A Robust Cardiovascular Disease Predictor Based on Genetic Feature Selection and Ensemble Learning Classification

Timely detection of heart diseases is crucial for treating cardiac patients prior to the occurrence of any fatality. Automated early detection of these diseases is a necessity in areas where specialized doctors are limited. Deep learning methods provided with a decent set of heart disease data can be used to achieve this. This article proposes a robust heart disease prediction strategy using genetic algorithms and ensemble deep learning techniques. The efficiency of genetic algorithms is utilized to select more significant features from a high-dimensional dataset, combined with deep learning techniques such as Adaptive Neuro-Fuzzy Inference System (ANFIS), Multi-Layer Perceptron (MLP), and Radial Basis Function (RBF), to achieve the goal. The boosting algorithm, Logit Boost, is made use of as a meta-learning classifier for predicting heart disease. The Cleveland heart disease dataset found in the UCI repository yields an overall accuracy of 99.66%, which is higher than many of the most efficient approaches now in existence

Implementing decision tree-based algorithms in medical diagnostic decision support systems

As a branch of healthcare, medical diagnosis can be defined as finding the disease based on the signs and symptoms of the patient. To this end, the required information is gathered from different sources like physical examination, medical history and general information of the patient. Development of smart classification models for medical diagnosis is of great interest amongst the researchers. This is mainly owing to the fact that the machine learning and data mining algorithms are capable of detecting the hidden trends between features of a database. Hence, classifying the medical datasets using smart techniques paves the way to design more efficient medical diagnostic decision support systems. Several databases have been provided in the literature to investigate different aspects of diseases. As an alternative to the available diagnosis tools/methods, this research involves machine learning algorithms called Classification and Regression Tree (CART), Random Forest (RF) and Extremely Randomized Trees or Extra Trees (ET) for the development of classification models that can be implemented in computer-aided diagnosis systems. As a decision tree (DT), CART is fast to create, and it applies to both the quantitative and qualitative data. For classification problems, RF and ET employ a number of weak learners like CART to develop models for classification tasks. We employed Wisconsin Breast Cancer Database (WBCD), Z-Alizadeh Sani dataset for coronary artery disease (CAD) and the databanks gathered in Ghaem Hospital’s dermatology clinic for the response of patients having common and/or plantar warts to the cryotherapy and/or immunotherapy methods. To classify the breast cancer type based on the WBCD, the RF and ET methods were employed. It was found that the developed RF and ET models forecast the WBCD type with 100% accuracy in all cases. To choose the proper treatment approach for warts as well as the CAD diagnosis, the CART methodology was employed. The findings of the error analysis revealed that the proposed CART models for the applications of interest attain the highest precision and no literature model can rival it. The outcome of this study supports the idea that methods like CART, RF and ET not only improve the diagnosis precision, but also reduce the time and expense needed to reach a diagnosis. However, since these strategies are highly sensitive to the quality and quantity of the introduced data, more extensive databases with a greater number of independent parameters might be required for further practical implications of the developed models

Deep Learning Paradigm and Its Bias for Coronary Artery Wall Segmentation in Intravascular Ultrasound Scans: A Closer Look

Background and motivation: Coronary artery disease (CAD) has the highest mortality rate; therefore, its diagnosis is vital. Intravascular ultrasound (IVUS) is a high-resolution imaging solution that can image coronary arteries, but the diagnosis software via wall segmentation and quantification has been evolving. In this study, a deep learning (DL) paradigm was explored along with its bias. Methods: Using a PRISMA model, 145 best UNet-based and non-UNet-based methods for wall segmentation were selected and analyzed for their characteristics and scientific and clinical validation. This study computed the coronary wall thickness by estimating the inner and outer borders of the coronary artery IVUS cross-sectional scans. Further, the review explored the bias in the DL system for the first time when it comes to wall segmentation in IVUS scans. Three bias methods, namely (i) ranking, (ii) radial, and (iii) regional area, were applied and compared using a Venn diagram. Finally, the study presented explainable AI (XAI) paradigms in the DL framework. Findings and conclusions: UNet provides a powerful paradigm for the segmentation of coronary walls in IVUS scans due to its ability to extract automated features at different scales in encoders, reconstruct the segmented image using decoders, and embed the variants in skip connections. Most of the research was hampered by a lack of motivation for XAI and pruned AI (PAI) models. None of the UNet models met the criteria for bias-free design. For clinical assessment and settings, it is necessary to move from a paper-to-practice approach

