Bachmann, P. A.

Eichhorn, Werner

English

Universität München: Elektronischen Publikationen

M 1 tfs^ 
21/1/84 
keleased January 1984 
S. Karger 
Medical and Scientific 
Publishers 
Basel • München • Paris 
London New York 
Tokyo•Sydney 
Clinical Chemotherapy 
Edited by Helmut P. Kuemmerle 
Visiting Professor for Clinical Pharmacology at the Tokyo Medical College; Visiting Professor 
for Clinical Pharmacology at the College of Mediane, Hanyang University in Seoul/Corea; 
Specialist in Obstetrics and Gynecology, Clinical Pharmacology and Chemotherapy; Presi-
dent of the International Society of Chemotherapy 
Applications for chemotherapy have witnessed incredible growth since the early 20th 
Century... this new three volume series „Clinical Chemotherapy" presents an authoritative 
Position and review of proven therapeutic concepts and recent developments in this field. 
15% reduced preferential price for subscribers to this series 
Volume I: Fundamentals 
1983. 503 pages, 181 figures, 73 tables 
cloth approx $ 96.00/DM 240,-
(Pref. price approx. $ 82.00/DM 204,-) 
Upcoming volumes in the Clinical Chemotherapy series: 
Volume II: Antimicrobial Chemotherapy 
1984. Cloth approx. $ 96.00/approx. DM 240,-
(Pref. price approx. $ 82.00/approx. DM 204,-) 
Volume III: Antineoplastic Chemotherapy 
1984. Cloth approx. $ 96.00/approx. DM 240,-
(Pref. price approx. $ 82.00/approx. DM 204,-) 
Georg Thieme Verlag Stuttgart • New York 
F 83211 
Bayen s Ohe 
Staaten - thofc 
Mär cnen 
V J 
Vol. 211, 1984 
Editor-in-Chief 
J.L. Melnick, USA 
Associ&te Editor F. Rapp, USA 
Intervirology 
The Journal of the Virology Division, 
International Union of Microbiological Societies 
Section Editors* 
Structure of Viruses 
M.V. Nermut, UK (Section Editor) 
T.F. Anderson, USA 
S. Dales, Canada 
R.W. Hörne, UK 
F. A. Murphy, USA 
E. Norrby, Sweden 
G. Ruttkay-Nedecky, Czechoslovakia 
J. Skehel, UK 
D.W. Verwoerd, S. Africa 
Plant Virology 
A. Gibbs, Australia (Section Editor) 
J.B. Bancroft, UK 
R. Bercks, FRG 
H. Fraenkel-Conrat, USA 
R.W. Fulton, USA 
B. D. Harrison, UK 
Z. Hidaka, Japan 
L. Hirth, France 
R.J. Shepherd, USA 
V. Valenta, Czechoslovakia 
Invertebrate Virology 
J.F. Longworth, New Zealand 
(Section Editor) 
K. Aizawa, Japan 
L. Bailey, UK 
D. C. Kelly, UK 
E. Kurstak, Canada 
K. Maramorosch, USA 
C. C. Payne, UK 
C. Reinganum, Australia 
D. W. Roberts, USA 
R.R. Rueckert, USA 
C. Vago, France 
J.L. Vaughn, USA 
Füll addresses of the Editorial 
Board members may be obtained 
firom the office of the Editor-in-
Chief or from the Publisher. 
Bacteriophage 
N.D. Zinder, USA (Section Editor) 
D. Botstein, USA 
D.E. Bradley, Canada 
A. Eisenstark, USA 
F. A. Eiserling, USA 
W. Fiers, Belgium 
R.M. Franklin, Switzerland 
D. M. Goldfarb, USSR 
R. Haselkorn, USA 
P.H. Hofschneider, FRG 
M. Schweiger, FRG 
E. R. Signer, USA 
Virus-Cell Relationship 
G. Klein, Sweden (Section Editor) 
R. Bablanian, USA 
F. Brown, UK 
R.W. Compans, USA 
A. Granoff, USA 
I. Grosser, France 
W.G. Laver, Australia 
L. Kjellen, Sweden 
T.C. Merigan, USA 
L. Montagnier, France 
B. Moss, USA 
W.C. Russell, UK 
R. Sheinin, Canada 
H. zur Hausen, FRG 
Replication ofAnimal Viruses 
D. W. Kingsbury, USA (Section Editor) 
V.l. Agol, USSR 
