Estudi bibliomètric primer trimestre 2014. EETAC

El present document recull les publicacions indexades a la base de dades Scopus durant el període comprès entre el mesos de gener a abril de l’any 2014, escrits per autors pertanyents a l’EETAC. Es presenten les dades recollides segons la font on s’ha publicat, els autors que han publicat, i el tipus de document publicat. S’hi inclou un annex amb la llista de totes les referències bibliogràfiques publicades.El present document recull les publicacions indexades a la base de dades Scopus durant el període comprès entre el mesos de gener a abril de l’any 2014, escrits per autors pertanyents a l’EETAC. Es presenten les dades recollides segons la font on s’ha publicat, els autors que han publicat, i el tipus de document publicat. S’hi inclou un annex amb la llista de totes les referències bibliogràfiques publicades.Postprint (published version

Analysis and Design of RF Power and Data Link Using Amplitude Modulation of Class-E for a Novel Bone Conduction Implant

This paper presents analysis and design of a radio frequency power and data link for a novel Bone Conduction Implant (BCI) system. Patients with conductive and mixed hearing loss and single-sided deafness can be rehabilitated by bone-anchored hearing aids (BAHA). Whereas the conventional hearing aids transmit sound to the tympanic membrane via air conduction, the BAHA transmits sound via vibrations through the skull directly to the cochlea. It uses a titanium screw that penetrates the skin and needs life-long daily care; it may cause skin infection and redness. The BCI is developed as an alternative to the percutaneous BAHA since it leaves the skin intact. The BCI comprises an external audio processor with a transmitter coil and an implanted unit called the bridging bone conductor with a receiver coil. Using amplitude modulation of the Class-E power amplifier that drives the inductive link, the sound signal is transmitted to the implant through the intact skin. It was found that the BCI can generate enough output force level for candidate patients. Maximum power output of the BCI was designed to occur at 5-mm skin thickness and the variability was within 1.5 dB for 1–8-mm skin thickness variations

Master of Science

thesisFully integrated, implantable, and wireless neural interface systems typically re-quire a forward data link in addition to the telemetry link that transmits data from the chip. One popular way to create this forward data link is to amplitude modulate the magnetic fi eld of the inductive link that provides the device with wireless power. However, the limitations of these channels when loaded with a recti fier and amplitude modulated have not previously been characterized, and this lack of understanding caused previous versions of the Integrated Neural Interface (INI) to have forward data communication issues, which needed to be corrected for the next generation of the device, INIR8. This thesis first develops an analytical method of characterizing this sort of wireless channel. It then shows measurement data that verifies the validity of the model in the desired region of operation. The available bandwidth as determined by this analytical method, and confirmed by simulation, is insufficient for many applications. Therefore, the next subject of this thesis is to increase the data rate beyond what the bandwidth of the system can intrinsically support by using an equalization technique. This technique is shown to support very robust data recovery under a variety of operating conditions and to data rates much higher than otherwise possible. Another way to improve the reliability of data recovery is to develop a robust digital control system with error detection capabilities. This was done for INIR8, and works very reliably. The end result of this eff ort is a very robust forward data communication in INIR8, as well as a new analytical method for characterizing inductively coupled channels with certain loads and modulation techniques

An energy-efficient wireless data link for implantable electronics

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2009.Cataloged from PDF version of thesis.Includes bibliographical references (p. 101-103).Low-power wireless links are important for the development of long-term implantable neural prostheses. Furthermore, in implanted systems with many neural recording electrodes, the data rate of the wireless link will need to be quite high since each recording electrode can produce about 120 kbps of data. For low-power operation, inductively-coupled near-field wireless links have shown great promise and were used to develop a power-efficient data link for biomedical implants. A prototype bi-directional, half-duplex wireless link based on inductive coupling was designed in a 0.18 [mu]m process. The uplink (i.e. data transmission from the internal transceiver) was designed to use an impedance modulation strategy. Since this technique only requires a single local oscillator (LO) in the external transceiver, the energy expenditure of the implanted transceiver is minimized. Simulated uplink data transfer rates of up to 10 Mbps has been shown. A PWM based ASK coding strategy was used for the downlink (i.e. data transmission to the implanted device). The downlink is able to achieve a data transfer rate of up to 1.5 Mbps. A technique to reduce BER of inductive coupling links due to pulse-width distortion effects by pre-distorting the transmitted data is also presented. A calibration technique to reduce the resonant frequency mismatch between the two magnetically coupled resonators is also shown.by Daniel Prashanth Kumar.S.M

