25 research outputs found
Enhanced Fractal Image Coding (FIC) with Collage and Reconstruction Residuals
In this paper, two new paradigms are proposed with fractal collage and reconstruction residuals to enhance FIC. In the first new paradigm, FIC is optimized using the reconstruction residuals. In the second paradigm, the selected collage residuals are used to correct the iterated function system (IFS) of FIC, and an effective technique for coding the selected collage residuals is applied based on DCT and embedded bit-plane coding. In the first paradigm, the reconstruction quality is improved without increasing the bit rate. Using the second paradigm, we can improve the reconstruction quality with a little bit (about 0.01 bpp) increase in bit rate. Experimental results show that the proposed paradigms achieve better performance than JPEG at lower bit rate and similar performance at higher bit rate
Space and Earth Sciences, Computer Systems, and Scientific Data Analysis Support, Volume 1
This Final Progress Report covers the specific technical activities of Hughes STX Corporation for the last contract triannual period of 1 June through 30 Sep. 1993, in support of assigned task activities at Goddard Space Flight Center (GSFC). It also provides a brief summary of work throughout the contract period of performance on each active task. Technical activity is presented in Volume 1, while financial and level-of-effort data is presented in Volume 2. Technical support was provided to all Division and Laboratories of Goddard's Space Sciences and Earth Sciences Directorates. Types of support include: scientific programming, systems programming, computer management, mission planning, scientific investigation, data analysis, data processing, data base creation and maintenance, instrumentation development, and management services. Mission and instruments supported include: ROSAT, Astro-D, BBXRT, XTE, AXAF, GRO, COBE, WIND, UIT, SMM, STIS, HEIDI, DE, URAP, CRRES, Voyagers, ISEE, San Marco, LAGEOS, TOPEX/Poseidon, Pioneer-Venus, Galileo, Cassini, Nimbus-7/TOMS, Meteor-3/TOMS, FIFE, BOREAS, TRMM, AVHRR, and Landsat. Accomplishments include: development of computing programs for mission science and data analysis, supercomputer applications support, computer network support, computational upgrades for data archival and analysis centers, end-to-end management for mission data flow, scientific modeling and results in the fields of space and Earth physics, planning and design of GSFC VO DAAC and VO IMS, fabrication, assembly, and testing of mission instrumentation, and design of mission operations center
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In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation.
Regulatory T cells (Tregs) have been shown to be critical in the balance between autoimmunity and tolerance and have been implicated in several human autoimmune diseases. However, the small number of Tregs in peripheral blood limits their therapeutic potential. Therefore, we developed a protocol that would allow for the expansion of Tregs while retaining their suppressive activity. We isolated CD4+CD25 hi cells from human peripheral blood and expanded them in vitro in the presence of anti-CD3 and anti-CD28 magnetic Xcyte Dynabeads and high concentrations of exogenous Interleukin (IL)-2. Tregs were effectively expanded up to 200-fold while maintaining surface expression of CD25 and other markers of Tregs: CD62L, HLA-DR, CCR6, and FOXP3. The expanded Tregs suppressed proliferation and cytokine secretion of responder PBMCs in co-cultures stimulated with anti-CD3 or alloantigen. Treg expansion is a critical first step before consideration of Tregs as a therapeutic intervention in patients with autoimmune or graft-versus-host disease
Technology 2003: Conference Proceedings from the Fourth National Technology Transfer Conference and Exposition, Volume 1
Proceedings from symposia of the Technology 2003 Conference and Exposition, December 7-9, I993, Anaheim, CA. Volume 1 features the Plenary Session and the Plenary Workshop, plus papers presented in Advanced Manufacturing, Biotechnology/Medical Technology, Environmental Technology, Materials Science, and Power and Energy