Y. Becker, Israel 
M. Bratt, USA 
E. Fanning, FRG 
M. Girard, France 
A. Graham, Canada 
A.S. Huang, USA 
W.K. Joklik, USA 
A. S. Kaplan, USA 
R.A. Lazzarini, USA 
J.V. Maizel, Jr., USA 
B. R. McAuslan, Australia 
L. Philipson, Sweden 
M.E. Reichmann, USA 
B. Roizman, USA 
R. Rott, FRG 
V. Stollar, USA 
P. Wildy, UK 
V.M. Zhdanov, USSR 
WIBIHB 
Genetics 
C R . Pringle, UK (Section Editor) 
Y. Ghendon, USSR 
H. Hanafusa, USA 
E.D. Kilbourne, USA 
S. Kit, USA 
J.F. Sambrook, USA 
J.H. Subak-Sharpe, UK 
P.K. Vogt, USA 
J. Zavada, Czechoslovakia 
Ecology/Epidemiology 
E. H. Lennette, USA (Section Editor) 
F. L. Black, USA 
D. Blaskovic, Czechoslovakia 
R.M. Chanock, USA 
F. Dekking, Netherlands 
R.W. Emmons, USA 
S. Gaidamovich, USSR 
N. Goldblum, Israel 
Huang Chen-hsiang, China 
K. Johnson, USA 
J.A.R. Miles, New Zealand 
N. Nathanson, USA 
W.E. Rawls, Canada 
L. Rosen, USA 
J. van der Veen, Netherlands 
H. von Magnus, Denmark 
H.A. Wenner, USA 
Oncology 
F. Rapp, USA (Section Editor) 
H. Bauer, FRG 
J.S. Butel, USA 
M.A. Epstein, UK 
R.C. Gallo, USA 
M. Hill, France 
Y. Ito, Japan 
A.J. Levine, USA 
J.A. Levy, USA 
P. Sheldrick, France 
P.G. Spear, USA 
J. Svoboda, Czechoslovakia 
G. Todaro, USA 
J. van der Noordaa, Netherlands 
P. Vigier, France 
Immunology 
N. Oker-Blom, Finland (Section Editor) 
A.C. Allison, UK 
F. Deinhardt, FRG 
S. Fazekas de St. Groth, Switzerland 
Huang Chen-hsiang, China 
D.T. Karzon, USA 
M.B.A. Oldstone, USA 
A.J. Rhodes, Canada 
N.J. Schmidt, USA 
V. Vonka, Czechoslovakia 
Comparative Virology 
F.A. Murphy, USA (Section Editor) 
E.G. Bade, FRG 
A.J.D. Bellen, Australia 
A.G. Bukrinskaya, USSR 
A. Gibbs, Australia 
B. D. Harrison, UK 
M.C. Horzinek, Netherlands 
W.K. Joklik, USA 
E. Kurstak, Canada 
W.G. Laver, Australia 
K. Maramorosch, USA 
C. C. Payne, UK 
R.E. Shope, USA 
P. Wildy, UK 
Taxonomy 
F. Brown, UK (Section Editor) 
P.A. Bachmann, FRG 
K.W. Buck, UK 
A. Eisenstark, USA 
R.I. Hamilton, Canada 
D. W. Kingsbury, USA 
J.F. Longworth, New Zealand 
S. Karger • Medical and Scientific Publishers • Basel • München • Paris • London • New York • Tokyo • Sydney 
Drug Dosage 
The authors and the publisher have exerted every eflbrt to 
ensure that drug selection and dosage set forth in this text 
are in accord with current recommendations and practice 
at the time of publication. However, in view of ongoing 
research, changes in government regulations, and the 
constant flow of information relating to drug therapy and 
drug reactions, the reader is urged to check the package 
insert for each drug forany change in indications and dos-
age and for added warnings and precautions. This is par-
ticularly important when the recommended agent is a 
new and/or infrequently employed drug. 
All rights reserved. 
No part of this publication may be translated into other 
languages, reproduced or utilized in any form or by any 
means, electronic or mechanical, including photocopy-
ing, recording, microcopying, or by any information stor-
age and retrieval System, without permission in writing 
from the publisher or, in the case of photocopying, direct 
payment of a specified fee to the Copyright Clearance 
Center (see 'Information for Readers and Subscribers'). 
