form of the ‘Model-Simulation-Experiment-System’ or MSE-system, which is simultaneously an epistemological, social and technological system. I argue that the MSE-system is radically mediated by social relations, technologies and symbolic systems. We need now to understand how such mediations operate effectively in the construction of robust MSE-systems. keywords: system medicine, philosophy of modeling and simulation, technological mediation

A Model-Based Approach Towards the Conceptualization of Digital Twins: The Case of the EU-Project COGITO

In agile business ecosystems, digitalization is a key enabler for agility and flexibility. However, digital transformation is often challenging for instance due to unclear definitions and a lack of problem understanding. In this work this complexity is addressed with a model-based approach for conceptualizing digitalization and related meta modelling activities to enable the conceptual integration of diverse concepts. Existing modelling approaches – BPMN and ArchiMate – are leveraged with domain specific considerations that are relevant for the digitalization. The construction use case from the European project COGITO serves as a foundation for ideation and first requirements engineering. Physical experiments in the OMiLAB Innovation Environment are used as an experimental method towards identifying relevant digital twinning concepts, while modelling methods can be seen as an integration platform for physical and digital elements. Key digitalization aspects towards digital twinning are discussed and conceptualized in a meta model

Theory and Practice of Data Citation

Citations are the cornerstone of knowledge propagation and the primary means of assessing the quality of research, as well as directing investments in science. Science is increasingly becoming "data-intensive", where large volumes of data are collected and analyzed to discover complex patterns through simulations and experiments, and most scientific reference works have been replaced by online curated datasets. Yet, given a dataset, there is no quantitative, consistent and established way of knowing how it has been used over time, who contributed to its curation, what results have been yielded or what value it has. The development of a theory and practice of data citation is fundamental for considering data as first-class research objects with the same relevance and centrality of traditional scientific products. Many works in recent years have discussed data citation from different viewpoints: illustrating why data citation is needed, defining the principles and outlining recommendations for data citation systems, and providing computational methods for addressing specific issues of data citation. The current panorama is many-faceted and an overall view that brings together diverse aspects of this topic is still missing. Therefore, this paper aims to describe the lay of the land for data citation, both from the theoretical (the why and what) and the practical (the how) angle.Comment: 24 pages, 2 tables, pre-print accepted in Journal of the Association for Information Science and Technology (JASIST), 201

From A to Z: Wearable technology explained

Wearable technology (WT) has become a viable means to provide low-cost clinically sensitive data for more informed patient assessment. The benefit of WT seems obvious: small, worn discreetly in any environment, personalised data and possible integration into communication networks, facilitating remote monitoring. Yet, WT remains poorly understood and technology innovation often exceeds pragmatic clinical demand and use. Here, we provide an overview of the common challenges facing WT if it is to transition from novel gadget to an efficient, valid and reliable clinical tool for modern medicine. For simplicity, an A–Z guide is presented, focusing on key terms, aiming to provide a grounded and broad understanding of current WT developments in healthcare

Coordinative Entities: Forms of Organizing in Data Intensive Science

Scientific collaboration is a long-standing subject of CSCW scholarship that typically focuses on the development and use of computing systems to facilitate research. The research presented in this article investigates the sociality of science by identifying and describing particular, common forms of organizing that researchers in four different scientific realms employ to conduct work in both local contexts and as part of distributed, global projects. This paper introduces five prototypical forms of organizing we categorize as coordinative entities: the Principal Group, Intermittent Exchange, Sustained Aggregation, Federation, and Facility Organization. Coordinative entities as a categorization help specify, articulate, compare, and trace overlapping and evolving arrangements scientists use to facilitate data intensive research. We use this typology to unpack complexities of data intensive scientific collaboration in four cases, showing how scientists invoke different coordinative entities across three types of research activities: data collection, processing, and analysis. Our contribution scrutinizes the sociality of scientific work to illustrate how these actors engage in relational work within and among diverse, dispersed forms of organizing across project, funding, and disciplinary boundaries