251 research outputs found

    Learning and digital inclusion: the ELAMP project

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    The Electronic Learning and Mobility Project (ELAMP) was a nationally funded project by the Department for Children, Schools and Families, which ran from 2004 to 2010. The main aim of ELAMP was to improve the education of Traveller children, particularly highly mobile learners. ELAMP focussed upon the use of mobile technology and distance learning to support, enhance and extend young Travellers’ educational and vocational opportunities. This article will reflect upon the learning and technological experiences and opportunities that the ELAMP project provided for Traveller children, young people and their families. In doing so it will critically consider the value of information technology in working with Traveller communities and advancing their educational opportunities. Reviewing ELAMP work will also demonstrate how the use of mobile technology can improve educational outcomes and Traveller families’ digital inclusion. Now that the project has ended, this article will question why we are not using what we learnt from ELAMP to move forward

    Observational Derivation of Einstein's``Law of the Constancy of the Velocity of Light in Vacuo"

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    On the basis of Galilean invariance and the Doppler formula, combined with an observational condition, it is shown that the constancy of the velocity of light {\it in vacuo} can be derived, together with time-dilatation and Lorentz contraction. It is not necessary to take the constancy as a postulate.Comment: 5 pages AIP-tex. Conference "Quantum Theory: Reconsideration of Foundations 3", Vaxjo Sweden, June 2005. To appear in AIP conference serie

    Electric LAMP: Virtual Loop-Mediated Isothermal AMPlification

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    We present eLAMP, a PERL script, with Tk graphical interface, that electronically simulates Loop-mediated AMPlification (LAMP) allowing users to efficiently test putative LAMP primers on a set of target sequences. eLAMP can match primers to templates using either exact (via builtin PERL regular expressions) or approximate matching (via the tre-agrep library). Performance was tested on 40 whole genome sequences of Staphylococcus. eLAMP correctly predicted that the two tested primer sets would amplify from S. aureus genomes and not amplify from other Staphylococcus species. Open source (GNU Public License) PERL scripts are available for download from the New York Botanical Garden’s website

    Rapid detection of mobilized colistin resistance using a nucleic acid based lab-on-a-chip diagnostic system

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    The increasing prevalence of antimicrobial resistance is a serious threat to global public health. One of the most concerning trends is the rapid spread of Carbapenemase-Producing Organisms (CPO), where colistin has become the last-resort antibiotic treatment. The emergence of colistin resistance, including the spread of mobilized colistin resistance (mcr) genes, raises the possibility of untreatable bacterial infections and motivates the development of improved diagnostics for the detection of colistin-resistant organisms. This work demonstrates a rapid response for detecting the most recently reported mcr gene, mcr−9, using a portable and affordable lab-on-a-chip (LoC) platform, offering a promising alternative to conventional laboratory-based instruments such as real-time PCR (qPCR). The platform combines semiconductor technology, for non-optical real-time DNA sensing, with a smartphone application for data acquisition, visualization and cloud connectivity. This technology is enabled by using loop-mediated isothermal amplification (LAMP) as the chemistry for targeted DNA detection, by virtue of its high sensitivity, specificity, yield, and manageable temperature requirements. Here, we have developed the first LAMP assay for mcr−9 - showing high sensitivity (down to 100 genomic copies/reaction) and high specificity (no cross-reactivity with other mcr variants). This assay is demonstrated through supporting a hospital investigation where we analyzed nucleic acids extracted from 128 carbapenemase-producing bacteria isolated from clinical and screening samples and found that 41 carried mcr−9 (validated using whole genome sequencing). Average positive detection times were 6.58 ± 0.42 min when performing the experiments on a conventional qPCR instrument (n = 41). For validating the translation of the LAMP assay onto a LoC platform, a subset of the samples were tested (n = 20), showing average detection times of 6.83 ± 0.92 min for positive isolates (n = 14). All experiments detected mcr−9 in under 10 min, and both platforms showed no statistically significant difference (p-value > 0.05). When sample preparation and throughput capabilities are integrated within this LoC platform, the adoption of this technology for the rapid detection and surveillance of antimicrobial resistance genes will decrease the turnaround time for DNA detection and resistotyping, improving diagnostic capabilities, patient outcomes, and the management of infectious diseases

