Forms of organizing: What is new and why?

This paper aims to further our understanding of new forms of organizing by asking and answering two related questions: What is new in forms of organizing? and Why is it so? It starts by examining the main forces that lead to the emergence and diffusion of new organizational arrangements, distinguishing between objective and subjective factors and pointing out the interplay between the two. Elaborating on these two groups of factors, the paper introduces two dimensions ‹flexibility and openness‹ on which a contingency analysis of new forms of organizing and a classification are built. Flexibility is associated with the question «How fast does the organization as a whole have to learn?», while openness is intended to measure the need for knowledge integration and the location of relevant knowledge. Having outlined the main trends in the development of organizational arrangements, the paper looks at some of the implications. The use of information and communication technologies, knowledge management, changes in human resource practices and social contract, and changes in management roles and careers are all seen as consequences of a new quest for openness and flexibility. All these considerations lead to the conclusion that, nowadays, changes in organizational patterns are radical, calling for a paradigm change that will facilitate, in a holistic manner, the adjustments that are needed in order to build and manage these organizations. Like any paradigm change, this requires a change in the mindset of the agents involved, especially the decision-makers.new forms of organizing; new organizational arrangements;

Arguments for a "U.S. Kamioka": SNOLab and its Implications for North American Underground Science Planning

We argue for a cost-effective, long-term North American underground science strategy based on partnership with Canada and initial construction of a modest U.S. Stage I laboratory designed to complement SNOLab. We show, by reviewing the requirements of detectors now in the R&D phase, that SNOLab and a properly designed U.S. Stage I facility would be capable of meeting the needs of North America's next wave of underground experiments. We discuss one opportunity for creating a Stage I laboratory, the Pioneer tunnel in Washington State, a site that could be developed to provide dedicated, clean, horizontal access. This unused tunnel, part of the deepest (1040 m) tunnel system in the U.S., would allow the U.S. to establish, at low risk and low cost, a laboratory at a depth (2.12 km.w.e., or kilometers of water equivalent) quite similar to that of the Japanese laboratory Kamioka (2.04 km.w.e.). We describe studies of cosmic ray attenuation important to properly locating such a laboratory, and the tunnel improvements that would be required to produce an optimal Stage I facility. We also discuss possibilities for far-future Stage II (3.62 km.w.e.) and Stage III (5.00 km.w.e.) developments at the Pioneer tunnel, should future North American needs for deep space exceed that available at SNOLab.Comment: 23 pages, 10 figures; revised version includes discusion about neutrino-factory magic baseline

Resolving branched DNA intermediates with structure-specific nucleases during replication in eukaryotes

Genome duplication requires that replication forks track the entire length of every chromosome. When complications occur, homologous recombination-mediated repair supports replication fork movement and recovery. This leads to physical connections between the nascent sister chromatids in the form of Holliday junctions and other branched DNA intermediates. A key role in the removal of these recombination intermediates falls to structure-specific nucleases such as the Holliday junction resolvase RuvC in Escherichia coli. RuvC is also known to cut branched DNA intermediates that originate directly from blocked replication forks, targeting them for origin-independent replication restart. In eukaryotes, multiple structure-specific nucleases, including Mus81-Mms4/MUS81-EME1, Yen1/GEN1, and Slx1-Slx4/SLX1-SLX4 (FANCP) have been implicated in the resolution of branched DNA intermediates. It is becoming increasingly clear that, as a group, they reflect the dual function of RuvC in cleaving recombination intermediates and failing replication forks to assist the DNA replication process

BlogForever D2.6: Data Extraction Methodology

This report outlines an inquiry into the area of web data extraction, conducted within the context of blog preservation. The report reviews theoretical advances and practical developments for implementing data extraction. The inquiry is extended through an experiment that demonstrates the effectiveness and feasibility of implementing some of the suggested approaches. More specifically, the report discusses an approach based on unsupervised machine learning that employs the RSS feeds and HTML representations of blogs. It outlines the possibilities of extracting semantics available in blogs and demonstrates the benefits of exploiting available standards such as microformats and microdata. The report proceeds to propose a methodology for extracting and processing blog data to further inform the design and development of the BlogForever platform

Debugging Woven Code

The ability to debug woven programs is critical to the adoption of Aspect Oriented Programming (AOP). Nevertheless, many AOP systems lack adequate support for debugging, making it difficult to diagnose faults and understand the program's structure and control flow. We discuss why debugging aspect behavior is hard and how harvesting results from related research on debugging optimized code can make the problem more tractable. We also specify general debugging criteria that we feel all AOP systems should support. We present a novel solution to the problem of debugging aspect-enabled programs. Our Wicca system is the first dynamic AOP system to support full source-level debugging of woven code. It introduces a new weaving strategy that combines source weaving with online byte-code patching. Changes to the aspect rules, or base or aspect source code are rewoven and recompiled on-the-fly. We present the results of an experiment that show how these features provide the programmer with a powerful interactive debugging experience with relatively little overhead

Promoting Healthy Families and Communities for Boys and Young Men of Color

This report talks about boys and young men of color who are at risk for poor health and developmental outcomes beginning at birth and persisting through childhood, adolescence, and young adulthood. As a result of household poverty and residence in segregated neighborhoods of concentrated disadvantage, they are disproportionately bombarded by environmental threats -- often without the benefits of supportive systems of prevention, protection, and care. This exposure to chronic stress undermines cognitive, social-emotional, and regulatory human development as well as the immune system. The parents of boys and young men of color are similarly affected, which affects boys directly in utero and interferes with their parents' abilities to promote their health and development and to protect them from harm as they mature

Counteracting Bloom Filter Encoding Techniques for Private Record Linkage

Record Linkage is a process of combining records representing same entity spread across multiple and different data sources, primarily for data analytics. Traditionally, this could be performed with comparing personal identifiers present in data (e.g., given name, surname, social security number etc.). However, sharing information across databases maintained by disparate organizations leads to exchange of personal information pertaining to an individual. In practice, various statutory regulations and policies prohibit the disclosure of such identifiers. Private record linkage (PRL) techniques have been implemented to execute record linkage without disclosing any information about other dissimilar records. Various techniques have been proposed to implement PRL, including cryptographically secure multi-party computational protocols. However, these protocols have been debated over the scalability factors as they are computationally extensive by nature. Bloom filter encoding (BFE) for private record linkage has become a topic of recent interest in the medical informatics community due to their versatility and ability to match records approximately in a manner that is (ostensibly) privacy-preserving. It also has the advantage of computing matches directly in plaintext space making them much faster than their secure mutli-party computation counterparts. The trouble with BFEs lies in their security guarantees: by their very nature BFEs leak information to assist in the matching process. Despite this known shortcoming, BFEs continue to be studied in the context of new heuristically designed countermeasures to address known attacks. A new class of set-intersection attack is proposed in this thesis which re-examines the security of BFEs by conducting experiments, demonstrating an inverse relationship between security and accuracy. With real-world deployment of BFEs in the health information sector approaching, the results from this work will generate renewed discussion around the security of BFEs as well as motivate research into new, more efficient multi-party protocols for private approximate matching