Wireless Telemetry System for Implantable Sensors

Advanced testing of medical treatments involves experimentation on small laboratory animals, such as genetically modified mice. These subjects are used to help researchers develop medication and cures for humans. To understand the effects of the treatments, innovative telemetry systems are developed, that enable remote real-time cardiac monitoring. The latest research in the field of cardiac monitoring has revealed two major limitations with wireless implantable systems: a) the current size of implantable electronics limits the physical size of the system to larger subjects; and b) the systems only interface with one sensor type (e.g., pressure sensor only). This research focuses on the design of a wireless telemetry system architecture, intended to retrieve blood pressure and volume data. A physical prototype is created that is 2.475 cm3 and weights 4.01 g. This thesis will enable a path towards miniaturization, leading to the incorporation of a wireless system into small laboratory animals

Design of Beam Steering Electronic Circuits for Medical Applications

This thesis deals with the theory and design of a hemispherical antenna array circuit that is capable to operate in the intermediate zones. By doing that, this array can be used in Hyperthermia Treatment for Brain Cancer in which the aim is to noninvasively focus the fields at microwave frequencies to the location of the tumor cells in the brain. Another possible application of the array is to offer an alternative means of sustaining Deep Brain Stimulation other than using the traditional (surgical) approach. The new noninvasive technique is accomplished by the use of a hemispherical antenna array placed on the human's head. The array uses a new beamforming technique that achieves 3 dimensional beamforming or focusing of the magnetic field of antennas to desired points in the brain to achieve either cell death by temperature rise (Hyperthermia Application) or to cause brain stimulation and hopefully alleviate the affects of Parkinson's Disease (Deep Brain Stimulation). The main obstacle in this design was that the far field approximation that is usually used when designing antenna arrays does not apply in this case since the hemispherical array is in close proximity to where the magnetic field is desired to be focused. The antenna array problem is approached as a boundary-valued problem with the human head being modeled as a three layered hemisphere. The exact expressions for electromagnetic fields are derived. Health issues such as electric field exposure and specific absorption rate (SAR) are considered. After developing the main antenna and beamforming theory, a neural network is designed to accomplish the beamforming technique used. The radio-frequency (RF) transmitter was designed to transmit the fields at a frequency of 1.8 GHz. The antenna array can also be used as a receiver. The antenna and beamforming theory is presented. A new reception technique is shown which enables the array to receive multiple magnetic field sources from within the hemispherical surface. The receiver is designed to operate at 500 kHz with the RF receiver circuit designed to receive any signal from within the hemispherical surface at a frequency of 500 kHz

MRI-Based Communication with Untethered Intelligent Medical Microrobots

RESUME Les champs magnétiques présent dans un système clinique d’Imagerie par Résonance Magnétique (IRM) peuvent être exploités non seulement, afin d’induire une force de déplacement sur des microrobots magnétiques tout en permettant l’asservissement de leur position - une technique connue sous le nom de Navigation par Résonance Magnétique (NRM), mais aussi pour mettre en œuvre un procédé de communication. Pour des microrobots autonomes équipés de senseurs ayant un certain niveau d'intelligence et opérant à l'intérieur du corps humain, la puissance de transmission nécessaire pour communiquer des informations à un ordinateur externe par des méthodes présentement connues est insuffisante. Dans ce travail, une technique est décrite où une telle perte de puissance d'émission en raison de la mise à l'échelle de ces microrobots peut être compensée par le scanner IRM agissant aussi comme un récepteur très sensible. La technique de communication prend la forme d'une modification de la fréquence du courant électrique circulant le long d'une bobine miniature incorporé dans un microrobot. La fréquence du courant électrique peut être réglée à partir d'une entrée de seuil prédéterminée du senseur mis en place sur le microrobot. La fréquence devient alors corrélée à l’information de l’état du senseur recueilli par le microrobot et elle est déterminée en utilisant l'IRM. La méthode proposée est indépendante de la position et l'orientation du microrobot et peut être étendue à un grand nombre de microrobots pour surveiller et cartographier les conditions physiologiques spécifiques dans une région plus vaste à n’importe quelle profondeur à l'intérieur du corps.----------ABSTRACT The magnetic environment provided by a clinical Magnetic Resonance Imaging (MRI) scanner can be exploited to not only induce a displacement force on magnetic microrobots while allowing MR-tracking for serving control purpose or positional assessment - a technique known as Magnetic Resonance Navigation (MRN), but also for implementing a method of communication with intelligent microrobots. For untethered sensory microrobots having some level of intelligence and operating inside the body, the transmission power necessary to communicate information to an external computer via known methods is insufficient. In this work, a technique is described where such loss of transmission power due to the scaling of these microrobots can be compensated by the same MRI scanner acting as a more sensitive receiver. A communication scheme is implemented in the form of a frequency alteration in the electrical current circulating along a miniature coil embedded in a microrobot. The frequency of the electrical current could be regulated from a predetermined sensory threshold input implemented on the microrobot. Such a frequency provides information on the level of sensory information gathered by the microrobot, and it is determined using MR imaging. The proposed method is independent of the microrobot's position and orientation and can be extended to a larger number of microrobots for monitoring and mapping specific physiological conditions inside a larger region at any depths within the body