© Copyright 1984 by 
S. Karger AG, P.O. Box, CH-4009 Basel (Switzerland) 
Printed in Switzerland by 
Graphische Betriebe Coop Schweiz, Basel 
Contents Vol. 21,1984 
No. 1 Taxonomy 
Polydnaviridae - A Proposed Family of Insect Viruses with Segmented, Double-Stranded, 
Circular DNA Genomes 
Stoltz, D.B.; Krell, P.; Summers, M.D.; Vinson, S.B 1 
Original Papers 
Ultrastructural Changes during Herpes Simplex Virus Type 2 Latency and Reactivation in 
vitro 
Hung, T.; Mummaw, J.G.; Wigdahl, B.L.; Fang, Z.Y.; Huaying, J.; Rapp, F 5 
Candidate Products of Avian Myeloblastosis Virus Oncogene Region Produced by in vitro 
Translation of Genomic RNA 
Wright, S.E.; Harmon, S.A.; Smith, D.P.; Hayes, J.K.; Robertson, P.A.; Wayne, A.W. . 17 
Variation in the Structure of Varicella-Zoster Virus DNA 
Ecker, J.R.; Kudler, L.; Hyman, R.W 25 
Characterization of the Changuinola Serogroup Viruses (Reoviridae: Orbivirus) 
Travassos da Rosa, A.P.A.; Tesh, R.B.; Pinheiro, F.P.; Travassos da Rosa, J.F.S.; 
Peralta, P.H.; Knudson, D.L 38 
Replication and Serial Passage of a Singly Enveloped Baculovirus of Orgyia leucostigma in 
Homologous Cell Lines 
Sohi, S.S.; Percy, J.; Arif, B.M.; Cunningham, J.C 50 
No. 2 Original Papers 
Preclinical Changes in Weight of Scrapie-Infected Mice as a Function of Scrapie Agent-
Mouse Strain Combination 
Carp, R.I.; Callahan, S.M.; Sersen, E.A.; Moretz, R.C 61 
Sphingolipid Metabolism during Infection of Human Fibroblasts by Herpes Simplex Virus 
Type 1 
Steinhart, W.L.; Busch, J.S.; Oettgen, J.P.; Howland, J.L 70 
Mechanism of Persistence with Canine Distemper Virus: Difference between a Laboratory 
Strain and an Isolate from a Dog with Chronic Neurological Disease 
Tobler, L.H.; Imagawa, D.T 77 
The Inability of in vitro Transforming SV40 Subgenomes to Cause Tumors in vivo 
Moyer, M.P.; Arizpe, H.; Sosa, A.; Pierson, K.; Moyer, R.C 87 
Heterogeneity in Subregions of the Terminal Repeats of Herpes Simplex Virus Type 2 DNA 
Berg, F.M. van den; Ooyen, A.J.J. van; Volkers, H.; Walboomers, J.M.M 96 
Characterization of Epstein-Barr Virus-Related Thymidine Kinase Induced in Nonproducer 
Cells by Superinfection or Chemical Treatment 
Mac Gabhann, P.; Sugawara, K.; Ito, Y 104 
A Study of Measles Virus Antigens in Acutely and Persistently Infected Cells Using Mono-
clonal Antibodies: Differences in the Accumulation of Certain Viral Proteins 
Giraudon, P.; Gerald, Ch.; Wild, T.F 110 
IV Contents 
No. 3 Original Papers 
OKIO-Transformed Cell Lines: Viral Component Generation and Tumorigenicity 
Pfeifer-Ohlsson, S 121 
Mode of Action of the Antiphytoviral Compound 2,4-Dioxohexahydro-l,3,5-triazine 
(5-Azadihydrouracil) 
Schuster, G.; Arenhövel, C 134 
Effect of Acyclovir and Phosphonoformate on Cytomegalovirus Infection in Guinea Pigs 
Lucia, H.L.; Griffith, B.P.; Hsiung, G.D 141 
Accumulation of Poliovirus Proteins in Uninfected Isolated HEp-2 Cell Nuclei in vitro 
Bossart, W.; Egger, D.; Rasser, Y.; Bienz, K 150 
Glycine Mottle Virus, a Possible Member of the Tombusvirus Group 
Behncken, G.M.; Dale, J.L 159 
Short Communications 
Characterization of a Cytoplasmic Polyhedrosis Virus Infecting Manduca sexta 
Galinski, M.S.; Kingan, T.; Rohrmann, G.F.; Martignoni, M.E.; Beaudreau, G.S 167 
Protection Conferred against Junin Virus Infection in Rats 
Blejer, J.L.; Galassi, N.V.; Saavedra, V.M.; Nejamkis, M.R 174 
Transplacental Infection in Guinea Pigs Inoculated with an Attenuated Strain of Junin 
Virus 
Boxaca, M.C.; Gömez, M.d.l.M.; Berria, M.I.; Iäcono, R.F 178 
No. 4 Original Papers 
Relationship of Encephalomyocarditis Virus to Cricket Paralysis Virus of Insects 
Tinsley, T.W.; MacCallum, F.O.; Robertson, J.S.; Brown, F 181 
Localization of Hepatitis A Virus Antigen to Specific Subcellular Fractions of Hepatitis-A-
Infected Chimpanzee Liver Cells 
Khan, N.C.; Hollinger, F.B.; Melnick, J.L 187 
Changes in Cellular DNA Sequence Adjacent to Integrated Viral Genome in Transplantable 
and Nontransplantable Guinea Pig Cells Transformed by SV40 
Iwamura, Y.; Hamada, H.; Muramatsu, M.; Kato, K 195 
Interaction of Autographa californica Nuclear Polyhedrosis Virus with Two Nonpermissive 
Cell Lines 
Gröner, A.; Granados, R.R.; Burand, J.P 203 
Recognition of Host-Membrane Antigens in the Envelope of Measles Virions 
Armstrong, M.A.; Fräser, K.B.; Shirodaria, P.V 210 
Priming of Bovine Interferons 
Lefkowitz, S.S.; Luna, V.E.R 221 
Short Communications 
Specificity of the Actinomycin-D-Sensitive Function of Some RNA Plant Viruses 
Turner, M.S.; Dawson, W . 0 224 
General Information on the Vertebrate Virus Data Bank 'DAISY': First Report 
Bachmann, P.A.; Eichhorn, W 229 
Author Index 232 
Subject Index 235 
Intervirology 21: 229-231 (1984) 
© 1984 S. Karger AG, Basel 
0300-5526/84/0214-0229S2.75/0 
General Information on the Vertebrate Virus Data Bank 
'DAISY': First Report 
Peter A. Bachmann, Werner Eichhorn 
World Health Organization Collaborating Centre for the Collection and Evaluation 
of Data on Comparative Virology, Munich, FRG 
The aims of the work at the Munich Cen-
tre are to establish, collate and maintain de-
tailed up-to-date information on viruses af-
fecting animals and man and to establish a 
data bank on viruses of vertebrates in a com-
puterized System. For this purpose, a ques-
tionnaire has been developed containing 
over 200 items, including relevant references. 
