2,793 research outputs found
The pros and cons of using SDL for creation of distributed services
In a competitive market for the creation of complex distributed services, time to market, development cost, maintenance and flexibility are key issues. Optimizing the development process is very much a matter of optimizing the technologies used during service creation. This paper reports on the experience gained in the Service Creation projects SCREEN and TOSCA on use of the language SDL for efficient service creation
Temporal interactions facilitate endemicity in the susceptible-infected-susceptible epidemic model
Data of physical contacts and face-to-face communications suggest temporally
varying networks as the media on which infections take place among humans and
animals. Epidemic processes on temporal networks are complicated by complexity
of both network structure and temporal dimensions. Theoretical approaches are
much needed for identifying key factors that affect dynamics of epidemics. In
particular, what factors make some temporal networks stronger media of
infection than other temporal networks is under debate. We develop a theory to
understand the susceptible-infected-susceptible epidemic model on arbitrary
temporal networks, where each contact is used for a finite duration. We show
that temporality of networks lessens the epidemic threshold such that
infections persist more easily in temporal networks than in their static
counterparts. We further show that the Lie commutator bracket of the adjacency
matrices at different times is a key determinant of the epidemic threshold in
temporal networks. The effect of temporality on the epidemic threshold, which
depends on a data set, is approximately predicted by the magnitude of a
commutator norm.Comment: 8 figures, 1 tabl
Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry
Dynamic combinatorial chemistry (DCC) is a subset of combinatorial chemistry where the library members interconvert continuously by exchanging building blocks with each other. Dynamic combinatorial libraries (DCLs) are powerful tools for discovering the unexpected and have given rise to many fascinating molecules, ranging from interlocked structures to self-replicators. Furthermore, dynamic combinatorial molecular networks can produce emergent properties at systems level, which provide exciting new opportunities in systems chemistry. In this perspective we will highlight some new methodologies in this field and analyze selected examples of DCLs that are under thermodynamic control, leading to synthetic receptors, catalytic systems, and complex self-assembled supramolecular architectures. Also reviewed are extensions of the principles of DCC to systems that are not at equilibrium and may therefore harbor richer functional behavior. Examples include self-replication and molecular machines.
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