237,052 research outputs found

    The Whalesong

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    A cool way to spend summer -- Skater's Edge -- Editorial & opinion -- Arnold vs. Atkins -- The biting truth -- Governor's wolf policy out of step -- Alaska winter -- Informed traitor advise -- What will happen to Sammy? -- UAS February events -- Update: New lodge dog -- Campus poll -- UAS says goodbye to Amanda Knerr -- Big Fish: Worthwhile or worthless -- In celebration of Black History Month -- While the sheep is away the monkey can pla

    An integrated 4249 marker FISH/RH map of the canine genome

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    BACKGROUND: The 156 breeds of dog recognized by the American Kennel Club offer a unique opportunity to map genes important in genetic variation. Each breed features a defining constellation of morphological and behavioral traits, often generated by deliberate crossing of closely related individuals, leading to a high rate of genetic disease in many breeds. Understanding the genetic basis of both phenotypic variation and disease susceptibility in the dog provides new ways in which to dissect the genetics of human health and biology. RESULTS: To facilitate both genetic mapping and cloning efforts, we have constructed an integrated canine genome map that is both dense and accurate. The resulting resource encompasses 4249 markers, and was constructed using the RHDF5000-2 whole genome radiation hybrid panel. The radiation hybrid (RH) map features a density of one marker every 900 Kb and contains 1760 bacterial artificial chromosome clones (BACs) localized to 1423 unique positions, 851 of which have also been mapped by fluorescence in situ hybridization (FISH). The two data sets show excellent concordance. Excluding the Y chromosome, the map features an RH/FISH mapped BAC every 3.5 Mb and an RH mapped BAC-end, on average, every 2 Mb. For 2233 markers, the orthologous human genes have been established, allowing the identification of 79 conserved segments (CS) between the dog and human genomes, dramatically extending the length of most previously described CS. CONCLUSIONS: These results provide a necessary resource for the canine genome mapping community to undertake positional cloning experiments and provide new insights into the comparative canine-human genome maps

    Dog, Fish, Shoes (Or Beans)

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    A natural cure for the pet fish problem: feature emergence as classificatory composition

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    Where do emergent features come from? This has long been an intriging puzzle. The concept of pet fish illustrates the difficulty. Most people expect pet fish to live in bowls, even though this is not something either pets or fish normally do. The inference that pet fish have the feature of living in bowls cannot be explained purely in terms of the constituents themselves. The feature seems to emerge. The present paper aims to explain this effect using notions of classificatory composition. Adjoined concept references are taken to construct classifications rather than combinations; a pet fish is taken to be a fish classified as a pet rather than a combination of a pet a fish. It is also shown that, where concepts have a compositional representation, feature emergence can be accounted for in terms of compositional accommodation

    Evidence of Songbird Intoxication From Rozol Application at a Black-Tailed Prairie Dog Colony

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    Concerns about avian poisonings from anticoagulant rodenticides have traditionally focused on secondary poisoning of raptors exposed by feeding on contaminated mammalian prey. However, ground foraging songbirds can be directly poisoned from operational applications of the anticoagulant rodenticide RozolH (0.005% chlorophacinone, active ingredient) applied as a grain bait, at black-tailed prairie dog Cynomys ludovicianus colonies. A dead western meadowlark Sturnella neglecta recovered from the study prairie dog colony displayed hemorrhaging in brain and pectoral muscle tissue, and it contained chlorophacinone residue concentrations of 0.59 and 0.49 mg/g (wet weight) in the liver and intestinal contents, respectively. Chlorophacinone residues from two Rozol-colored songbird droppings found at the study colony were 0.09 and 0.46 mg/g (wet weight). The timing of the meadowlark mortality and the occurrence of discolored droppings show that songbird exposure and poisoning can occur weeks after a Rozol application

    ISER 2012 Working Paper No. 1

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    Large resource development projects take years to plan. During that planning time, the public frequently debates the potential benefits and risks of a project, but with incomplete information. In these debates, some people might assert that a project would have great benefits, while others might assert that it would certainly harm the environment. At the same time, the developer will be assessing different designs, before finally submitting one to the government permitting agencies for evaluation and public scrutiny. For large mines in Alaska, the government permitting process takes years, and often includes an ecological risk assessment. This assessment is a data-intensive, scientific evaluation of the project’s potential ecological risks, based on the specific details of the project. Recently, some organizations have tried to bring scientific rigor to the pre-design public discussions, especially for mining projects, through a pre-design risk ecological risk assessment. This is a scientific assessment of the environmental risks a project might pose, before the details of project design, risk-prevention, and risk-mitigation measures are known. It is important to know whether pre-design risk assessment is a viable method for drawing conclusions about risks of projects. If valid risk predictions can be made at that stage, then people or governments would not have to wait for either a design or for the detailed evaluation that is done during the permitting process. Such an approach could be used to short cut permitting. It could affect project financing; it could affect the schedule, priority, or even the resources that governments put toward evaluating a project. But perhaps most important: in an age where public perceptions are an important influence on a project’s viability and government permitting decisions, a realistic risk assessment can be used to focus public attention on the facts. But if the methodology is flawed and results in poor quality information and unsupportable conclusions, then a pre-design risk assessment could unjustifiably either inflame or calm the public, depending on what it predicts.Executive Summary / Section 1. Introduction / Section 2. Overview of Ecological Risk / Section 3. Ecological Risk Assessment Methodology / Section 4. Examples of Post-Design Ecological Risk Assessments / Section 5. Pre-Design Ecological Risk Assessment: Risks of Large Scale Mining in the Bristol Bay Watershed / Section 6. Conclusion / Bibliograph

    Is the Mesolithic-Neolithic Subsistence Dichotomy Real? New Stable Isotope Evidence from the Danube Gorges

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    The article presents new results of stable isotope analyses made on animal and human bones from the Mesolithic-early Neolithic sites of Lepenski Vir and Vlasac in the Danube Gorges of the Balkans. It reconstructs the food web for the region during these periods on the basis of stable isotope analyses of mammal and fish species found at Vlasac. These results are compared to measurements made on human burials from the two sites. In the light of these new results, the article also discusses interpretations provided by previous isotopic studies of this material. It concludes that great care is required in the interpretation of stable isotope results due to inherent methodological complexities of this type of analysis, and suggests that it is also necessary to integrate stable isotope results with information based on the examination of faunal remains and the archaeological context of analysed burials when making inferences about palaeodietary patterns
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