Specialists fill out questionnaires on a certain 
virus, which are then put into the data bank. 
The virus questionnaires principally consist 
of five sections: general data (taxonomy, his-
tory, availability of reagents); viral proper-
ties (nucleic acid, proteins, lipids, carbohy-
drates, physicochemical relationships); di-
agnosis (viral and serological diagnosis); 
natural and experimental infection (trans-
mission, course of infection, immunological 
response); and selected references. 
A special Computer program has been de-
veloped for the virus data bank employing 
the programming language PASCAL and a 
strictly sequential file concept. This System 
Address inquiries fo:Dr. P.A. Bachmann, Institute 
for Medical Microbiology, Infectious and Epidemie 
Diseases, Veterinary Faculty, University of Munich, 
Veterinärstrasse 13, D-8000 Munich 22 (FRG) 
Received: September 20, 1983 
allows for unlimited corrections to be made 
on each questionnaire, while other files can 
be used for retrieval. The data bank has four 
independent features: input and update of 
questionnaires; entering of questionnaires 
(updated) into the data bank set; selection of 
a virus questionnaire and its transfer to the 
input file (update); and retrieval. 
The data bank program is compatible with 
most of the commercially available Systems. 
All data are stored on magnetic dises. There 
is a wide ränge of options for the retrieval of 
data: retrieval of completed virus data ques-
tionnaires; retrieval of certain parts of the 
questionnaires; retrieval of answers to a 
single or multiple questions for all viruses in 
the data bank; and multiple linkage analysis 
for different data items (comparison of mul-
tiple data from all viruses). 
Piain language is used for all virus data 
and, to facilitate retrieval and linkage analy-
sis, a Standard list of key words has been 
compiled enabling the use of the data bank 
without complicated training. 
Regulär updating of the virus question-
naires in the data bank is planned at yearly 
intervals. Since new items (questions) will 
have to be introduced into the questionnaire, 
and others presently listed in the question-
naire deleted, Software has been developed 
230 Bachmann'Eichhorn 
to include these additional Steps in the pro-
gram. This permits changes in the present 
concept as well as in virus questionnaires 
already stored in the data bank. 
Retrieval, input and Updates are carried 
out using an interactive Computer terminal. 
Data can be obtained as a printout or micro-
fiche or on magnetic tapes. 
Stored data are available on request to 
public health authorities, institutions, study 
groups of the International Committee on 
Taxonomy of Viruses and other Organiza-
t i o n , and on a limited basis to individuals. 
In addition, Software has been developed 
for a Vaccine data sheet based on the virus 
program. Data for each viral Vaccine pro-
duced will be collected. A short question-
naire has been prepared in Cooperation with 
several specialists in the field. Data collec-
tion on rabies vaccines has been started in 
collaboration with the WHO Mediterranean 
Zoonoses Centre, Athens. 
The following is a list of viruses in the data 
bank. 
Parvoviridae 
Minute virus of mice 
Bovine parvovirus 
Parvovirus H-l 
Porcine parvovirus 
Equine dependovirus 
Canine dependovirus 
Avian dependovirus 
Bovine dependovirus 
Parvovirus RT 
Rabbit parvovirus 
Aleutian disease virus 
Parvovirus LuIII 
Parvovirus TVX 
Feline panleukopenia virus 
Goose parvovirus 
Dependovirus types 1-4 
Adenoviridae 
Equine adenovirus 
Human adenovirus type 5 
Rabbit adenovirus 
Bovine adenovirus type 4 
Simian adenovirus types 1-24 
Tupaia adenovirus 
Herpesviridae 
Channel catfish virus 
Porcine cytomegalovirus 
Equine herpesvirus types 2 and 3 
Canine herpesvirus 
IBRIPV virus 
Marek's disease virus 
Turkey herpesvirus 
Pseudorabies virus 
Human cytomegalovirus 
Herpesvirus salmonis 
Guinea pig cytomegalovirus 
Guinea pig herpes-like virus 
Infectious laryngotracheitis virus 
Bovine mammilitis virus 
Poxviridae 
Vaccinia virus 
Iridoviridae 
African swine fever virus 
Picornaviridae 
Teschen talfan virus 
Foot-and-mouth disease virus, type O 
Caliciviridae 
Feline calicivirus 
Vesicular exanthema of swine virus 
Reoviridae 
Bovine rotavirus 
Chicken rotavirus 
Infectious bursal disease virus 
Ovine rotavirus 
Vertebrate Virus Data Bank 231 