Investigation of high bandwith biodevices for transcutaneous wireless telemetry

PhD ThesisBIODEVICE implants for telemetry are increasingly applied today in various areas applications. There are many examples such as; telemedicine, biotelemetry, health care, treatments for chronic diseases, epilepsy and blindness, all of which are using a wireless infrastructure environment. They use microelectronics technology for diagnostics or monitoring signals such as Electroencephalography or Electromyography. Conceptually the biodevices are defined as one of these technologies combined with transcutaneous wireless implant telemetry (TWIT). A wireless inductive coupling link is a common way for transferring the RF power and data, to communicate between a reader and a battery-less implant. Demand for higher data rate for the acquisition data returned from the body is increasing, and requires an efficient modulator to achieve high transfer rate and low power consumption. In such applications, Quadrature Phase Shift Keying (QPSK) modulation has advantages over other schemes, and double the symbol rate with respect to Binary Phase Shift Keying (BPSK) over the same spectrum band. In contrast to analogue modulators for generating QPSK signals, where the circuit complexity and power dissipation are unsuitable for medical purposes, a digital approach has advantages. Eventually a simple design can be achieved by mixing the hardware and software to minimize size and power consumption for implantable telemetry applications. This work proposes a new approach to digital modulator techniques, applied to transcutaneous implantable telemetry applications; inherently increasing the data rate and simplifying the hardware design. A novel design for a QPSK VHDL modulator to convey a high data rate is demonstrated. Essentially, CPLD/FPGA technology is used to generate hardware from VHDL code, and implement the device which performs the modulation. This improves the data transmission rate between the reader and biodevice. This type of modulator provides digital synthesis and the flexibility to reconfigure and upgrade with the two most often languages used being VHDL and Verilog (IEEE Standard) being used as hardware structure description languages. The second objective of this thesis is to improve the wireless coupling power (WCP). An efficient power amplifier was developed and a new algorithm developed for auto-power control design at the reader unit, which monitors the implant device and keeps the device working within the safety regulation power limits (SAR). The proposed system design has also been modeled and simulated with MATLAB/Simulink to validate the modulator and examine the performance of the proposed modulator in relation to its specifications.Higher Education Ministry in Liby

Low power circuits and systems for wireless neural stimulation

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 155-161).Electrical stimulation of tissues is an increasingly valuable tool for treating a variety of disorders, with applications including cardiac pacemakers, cochlear implants, visual prostheses, deep brain stimulators, spinal cord stimulators, and muscle stimulators. Brain implants for paralysis treatments are increasingly providing sensory feedback via neural stimulation. Within the field of neuroscience, the perturbation of neuronal circuits wirelessly in untethered, freely-behaving animals is of particular importance. In implantable systems, power consumption is often the limiting factor in determining battery or power coil size, cost, and level of tissue heating, with stimulation circuitry typically dominating the power budget of the entire implant. Thus, there is strong motivation to improve the energy efficiency of implantable electrical stimulators. In this thesis, I present two examples of low-power tissue stimulators. The first type is a wireless, low-power neural stimulation system for use in freely behaving animals. The system consists of an external transmitter and a miniature, implantable wireless receiver-and-stimulator utilizing a custom integrated chip built in a standard 0.5 ptm CMOS process. Low power design permits 12 days of continuous experimentation from a 5 mAh battery, extended by an automatic sleep mode that reduces standby power consumption by 2.5x. To test this device, bipolar stimulating electrodes were implanted into the songbird motor nucleus HVC of zebra finches. Single-neuron recordings revealed that wireless stimulation of HVC led to a strong increase of spiking activity in its downstream target, the robust nucleus of the arcopallium (RA). When this device was used to deliver biphasic pulses of current randomly during singing, singing activity was prematurely terminated in all birds tested. The second stimulator I present is a novel, energy-efficient electrode stimulator with feedback current regulation. This stimulator uses inductive storage and recycling of energy based on a dynamic power supply to drive an electrode in an adiabatic fashion such that energy consumption is minimized. Since there are no explicit current sources or current limiters, wasteful energy dissipation across such elements is naturally avoided. The stimulator also utilizes a shunt current-sensor to monitor and regulate the current through the electrode via feedback, thus enabling flexible and safe stimulation. The dynamic power supply allows efficient transfer of energy both to and from the electrode, and is based on a DC-DC converter topology that is used in a bidirectional fashion. In an exemplary electrode implementation, I show how the stimulator combines the efficiency of voltage control and the safety and accuracy of current control in a single low-power integrated-circuit built in a standard 0.35 pm CMOS process. I also perform a theoretical analysis of the energy efficiency that is in accord with experimental measurements. In its current proof-of-concept implementation, this stimulator achieves a 2x-3x reduction in energy consumption as compared to a conventional current-source-based stimulator operating from a fixed power supply.by Scott Kenneth Arfin.Ph.D

