62,242 research outputs found
DFDL: Discriminative Feature-oriented Dictionary Learning for Histopathological Image Classification
In histopathological image analysis, feature extraction for classification is
a challenging task due to the diversity of histology features suitable for each
problem as well as presence of rich geometrical structure. In this paper, we
propose an automatic feature discovery framework for extracting discriminative
class-specific features and present a low-complexity method for classification
and disease grading in histopathology. Essentially, our Discriminative
Feature-oriented Dictionary Learning (DFDL) method learns class-specific
features which are suitable for representing samples from the same class while
are poorly capable of representing samples from other classes. Experiments on
three challenging real-world image databases: 1) histopathological images of
intraductal breast lesions, 2) mammalian lung images provided by the Animal
Diagnostics Lab (ADL) at Pennsylvania State University, and 3) brain tumor
images from The Cancer Genome Atlas (TCGA) database, show the significance of
DFDL model in a variety problems over state-of-the-art methodsComment: Accepted to IEEE International Symposium on Biomedical Imaging
(ISBI), 201
Deep Learning in Cardiology
The medical field is creating large amount of data that physicians are unable
to decipher and use efficiently. Moreover, rule-based expert systems are
inefficient in solving complicated medical tasks or for creating insights using
big data. Deep learning has emerged as a more accurate and effective technology
in a wide range of medical problems such as diagnosis, prediction and
intervention. Deep learning is a representation learning method that consists
of layers that transform the data non-linearly, thus, revealing hierarchical
relationships and structures. In this review we survey deep learning
application papers that use structured data, signal and imaging modalities from
cardiology. We discuss the advantages and limitations of applying deep learning
in cardiology that also apply in medicine in general, while proposing certain
directions as the most viable for clinical use.Comment: 27 pages, 2 figures, 10 table
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Sensor, Signal, and Imaging Informatics in 2017.
ObjectiveâTo summarize significant contributions to sensor, signal, and imaging informatics literature published in 2017.MethodsâPubMedÂź and Web of ScienceÂź were searched to identify the scientific publications published in 2017 that addressed sensors, signals, and imaging in medical informatics. Fifteen papers were selected by consensus as candidate best papers. Each candidate article was reviewed by section editors and at least two other external reviewers. The final selection of the four best papers was conducted by the editorial board of the International Medical Informatics Association (IMIA) Yearbook.ResultsâThe selected papers of 2017 demonstrate the important scientific advances in management and analysis of sensor, signal, and imaging information.ConclusionThe growth of signal and imaging data and the increasing power of machine learning techniques have engendered new opportunities for research in medical informatics. This synopsis highlights cutting-edge contributions to the science of Sensor, Signal, and Imaging Informatics
On the Use of XML in Medical Imaging Web-Based Applications
The rapid growth of digital technology in medical fields over recent years has increased the need for applications able to manage patient medical records, imaging data, and chart information. Web-based applications are implemented with the purpose to link digital databases, storage and transmission protocols, management of large volumes of data and security concepts, allowing the possibility to read, analyze, and even diagnose remotely from the medical center where the information was acquired. The objective of this paper is to analyze the use of the Extensible Markup Language (XML) language in web-based applications that aid in diagnosis or treatment of patients, considering how this protocol allows indexing and exchanging the huge amount of information associated with each medical case. The purpose of this paper is to point out the main advantages and drawbacks of the XML technology in order to provide key ideas for future web-based applicationsPeer ReviewedPostprint (author's final draft
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Challenges of ultra large scale integration of biomedical computing systems
The NCRI Informatics Initiative is overseeing the implementation of an informatics
framework for the UK cancer research community. The framework advocates an integrated
multidisciplinary method of working between scientific and medical communities. Key to this
process is community adoption of high quality acquisition, storage, sharing and integration of
diverse data elements to improve knowledge of the causes, prevention and treatment of
cancer. The integration of the complex data and meta-data used by these multiple
communities is a significant challenge and there are technical, resource-based and
sociological issues to be addressed. In this paper we review progress aimed at establishing
the framework and outline key challenges in ultra large scale integration of biomedical
computing systems
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