99,503 research outputs found
Annotation and Curation of the Protein Data Bank
The Protein Data Bank (PDB) is the worldwide repository for experimentally determined 3D structures of biological macromolecules. Established in 1971 with just seven structures, it presently includes more than 56,000 entries. To maintain the highest standards in curation and processing, the members of the worldwide Protein Data Bank (wwPDB) collaborate in data annotation and the development of procedures, tools, and resources. Annotation-related issues, particularly those impacted by new developments
in structural biology, are critically reviewed at in-person and virtual meetings regularly and frequently. Comprehensive documentation of the procedures, formats, and related data dictionaries used in data annotation are available at the wwPDB website(www.wwpdb.org).

Mindful of the impact that changes in annotation procedures or data format may have on users, changes are carefully managed and communicated in a timely fashion. In cases involving complex scientific or policy issues, input is sought from advisory committees, standing task forces, experimental method developers, and community experts. This is exemplified by creation of the recently-released version of the PDB archive which updates and further standardizes database references, small molecule chemistry, biological assemblies, and active sites
Definition of Tire Properties Required for Landing System Analysis
The data bank constructed provided two basic advantages for the user of aircraft tire information. First, computerization of the data bank allowed mechanical property data to be stored, corrected, updated, and revised quickly and easily as more reliable tests and measurements were carried out. Secondly, the format of the book which can be printed from the computerized data bank can be easily adjusted to suit the needs of the users without the great expense normally associated with reprinting and editing books set by ordinary typography
PDBTM: Protein Data Bank of transmembrane proteins after 8 years
The PDBTM database (available at http://pdbtm
.enzim.hu), the first comprehensive and up-to-date
transmembrane protein selection of the Protein
Data Bank, was launched in 2004. The database
was created and has been continuously updated
by the TMDET algorithm that is able to distinguish
between transmembrane and non-transmembrane
proteins using their 3D atomic coordinates only.
The TMDET algorithm can locate the spatial positions
of transmembrane proteins in lipid bilayer as
well. During the last 8 years not only the size of the
PDBTM database has been steadily growing from
~400 to 1700 entries but also new structural
elements have been identified, in addition to the
well-known a-helical bundle and b-barrel structures.
Numerous ‘exotic’ transmembrane protein structures
have been solved since the first release,
which has made it necessary to define these new
structural elements, such as membrane loops or
interfacial helices in the database. This article
reports the new features of the PDBTM database
that have been added since its first release, and
our current efforts to keep the database
up-to-date and easy to use so that it may continue
to serve as a fundamental resource for the scientific
community
Duke Data Bank
NASA computerized image processing techniques are an integral part of a cardiovascular data bank at Duke University Medical Center. Developed by Dr. C. F. Starmer and colleagues at Duke, the data bank documents the Center's clinical experience with more than 4,000 heart patients as an aid to diagnosis and treatment of heart disease. Data is stored in a computerized system that allows a physician to summon detailed records of former patients whose medical profiles are similar to those of a new patient. A video display (photo) and printed report shows prognostic information for the new patient based on similar past experience
Teaching and Professional Fellowship Report 2002/3 : Fourier Transform Infra Red (FTIR) Spectroscopy
A review of existing and production of new relevant spectra to establish a live data bank for application across the University of the Arts London and wider community
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