Asservissement de l'énergie inductive transmise aux implants électroniques

RÉSUMÉ Ce mémoire concerne le domaine d’alimentation énergétique des implants médicaux électroniques (IME). L’alimentation des IME par couplage inductif a toujours été appréciée pour sa biocompatibilité et sa capacité à transmettre une quantité d’énergie suffisante aux implants électroniques. Bien que cette méthode fût introduite il y a longtemps, plusieurs défis restent à relever. Le défi majeur est la sensibilité de l’efficacité du transfert d’énergie à la variation de certains paramètres du lien comme le facteur de couplage entre les bobines, la charge du côté récepteur et l’inductance des bobines. Une variation de l’un de ces paramètres est en mesure d’altérer la fréquence de résonance primaire et réduire en conséquence la quantité d’énergie transférée vers l’IME. Dans ce contexte, nous présentons une nouvelle technique pour compenser la variation des paramètres du lien inductif. Elle permet de maintenir l’état de résonance dans le transmetteur et d’assurer une meilleure transmission d’énergie en dépit de ces variations. Un transmetteur d’énergie inductive asservi est alors proposé. Ce système est transportable et est alimenté par des batteries rechargeables. Il est composé d’un transmetteur d’énergie inductive classique et d’une boucle d’asservissement. Le transmetteur classique émet un champ inductif (ou champ magnétique alternatif) grâce à un oscillateur à quartz, un amplificateur de puissance (AP) de classe E et un circuit résonant primaire constitué d’un condensateur et d’une bobine d’émission. La boucle d’asservissement, quant à elle, sert à compenser les variations des paramètres du lien capables d’altérer la fréquence de résonance du circuit primaire. La boucle comporte principalement un bloc de détection de la tension aux bornes de la bobine d’émission (image de la puissance à transférer vers l’IME) et un micro moteur pas-à-pas à haute résolution qui agit sur le condensateur de résonance primaire et indirectement sur la fréquence de résonance. Le système proposé utilise une fréquence de fonctionnement de 13,56 MHz réservée aux applications industrielles, scientifiques et médicales (ISM).----------ABSTRACT This Master thesis deals with energy transfer systems dedicated to electronic medical implants (EMI). Powering EMIs by inductive link has always been prized for its biocompatibility and ability to transmit appropriate energy to electronic implants. Although this method was introduced a long time ago, several challenges still remain. The main challenge is the sensitivity of the energy transfer efficiency to the variation of some link parameters, such as the coupling factor between the coils, the load on the receiver side, and the coils inductances. A variation of any of these parameters is able to alter the primary resonant frequency and consequently reduce the amount of energy transferred to the EMI. In this context, we present a new method to compensate for variations of the inductive link parameters. This method maintains the resonant state in the transmitter and therefore ensures better energy transmission despite these variations. A controlled inductive power transmitter is then proposed. This system is portable and is powered by rechargeable batteries. It is composed of a conventional inductive energy transmitter and a feedback loop. The conventional transmitter emits an inductive field (or AC magnetic field) using a crystal oscillator, a class E power amplifier (PA) and a resonant primary circuit. The control loop is in turn used to compensate for the variations of the link parameters which are able to alter the resonant frequency of the primary circuit. The loop includes mainly a primary coil voltage detector (for sensing the power transferred to the EMI) and a high resolution micro stepper motor which controls the resonant capacitor and indirectly the primary resonance frequency. The proposed system uses an operating frequency of 13.56 MHz reserved for industrial, scientific and medical (ISM) applications. This frequency offers as well a good compromise between compatibility with the biological environment and the transmission range. Given that the proposed system is located outside the human body and that the class E amplifier generates a fairly high power, the prototype was performed on a printed circuit board using commercial discrete components