Coronaviridae 
Enteritis of turkey virus 
Feline infectious Peritonitis virus 
Mouse hepatitis virus type 3 and type 4, 
strain A 59 
Sialodacryoadenitis virus 
Bovine Coronavirus 
Transmissible gastroenteritis virus 
Rat Coronavirus 
Hemagglutinating encephalomyelitis vi-
rus 
Canine Coronavirus 
Avian infectious bronchitis virus 
Human coronaviruses 229E and OC43 
Togaviridae 
Bovine viral diarrhea virus 
Border disease virus 
Equine arteritis virus 
Hog cholera virus 
Rhabdoviridae 
Spring viremia of carp virus 
Eel rhabdovirus 
Infectious hematopoietic necrosis virus 
Rabies virus 
Bovine ephemeral fever virus 
Bunyaviridae 
Nairobi sheep disease virus 
Orthomyxoviridae 
Influenzavirus types A, B, and C 
Paramyxoviridae 
Canine distemper virus 
Rinderpest virus 
Newcastle disease virus 
Peste des petits ruminants virus 
Avian paramyxovirus types 2-9 
Bovine respiratory syncytial virus 
Retroviridae 
Visna-maedi virus 
Equine infectious anemia virus 
Bovine leukemia virus 
Arenaviridae 
Lymphocytic choriomeningitis virus 
Nonclassified viruses 
Runde virus 
Marburg virus 


General Information on the Vertebrate Virus Data Bank "DAISY"

Open Access LMU

M 1 tfs^ 21/1/84 keleased January 1984 S. Karger Medical and Scientific Publishers Basel • München • Paris London New York Tokyo•Sydney Clinical Chemotherapy Edited by Helmut P. Kuemmerle Visiting Professor for Clinical Pharmacology at the Tokyo Medical College; Visiting Professor for Clinical Pharmacology at the College of Mediane, Hanyang University in Seoul/Corea; Specialist in Obstetrics and Gynecology, Clinical Pharmacology and Chemotherapy; Presi-dent of the International Society of Chemotherapy Applications for chemotherapy have witnessed incredible growth since the early 20th Century... this new three volume series „Clinical Chemotherapy" presents an authoritative Position and review of proven therapeutic concepts and recent developments in this field. 15% reduced preferential price for subscribers to this series Volume I: Fundamentals 1983. 503 pages, 181 figures, 73 tables cloth approx $ 96.00/DM 240,-(Pref. price approx. $ 82.00/DM 204,-) Upcoming volumes in the Clinical Chemotherapy series: Volume II: Antimicrobial Chemotherapy 1984. Cloth approx. $ 96.00/approx. DM 240,-(Pref. price approx. $ 82.00/approx. DM 204,-) Volume III: Antineoplastic Chemotherapy 1984. Cloth approx. $ 96.00/approx. DM 240,-(Pref. price approx. $ 82.00/approx. DM 204,-) Georg Thieme Verlag Stuttgart • New York F 83211 Bayen s Ohe Staaten - thofc Mär cnen V J Vol. 211, 1984 Editor-in-Chief J.L. Melnick, USA Associ&te Editor F. Rapp, USA Intervirology The Journal of the Virology Division, International Union of Microbiological Societies Section Editors* Structure of Viruses M.V. Nermut, UK (Section Editor) T.F. Anderson, USA S. Dales, Canada R.W. Hörne, UK F. A. Murphy, USA E. Norrby, Sweden G. Ruttkay-Nedecky, Czechoslovakia J. Skehel, UK D.W. Verwoerd, S. Africa Plant Virology A. Gibbs, Australia (Section Editor) J.B. Bancroft, UK R. Bercks, FRG H. Fraenkel-Conrat, USA R.W. Fulton, USA B. D. Harrison, UK Z. Hidaka, Japan L. Hirth, France R.J. Shepherd, USA V. Valenta, Czechoslovakia Invertebrate Virology J.F. Longworth, New Zealand (Section Editor) K. Aizawa, Japan L. Bailey, UK D. C. Kelly, UK E. Kurstak, Canada K. Maramorosch, USA C. C. Payne, UK C. Reinganum, Australia D. W. Roberts, USA R.R. Rueckert, USA C. Vago, France J.L. Vaughn, USA Füll addresses of the Editorial Board members may be obtained firom the office of the Editor-in-Chief or from the Publisher. Bacteriophage N.D. Zinder, USA (Section Editor) D. Botstein, USA D.E. Bradley, Canada A. Eisenstark, USA F. A. Eiserling, USA W. Fiers, Belgium R.M. Franklin, Switzerland D. M. Goldfarb, USSR R. Haselkorn, USA P.H. Hofschneider, FRG M. Schweiger, FRG E. R. Signer, USA Virus-Cell Relationship G. Klein, Sweden (Section Editor) R. Bablanian, USA F. Brown, UK R.W. Compans, USA A. Granoff, USA I. Grosser, France W.G. Laver, Australia L. Kjellen, Sweden T.C. Merigan, USA L. Montagnier, France B. Moss, USA W.C. Russell, UK R. Sheinin, Canada H. zur Hausen, FRG Replication ofAnimal Viruses D. W. Kingsbury, USA (Section Editor) V.l. Agol, USSR Y. Becker, Israel M. Bratt, USA E. Fanning, FRG M. Girard, France A. Graham, Canada A.S. Huang, USA W.K. Joklik, USA A. S. Kaplan, USA R.A. Lazzarini, USA J.V. Maizel, Jr., USA B. R. McAuslan, Australia