4,077 research outputs found
Nucleic acid probes in diagnostic medicine
The need for improved diagnostic procedures is outlined and variations in probe technology are briefly reviewed. A discussion of the application of probe technology to the diagnosis of disease in animals and humans is presented. A comparison of probe versus nonprobe diagnostics and isotopic versus nonisotopic probes is made and the current state of sequence amplification is described. The current market status of nucleic acid probes is reviewed with respect to their diagnostic application in human and veterinary medicine. Representative product examples are described and information on probes being developed that offer promise as future products is discussed
Salivary biomarkers in psychobiological medicine.
The value of salivary biomarkers for diagnostic and prognostic assessments has become increasingly well established in medicine, pharmacology, and dentistry. Certain salivary components mirror the neuro-endocrine status of the organism. Other saliva products are protein in nature, and can serve to reflect immune surveillance processes. The autonomic nervous system regulates the process of salivation, and the concentration of yet other salivary components, such as alpha-amylase, which provide a reliable outcome measure of the sympathetic response. Here, we discuss molecular technologies that have permitted giant steps in the utilization of salivary samples and micro-fluidics for the benefit of diagnostic medicine and dentistry, and their putative role in springing forward research in psychobiology
A Review on the Applications of Crowdsourcing in Human Pathology
The advent of the digital pathology has introduced new avenues of diagnostic
medicine. Among them, crowdsourcing has attracted researchers' attention in the
recent years, allowing them to engage thousands of untrained individuals in
research and diagnosis. While there exist several articles in this regard,
prior works have not collectively documented them. We, therefore, aim to review
the applications of crowdsourcing in human pathology in a semi-systematic
manner. We firstly, introduce a novel method to do a systematic search of the
literature. Utilizing this method, we, then, collect hundreds of articles and
screen them against a pre-defined set of criteria. Furthermore, we crowdsource
part of the screening process, to examine another potential application of
crowdsourcing. Finally, we review the selected articles and characterize the
prior uses of crowdsourcing in pathology
PUBH 7890 - Individual Study: Statistical Methods in Diagnostic Medicine
This course introduces the statistical concepts and methods for designing and analyzing biomarker data for diagnostic tests
Variations in pre-analytical FFPE sample processing and bioinformatics: challenges for next generation molecular diagnostic testing in clinical pathology
Advances in cellular pathology techniques will improve diagnostic medicine. However, such improvements have to overcome many challenges including variations in pre-analytical sample processing, bioinformatics data analysis and clinical interpretation of data. In order to resolve such challenges, bioinformatics needs to become more tightly coupled to the experimental methodology development
Time Management in Diagnostic Medicine
The supply chain management, by allowing the reduction of costs in logistics operations constitutes a strategic organizational asset. This paper focuses on time management in a Diagnostic Medicine facility. It aims to determine the level of time compression for 5 diagnostic examinations. Bearing this in mind, we collect the length time of each task concerning each examination and elaborate the descriptive statistics in STATA 13.0; while the process of optimization is implemented using the DMAIC approach. Our results show that total waiting time for all 5 examinations per week is 4 hours and 16 minutes and that, implementing some recommendations, the facility could perform 35 more examinations per week. This is of importance, not only in the context of cost reduction, but also to increase efficiency and improve the quality of service. Ultimately, the implementation of our recommendations will increase patients’ satisfaction
- …