    Light bending scenario for accreting black holes in X-ray polarimetry

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    We discuss a model of an X-ray illuminating source above an accretion disk of a rotating black hole. Within the so called lamp-post scheme we compute the expected (observed) polarization properties of the radiation reaching an observer. We explore the dependencies on model parameters, employing Monte Carlo radiation transfer computations of the X-ray reflection on the accretion disk and taking general relativity effects into account. In particular, we discuss the role of the black hole spin, of the observer viewing angle, and of the primary X-ray source distance from the black hole. We give several examples of the resulting polarization degree for two types of exemplary objects - active galactic nuclei and Galactic black holes. In order to assess potential observability of the polarization features, we assume the sensitivity of the proposed New Hard X-ray Mission (NHXM). We examine the energy range from several keV to ~50 keV, so the iron-line complex and the Compton hump are included in our model spectra. We find the resultant polarization degree to increase at the higher end of the studied energy band, i.e. at >~20 keV. Thus, the best results for polarimetry of reflection spectra should be achieved at the Compton hump energy region. We also obtain higher polarization degree for large spin values of the black hole, small heights of the primary source, and low inclination angles of the observer.Comment: 17 pages, 14 figures, accepted in Ap

    The electrical performance of modern compact fluorescent lamps

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    Compact Fluorescent Lamps (CFL) are highly non-linear devices which are likely to experience very high growth in penetration levels, especially in domestic environments, in Australia over the next 2 – 3 years. This will occur due to the decision taken by the Australian Federal Government to ban the sale of incandescent light globes after 2009 as measures towards meeting the needs for demand side management and climate change abatement. While CFL technology has been in existence since the late 1980s penetration levels are now increasing to a point where the total CFL load cannot be considered negligible compared to other non-linear domestic loads. This paper seeks to redress the lack of concise data available describing the performance of modern CFLs over a range of influence factors such as input voltage magnitude and harmonic distortion. It seeks to provide definitive characterisation of the modern CFL in terms of harmonic and power factor performance over a range of input supply conditions. This aim is achieved through laboratory testing of 25 CFLs of different brands, construction types and rated power levels

    Developing and sustaining shared leadership in higher education

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    In recent years, concepts of shared and distributed leadership that view leadership ‘as a group quality, as a set of functions which must be carried out by the group’3 have emerged as popular alternatives to heroic and individual approaches. A shared leadership perspective shifts the focus on leadership from person and position to process and is now widely advocated across public, private and not-for-profit settings where there is a need to influence and collaborate across organisational and professional boundaries.Within higher education, shared leadership offers a compelling alternative to the discourse of managerialism (based on principles of new public management), which has become increasingly prevalent within the sector. In a context where many are sceptical of traditional influence and authority, it has been suggested that shared leadership may offer a means of reconnecting academics with a sense of collegiality, citizenship and community.Drawing on the authors’ extensive experience of researching and developing shared leadership in British and Australian universities, this stimulus paper explores what individuals and institutions can do to help develop and sustain more inclusive and shared leadership cultures and practices. It is targeted mainly at middle- to senior-level academic and professional service managers, and leadership and organisational development specialists, and seeks to provide practical as well as conceptual guidance for day-to-day leadership practice and development.A wide range of sources has been used in compiling this paper, going beyond abstract concepts to present resources and examples of using a shared leadership approach to achieve change at many levels and across many institutions that make up the higher education sector in the UK and Australia. A key aim of this paper is to bridge the gap between shared leadership theory, practice and development.The paper is structured into three main parts – context, practice and engagement – that consider, in turn, the conceptual framing, institutional practice and individual and cultural change aspects of shared leadership. Alongside a review of relevant theory and research, these sections present a series of resources, cases and examples to help assess current leadership practice and identify future action for shared leadership.The tools, practices and insights in this report will help debunk common myths and misconceptions about shared leadership and offer a systemic framework for developing and sustaining a shared leadership approach in higher education. Practical examples from Australia and the UK are included throughout, and each section contains reflective questions to assist in learning and application.Overall this paper suggests that shared leadership offers a viable and effective approach for developing and enhancing leadership in higher education and for engaging a wide range of interests and expertise in the leadership process. It is not, however, a panacea and we encourage the reader to take an open yet critical approach in which consideration is given to the wider social, political and cultural context in which leadership takes place
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