L. Philipson, Sweden M.E. Reichmann, USA B. Roizman, USA R. Rott, FRG V. Stollar, USA P. Wildy, UK V.M. Zhdanov, USSR WIBIHB Genetics C R . Pringle, UK (Section Editor) Y. Ghendon, USSR H. Hanafusa, USA E.D. Kilbourne, USA S. Kit, USA J.F. Sambrook, USA J.H. Subak-Sharpe, UK P.K. Vogt, USA J. Zavada, Czechoslovakia Ecology/Epidemiology E. H. Lennette, USA (Section Editor) F. L. Black, USA D. Blaskovic, Czechoslovakia R.M. Chanock, USA F. Dekking, Netherlands R.W. Emmons, USA S. Gaidamovich, USSR N. Goldblum, Israel Huang Chen-hsiang, China K. Johnson, USA J.A.R. Miles, New Zealand N. Nathanson, USA W.E. Rawls, Canada L. Rosen, USA J. van der Veen, Netherlands H. von Magnus, Denmark H.A. Wenner, USA Oncology F. Rapp, USA (Section Editor) H. Bauer, FRG J.S. Butel, USA M.A. Epstein, UK R.C. Gallo, USA M. Hill, France Y. Ito, Japan A.J. Levine, USA J.A. Levy, USA P. Sheldrick, France P.G. Spear, USA J. Svoboda, Czechoslovakia G. Todaro, USA J. van der Noordaa, Netherlands P. Vigier, France Immunology N. Oker-Blom, Finland (Section Editor) A.C. Allison, UK F. Deinhardt, FRG S. Fazekas de St. Groth, Switzerland Huang Chen-hsiang, China D.T. Karzon, USA M.B.A. Oldstone, USA A.J. Rhodes, Canada N.J. Schmidt, USA V. Vonka, Czechoslovakia Comparative Virology F.A. Murphy, USA (Section Editor) E.G. Bade, FRG A.J.D. Bellen, Australia A.G. Bukrinskaya, USSR A. Gibbs, Australia B. D. Harrison, UK M.C. Horzinek, Netherlands W.K. Joklik, USA E. Kurstak, Canada W.G. Laver, Australia K. Maramorosch, USA C. C. Payne, UK R.E. Shope, USA P. Wildy, UK Taxonomy F. Brown, UK (Section Editor) P.A. Bachmann, FRG K.W. Buck, UK A. Eisenstark, USA R.I. Hamilton, Canada D. W. Kingsbury, USA J.F. Longworth, New Zealand S. Karger • Medical and Scientific Publishers • Basel • München • Paris • London • New York • Tokyo • Sydney Drug Dosage The authors and the publisher have exerted every eflbrt to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug forany change in indications and dos-age and for added warnings and precautions. This is par-ticularly important when the recommended agent is a new and/or infrequently employed drug. All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopy-ing, recording, microcopying, or by any information stor-age and retrieval System, without permission in writing from the publisher or, in the case of photocopying, direct payment of a specified fee to the Copyright Clearance Center (see 'Information for Readers and Subscribers'). © Copyright 1984 by S. Karger AG, P.O. Box, CH-4009 Basel (Switzerland) Printed in Switzerland by Graphische Betriebe Coop Schweiz, Basel Contents Vol. 21,1984 No. 1 Taxonomy Polydnaviridae - A Proposed Family of Insect Viruses with Segmented, Double-Stranded, Circular DNA Genomes Stoltz, D.B.; Krell, P.; Summers, M.D.; Vinson, S.B 1 Original Papers Ultrastructural Changes during Herpes Simplex Virus Type 2 Latency and Reactivation in vitro Hung, T.; Mummaw, J.G.; Wigdahl, B.L.; Fang, Z.Y.; Huaying, J.; Rapp, F 5 Candidate Products of Avian Myeloblastosis Virus Oncogene Region Produced by in vitro Translation of Genomic RNA Wright, S.E.; Harmon, S.A.; Smith, D.P.; Hayes, J.K.; Robertson, P.A.; Wayne, A.W. . 17 Variation in the Structure of Varicella-Zoster Virus DNA Ecker, J.R.; Kudler, L.; Hyman, R.W 25 Characterization of the Changuinola Serogroup Viruses (Reoviridae: Orbivirus) Travassos da Rosa, A.P.A.; Tesh, R.B.; Pinheiro, F.P.; Travassos da Rosa, J.F.S.; Peralta, P.H.; Knudson, D.L 38 Replication and Serial Passage of a Singly Enveloped Baculovirus of Orgyia leucostigma in Homologous Cell Lines Sohi, S.S.; Percy, J.; Arif, B.M.; Cunningham, J.C 50 No. 2 Original Papers Preclinical Changes in Weight of Scrapie-Infected Mice as a Function of Scrapie Agent-Mouse Strain Combination Carp, R.I.; Callahan, S.M.; Sersen, E.A.; Moretz, R.C 61 Sphingolipid Metabolism during Infection of Human Fibroblasts by Herpes Simplex Virus Type 1 Steinhart, W.L.; Busch, J.S.; Oettgen, J.P.; Howland, J.L 70 Mechanism of Persistence with Canine Distemper Virus: Difference between a Laboratory Strain and an Isolate from a Dog with Chronic Neurological Disease Tobler, L.H.; Imagawa, D.T 77 The Inability of in vitro Transforming SV40 Subgenomes to Cause Tumors in vivo Moyer, M.P.; Arizpe, H.; Sosa, A.; Pierson, K.; Moyer, R.C 87 Heterogeneity in Subregions of the Terminal Repeats of Herpes Simplex Virus Type 2 DNA Berg, F.M. van