The methods of duo output neural network ensemble for prediction of coronary heart disease

The occurrence of Coronary heart disease (CHD) is hard to predict yet, but the assessment of CHD risk for the next ten years is possible. The prediction of coronary heart disease can be modelled using multi-layer perceptron neural network (MLP-ANN). Prediction model with MLP-ANN has either positive or negative CHD output, which is a binary classification. A prediction model with binary classification requires determination of threshold value before the classification process which increases the uncertainty in the classification process. Another weakness of the MLP-ANN model is the presence of overfitting. This study proposes a prediction model for coronary heart disease using the duo output artificial neural network ensemble (DOANNE) method to overcome the problems of overfitting and uncertainty of classification in MLP-ANN. This research method was divided into several stages, namely data acquisition, pre-processing, modelling into DOANNE, neural network ensemble training with Levenberg-Marquard (LM) algorithm, system performance testing, and evaluation. The results of the study showed that the use of DOANNE-LM method was able to provide a significant improvement from the MLP-ANN method, indicated by the results of statistical tests with p-value <0.05

Detecting Heart Attacks Using Learning Classifiers

Cardiovascular diseases (CVDs) have emerged as a critical global threat to human life. The diagnosis of these diseases presents a complex challenge, particularly for inexperienced doctors, as their symptoms can be mistaken for signs of aging or similar conditions. Early detection of heart disease can help prevent heart failure, making it crucial to develop effective diagnostic techniques. Machine Learning (ML) techniques have gained popularity among researchers for identifying new patients based on past data. While various forecasting techniques have been applied to different medical datasets, accurate detection of heart attacks in a timely manner remains elusive. This article presents a comprehensive comparative analysis of various ML techniques, including Decision Tree, Support Vector Machines, Random Forest, Extreme Gradient Boosting (XGBoost), Adaptive Boosting, Multilayer Perceptron, Gradient Boosting, K-Nearest Neighbor, and Logistic Regression. These classifiers are implemented and evaluated in Python using data from over 300 patients obtained from the Kaggle cardiovascular repository in CSV format. The classifiers categorize patients into two groups: those with a heart attack and those without. Performance evaluation metrics such as recall, precision, accuracy, and the F1-measure are employed to assess the classifiers’ effectiveness. The results of this study highlight XGBoost classifier as a promising tool in the medical domain for accurate diagnosis, demonstrating the highest predictive accuracy (95.082%) with a calculation time of (0.07995 sec) on the dataset compared to other classifiers

A STUDY OF HEART DISEASE DIAGNOSIS USING MACHINE LEARNING AND DATA MINING

Heart disease is the leading cause of death for people around the world today. Diagnosis for various forms of heart disease can be detected with numerous medical tests, however, predicting heart disease without such tests is very difficult. Machine learning can help process medical big data and provide hidden knowledge which otherwise would not be possible with the naked eye. The aim of this project is to explore how machine learning algorithms can be used in predicting heart disease by building an optimized model. The research questions are; 1) What Machine learning algorithms are used in the diagnosis of heart disease? 2) How can Machine Learning techniques be used to minimize misdiagnosis (additional tests, and wrong treatment all resulting in greater monetary impact to the patient), 3) How can Machine Learning be used to detect early abnormalities, thus benefiting both patients and the healthcare system? We collected our dataset from the UCI repository and used Random Forest Classification algorithm for predicting heart disease. Then, we modified one of the hyperparameters called ‘N_Estimator’ to improve the model further. The findings and conclusion for each question are; 1) Machine learning algorithms used in predicting heart disease are Naïve Bayes, Decision Trees, Support Vector Machine, Bagging and Boosting, and RandomForest, concluding that these algorithms can achieve high accuracy in predicting heart disease. 2) Machine learning algorithms can analyze a large amount of data to assist medical professionals in making more informed decisions cost-effectively. 3) Machine Learning algorithms allowed us to analyze clinical data, draw relationships between diagnostic variables, design the predictive model, and tests it against the new case. The predictive model achieved an accuracy of 89.4 percent using RandomForest Classifier’s default setting to predict heart diseases. Furthermore, emerging areas for future research that emerged from this study include the opportunity for training and testing using our model with a larger dataset and modifying different hyperparameters for further improvement

