Assessment of the Autism Spectrum Disorder Based on Machine Learning and Social Visual Attention: A Systematic Review

The assessment of autism spectrum disorder (ASD) is based on semi-structured procedures addressed to children and caregivers. Such methods rely on the evaluation of behavioural symptoms rather than on the objective evaluation of psychophysiological underpinnings. Advances in research provided evidence of modern procedures for the early assessment of ASD, involving both machine learning (ML) techniques and biomarkers, as eye movements (EM) towards social stimuli. This systematic review provides a comprehensive discussion of 11 papers regarding the early assessment of ASD based on ML techniques and children's social visual attention (SVA). Evidences suggest ML as a relevant technique for the early assessment of ASD, which might represent a valid biomarker-based procedure to objectively make diagnosis. Limitations and future directions are discussed

Automating autism: Disability, discourse, and Artificial Intelligence

As Artificial Intelligence (AI) systems shift to interact with new domains and populations, so does AI ethics: a relatively nascent subdiscipline that frequently concerns itself with questions of “fairness” and “accountability.” This fairness-centred approach has been criticized for (amongst other things) lacking the ability to address discursive, rather than distributional, injustices. In this paper I simultaneously validate these concerns, and work to correct the relative silence of both conventional and critical AI ethicists around disability, by exploring the narratives deployed by AI researchers in discussing and designing systems around autism. Demonstrating that these narratives frequently perpetuate a dangerously dehumanizing model of autistic people, I explore the material consequences this might have. More importantly, I highlight the ways in which discursive harms—particularly discursive harms around dehumanization—are not simply inadequately handled by conventional AI ethics approaches, but actively invisible to them. I urge AI ethicists to critically and immediately begin grappling with the likely consequences of an approach to ethics which focuses on personhood and agency, in a world in which many populations are treated as having neither. I suggest that this issue requires a substantial revisiting of the underlying premises of AI ethics, and point to some possible directions in which researchers and practitioners might look for inspiration

Low-Cost Sensors and Biological Signals

Many sensors are currently available at prices lower than USD 100 and cover a wide range of biological signals: motion, muscle activity, heart rate, etc. Such low-cost sensors have metrological features allowing them to be used in everyday life and clinical applications, where gold-standard material is both too expensive and time-consuming to be used. The selected papers present current applications of low-cost sensors in domains such as physiotherapy, rehabilitation, and affective technologies. The results cover various aspects of low-cost sensor technology from hardware design to software optimization

Non Invasive Tools for Early Detection of Autism Spectrum Disorders

Autism Spectrum Disorders (ASDs) describe a set of neurodevelopmental disorders. ASD represents a significant public health problem. Currently, ASDs are not diagnosed before the 2nd year of life but an early identification of ASDs would be crucial as interventions are much more effective than specific therapies starting in later childhood. To this aim, cheap an contact-less automatic approaches recently aroused great clinical interest. Among them, the cry and the movements of the newborn, both involving the central nervous system, are proposed as possible indicators of neurological disorders. This PhD work is a first step towards solving this challenging problem. An integrated system is presented enabling the recording of audio (crying) and video (movements) data of the newborn, their automatic analysis with innovative techniques for the extraction of clinically relevant parameters and their classification with data mining techniques. New robust algorithms were developed for the selection of the voiced parts of the cry signal, the estimation of acoustic parameters based on the wavelet transform and the analysis of the infant’s general movements (GMs) through a new body model for segmentation and 2D reconstruction. In addition to a thorough literature review this thesis presents the state of the art on these topics that shows that no studies exist concerning normative ranges for newborn infant cry in the first 6 months of life nor the correlation between cry and movements. Through the new automatic methods a population of control infants (“low-risk”, LR) was compared to a group of “high-risk” (HR) infants, i.e. siblings of children already diagnosed with ASD. A subset of LR infants clinically diagnosed as newborns with Typical Development (TD) and one affected by ASD were compared. The results show that the selected acoustic parameters allow good differentiation between the two groups. This result provides new perspectives both diagnostic and therapeutic