den; Ooyen, A.J.J. van; Volkers, H.; Walboomers, J.M.M 96 Characterization of Epstein-Barr Virus-Related Thymidine Kinase Induced in Nonproducer Cells by Superinfection or Chemical Treatment Mac Gabhann, P.; Sugawara, K.; Ito, Y 104 A Study of Measles Virus Antigens in Acutely and Persistently Infected Cells Using Mono-clonal Antibodies: Differences in the Accumulation of Certain Viral Proteins Giraudon, P.; Gerald, Ch.; Wild, T.F 110 IV Contents No. 3 Original Papers OKIO-Transformed Cell Lines: Viral Component Generation and Tumorigenicity Pfeifer-Ohlsson, S 121 Mode of Action of the Antiphytoviral Compound 2,4-Dioxohexahydro-l,3,5-triazine (5-Azadihydrouracil) Schuster, G.; Arenhövel, C 134 Effect of Acyclovir and Phosphonoformate on Cytomegalovirus Infection in Guinea Pigs Lucia, H.L.; Griffith, B.P.; Hsiung, G.D 141 Accumulation of Poliovirus Proteins in Uninfected Isolated HEp-2 Cell Nuclei in vitro Bossart, W.; Egger, D.; Rasser, Y.; Bienz, K 150 Glycine Mottle Virus, a Possible Member of the Tombusvirus Group Behncken, G.M.; Dale, J.L 159 Short Communications Characterization of a Cytoplasmic Polyhedrosis Virus Infecting Manduca sexta Galinski, M.S.; Kingan, T.; Rohrmann, G.F.; Martignoni, M.E.; Beaudreau, G.S 167 Protection Conferred against Junin Virus Infection in Rats Blejer, J.L.; Galassi, N.V.; Saavedra, V.M.; Nejamkis, M.R 174 Transplacental Infection in Guinea Pigs Inoculated with an Attenuated Strain of Junin Virus Boxaca, M.C.; Gömez, M.d.l.M.; Berria, M.I.; Iäcono, R.F 178 No. 4 Original Papers Relationship of Encephalomyocarditis Virus to Cricket Paralysis Virus of Insects Tinsley, T.W.; MacCallum, F.O.; Robertson, J.S.; Brown, F 181 Localization of Hepatitis A Virus Antigen to Specific Subcellular Fractions of Hepatitis-A-Infected Chimpanzee Liver Cells Khan, N.C.; Hollinger, F.B.; Melnick, J.L 187 Changes in Cellular DNA Sequence Adjacent to Integrated Viral Genome in Transplantable and Nontransplantable Guinea Pig Cells Transformed by SV40 Iwamura, Y.; Hamada, H.; Muramatsu, M.; Kato, K 195 Interaction of Autographa californica Nuclear Polyhedrosis Virus with Two Nonpermissive Cell Lines Gröner, A.; Granados, R.R.; Burand, J.P 203 Recognition of Host-Membrane Antigens in the Envelope of Measles Virions Armstrong, M.A.; Fräser, K.B.; Shirodaria, P.V 210 Priming of Bovine Interferons Lefkowitz, S.S.; Luna, V.E.R 221 Short Communications Specificity of the Actinomycin-D-Sensitive Function of Some RNA Plant Viruses Turner, M.S.; Dawson, W . 0 224 General Information on the Vertebrate Virus Data Bank 'DAISY': First Report Bachmann, P.A.; Eichhorn, W 229 Author Index 232 Subject Index 235 Intervirology 21: 229-231 (1984) © 1984 S. Karger AG, Basel 0300-5526/84/0214-0229S2.75/0 General Information on the Vertebrate Virus Data Bank 'DAISY': First Report Peter A. Bachmann, Werner Eichhorn World Health Organization Collaborating Centre for the Collection and Evaluation of Data on Comparative Virology, Munich, FRG The aims of the work at the Munich Cen-tre are to establish, collate and maintain de-tailed up-to-date information on viruses af-fecting animals and man and to establish a data bank on viruses of vertebrates in a com-puterized System. For this purpose, a ques-tionnaire has been developed containing over 200 items, including relevant references. Specialists fill out questionnaires on a certain virus, which are then put into the data bank. The virus questionnaires principally consist of five sections: general data (taxonomy, his-tory, availability of reagents); viral proper-ties (nucleic acid, proteins, lipids, carbohy-drates, physicochemical relationships); di-agnosis (viral and serological diagnosis); natural and experimental infection (trans-mission, course of infection, immunological response); and selected references. A special Computer program has been de-veloped for the virus data bank employing the programming language PASCAL and a strictly sequential file concept. This System Address inquiries fo:Dr. P.A. Bachmann, Institute for Medical Microbiology, Infectious and Epidemie Diseases, Veterinary Faculty, University of Munich, Veterinärstrasse 13, D-8000 Munich 22 (FRG) Received: September 20, 1983 allows for unlimited corrections to be made on each questionnaire, while other files can be used for retrieval. The data bank has four independent features: input and update of questionnaires; entering of questionnaires (updated) into the data bank set; selection of a virus questionnaire and its transfer to the input file (update); and retrieval. The data bank program is compatible with most of the commercially available Systems. All data are stored on magnetic dises. There is a wide ränge of options for the retrieval of data: retrieval of completed virus data ques-tionnaires; retrieval of certain parts of the questionnaires; retrieval of answers to a single or multiple questions for all viruses in the data bank; and multiple linkage analysis for different data items (comparison of mul-tiple data from all viruses). Piain language is used for all virus data and, to facilitate retrieval and linkage analy-sis, a Standard list of key words has been compiled enabling the use of the data bank without complicated training. Regulär updating of the virus question-naires in the data bank is planned at yearly intervals. Since new items (questions) will have to be introduced into the questionnaire, and others presently listed in the question-naire deleted, Software has been developed 230 Bachmann'Eichhorn to include these additional Steps in the pro-gram. This permits changes in the present concept as well as in virus questionnaires already stored in the data bank. Retrieval, input and Updates are carried out using an interactive Computer terminal. Data can be obtained as a printout or micro-fiche or on magnetic tapes. Stored data are available on request to public health authorities, institutions, study groups of the International Committee on Taxonomy of Viruses and other Organiza-t i o n , and on a limited basis to individuals. In addition, Software has been developed for a Vaccine data sheet based on the virus program. Data for each viral Vaccine pro-duced will be collected. A short question-naire has been prepared in Cooperation with several specialists in the field. Data collec-tion on rabies vaccines has been started in collaboration with the WHO Mediterranean Zoonoses Centre, Athens. The following is a list of viruses in the data bank. Parvoviridae Minute virus of mice Bovine parvovirus Parvovirus H-l Porcine parvovirus Equine dependovirus Canine dependovirus Avian dependovirus Bovine dependovirus Parvovirus RT Rabbit parvovirus Aleutian disease virus Parvovirus LuIII Parvovirus TVX Feline panleukopenia virus Goose parvovirus Dependovirus types 1-4 Adenoviridae Equine adenovirus Human adenovirus type 5 Rabbit adenovirus Bovine adenovirus type 4 Simian adenovirus types 1-24 Tupaia adenovirus Herpesviridae Channel catfish virus Porcine cytomegalovirus Equine herpesvirus types 2 and 3 Canine herpesvirus IBRIPV virus Marek's disease virus Turkey herpesvirus Pseudorabies virus Human cytomegalovirus Herpesvirus salmonis Guinea pig cytomegalovirus Guinea pig herpes-like virus Infectious laryngotracheitis virus Bovine mammilitis virus Poxviridae Vaccinia virus Iridoviridae African swine fever virus Picornaviridae Teschen talfan virus Foot-and-mouth disease virus, type O Caliciviridae Feline calicivirus Vesicular exanthema of swine virus Reoviridae Bovine rotavirus Chicken rotavirus Infectious bursal disease virus Ovine rotavirus Vertebrate Virus Data Bank 231 Coronaviridae Enteritis of turkey virus Feline infectious Peritonitis virus Mouse hepatitis virus type 3 and type 4, strain A 59 Sialodacryoadenitis virus Bovine Coronavirus Transmissible gastroenteritis virus Rat Coronavirus Hemagglutinating encephalomyelitis vi-rus Canine Coronavirus Avian infectious bronchitis virus Human coronaviruses 229E and OC43 Togaviridae Bovine viral diarrhea virus Border disease virus Equine arteritis virus Hog cholera virus Rhabdoviridae Spring viremia of carp virus Eel rhabdovirus Infectious hematopoietic necrosis virus Rabies virus Bovine ephemeral fever virus Bunyaviridae Nairobi sheep disease virus Orthomyxoviridae Influenzavirus types A, B, and C Paramyxoviridae Canine distemper virus Rinderpest virus Newcastle disease virus Peste des petits ruminants virus Avian paramyxovirus types 2-9 Bovine respiratory syncytial virus Retroviridae Visna-maedi virus Equine infectious anemia virus Bovine leukemia virus Arenaviridae Lymphocytic choriomeningitis virus Nonclassified viruses Runde virus Marburg virus 

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General Information on the Vertebrate Virus Data Bank "DAISY"

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