Children’s Fitness and Quality of Movement

Introduction: Movement is essential to life and plays a key role in development throughout childhood. Movement can be assessed by its quantity and quality. Movement is important to measure as it can aid early intervention. Current research suggests that global levels of fitness are declining, with a lack of research surrounding children’s natural fitness levels as they get older. Quantity of movement is commonly studied, however quality is becoming increasingly popular. A clear understanding of the methods of technology used to measure quality of movement is important as understanding this area will aid in designing appropriate interventions.Methods: This thesis comprises of two experimental studies. Study one is a repeated measures design using previously collected Swanlinx data to investigate how components of children’s fitness change over a one-year period. Study two is a scoping review investigating the measurement of quality of movement with technology in the form of MEM’s devices, while aiming to gain clarity on the definition of quality.Results: Study one revealed that children’s fitness levels increase across a one-year period, in all components of fitness, except sit and reach. Boys performed significantly better in all fitness components, apart from sit and reach. Study two demonstrated the broad field that is included under the term of quality, showing clarity is needed in this area. A large number of devices, movements and populations are being observed, with multiple definitions of quality which is dependent on the metrics collected.Conclusion: Study one concludes that children’s fitness levels increase over one-year, with boys performing better than girls. This can be used to understand children’s natural fitness levels and aid future interventions in participation. Study two concludes that there are multiple ways to assess quality of movement however a clear definition of the quality should be stated, aiding comparison of quality

Motor control adherence to the two-thirds power law differs in autistic development

Purpose: Autistic individuals often exhibit motor atypicalities, which may relate to difficulties in social communication. This study utilized a smart tablet activity to computationally characterize motor control by testing adherence to the two-thirds power law (2/3 PL), which captures a systematic covariation between velocity and curvature in motor execution and governs many forms of human movement. Methods: Children aged 4-8 years old participated in this study, including 24 autistic children and 33 typically developing children. Participants drew and traced ellipses on an iPad. We extracted data from finger movements on the screen, and computed adherence to the 2/3 PL and other kinematic metrics. Measures of cognitive and motor functioning were also collected. Results: In comparison to the typically developing group, the autistic group demonstrated greater velocity modulation between curved and straight sections of movement, increased levels of acceleration and jerk, and greater intra- and inter-individual variability across several kinematic variables. Further, significant motor control development was observed in typically developing children, but not in those with autism. Conclusion: This study is the first to examine motor control adherence to the 2/3 PL in autistic children, revealing overall diminished motor control. Less smooth, more varied movement and an indication of developmental stasis in autistic children were observed. This study offers a novel tool for computational characterization of the autism motor signature in children’s development, demonstrating how smart tablet technology enables accessible assessment of children’s motor performance in an objective, quantifiable and scalable manner

Hands-Off Therapist Robot Behavior Adaptation to User Personality for Post-Stroke Rehabilitation Therapy

This paper describes a hands-off therapist robot that monitors, assists, encourages, and socially interacts with post-stroke users in the process of rehabilitation exercises. We developed a behavior adaptation system that takes advantage of the users introversion-extroversion personality trait and the number of exercises performed in order to adjust its social interaction parameters (e.g., interaction distances/proxemics, speed, and vocal content) toward a customized post-stroke rehabilitation therapy. The experimental results demonstrate the robot's autonomous behavior adaptation to the user's personality and the resulting user improvements of the exercise task performance

Sensor-Based Locomotion Data Mining for Supporting the Diagnosis of Neurodegenerative Disorders: A Survey

Locomotion characteristics and movement patterns are reliable indicators of neurodegenerative diseases (NDDs). This survey provides a systematic literature review of locomotion data mining systems for supporting NDD diagnosis. We discuss techniques for discovering low-level locomotion indicators, sensor data acquisition and processing methods, and NDD detection algorithms. The survey presents a comprehensive discussion on the main challenges for this active area, including the addressed diseases, locomotion data types, duration of monitoring, employed algorithms, and experimental validation strategies. We also identify prominent open challenges and research directions regarding ethics and privacy issues, technological and usability aspects, and availability of public benchmarks

Decoding Neural Signals with Computational Models: A Systematic Review of Invasive BMI

There are significant milestones in modern human's civilization in which mankind stepped into a different level of life with a new spectrum of possibilities and comfort. From fire-lighting technology and wheeled wagons to writing, electricity and the Internet, each one changed our lives dramatically. In this paper, we take a deep look into the invasive Brain Machine Interface (BMI), an ambitious and cutting-edge technology which has the potential to be another important milestone in human civilization. Not only beneficial for patients with severe medical conditions, the invasive BMI technology can significantly impact different technologies and almost every aspect of human's life. We review the biological and engineering concepts that underpin the implementation of BMI applications. There are various essential techniques that are necessary for making invasive BMI applications a reality. We review these through providing an analysis of (i) possible applications of invasive BMI technology, (ii) the methods and devices for detecting and decoding brain signals, as well as (iii) possible options for stimulating signals into human's brain. Finally, we discuss the challenges and opportunities of invasive BMI for further development in the area.Comment: 51 pages, 14 figures, review articl