Classification Model for Meticulous Presaging of Heart Disease Detection through SDA and NCA using Machine learning :CMSDANCA

For the design and implementation of CDSS, computation time and prognostic accuracy are very important. To analyze the large collection of a dataset for detecting and diagnosis disease ML techniques are used. According to the reports of World Health Organizations, HD is a major cause of death and killer in urban and rural areas or worldwide. The main reason for this is a shortage of doctors and delay in the diagnosis. In this research work, heart disease is a diagnosis by the data mining techniques and used the clinical parameters of patients for early stages diagnosis. The intend of this learning to develop a representation that relies on the prediction method for coronary heart disease. This proposed work used the approach of self-diagnosis Algorithm, Fuzzy Artificial neural network, and NCA & PCA and imputation methods. By the use of this technique computation time for prediction of Coronary HD can be reduced. For the implementation of this the two datasets are using such as Cleveland and Statlog datasets that is collected from the UCI kaggle the ML repository. The datasets for the disease prediction measure are used to accurately calculate the difference between variables and to determine whether they are correlated or not. For this classification model, the performance measure is calculated in requisites of their accuracy, precision, recall, and specificity. This approach is evaluated on the heart disease datasets for improving the accuracy performance results obtained. The outcome for KNN+SDA+NCA+FuzzyANN for Cleveland dataset accuracy achieved 98.56 %.and for Statlog dataset 98.66 %.

Predicting Arrhythmia Based on Machine Learning Using Improved Harris Hawk Algorithm

Arrhythmia disease is widely recognized as a prominent and lethal ailment on a global scale, resulting in a significant number of fatalities annually. The timely identification of this ailment is crucial for preserving individuals' lives. Machine Learning (ML), a branch of artificial intelligence (AI), has emerged as a highly efficient and cost-effective method for illness detection. The objective of this work is to develop a machine learning (ML) model capable of accurately predicting heart illness by using the Arrhythmia disease dataset, with the purpose of achieving optimal performance. The performance of the model is greatly influenced by the selection of the machine learning method and the features in the dataset for training purposes. In order to mitigate the issue of overfitting caused by the high dimensionality of the features in the Arrhythmia dataset, a reduction of the dataset to a lower dimensional subspace was performed via the improved Harris hawk optimization algorithm (iHHO). The Harris hawk algorithm exhibits a rapid convergence rate and possesses a notable degree of adaptability in its ability to identify optimal characteristics. The performance of the models created with the feature-selected dataset using various machine learning techniques was evaluated and compared. In this work, total seven classifiers like SVM, GB, GNB, RF, LR, DT, and KNN are used to classify the data produced by the iHHO algorithm. The results clearly show the improvement of 3%, 4%, 4%, 9%, 8%, 3%, and 9% with the classifiers KNN, RF, GB, SVM, LR, DT, and GNB respectively

An Intelligent Decision Support Ensemble Voting Model for Coronary Artery Disease Prediction in Smart Healthcare Monitoring Environments

Coronary artery disease (CAD) is one of the most common cardiac diseases worldwide and causes disability and economic burden. It is the world's leading and most serious cause of mortality, with approximately 80% of deaths reported in low- and middle-income countries. The preferred and most precise diagnostic tool for CAD is angiography, but it is invasive, expensive, and technically demanding. However, the research community is increasingly interested in the computer-aided diagnosis of CAD via the utilization of machine learning (ML) methods. The purpose of this work is to present an e-diagnosis tool based on ML algorithms that can be used in a smart healthcare monitoring system. We applied the most accurate machine learning methods that have shown superior results in the literature to different medical datasets such as RandomForest, XGboost, MLP, J48, AdaBoost, NaiveBayes, LogitBoost, KNN. Every single classifier can be efficient on a different dataset. Thus, an ensemble model using majority voting was designed to take advantage of the well-performed single classifiers, Ensemble learning aims to combine the forecasts of multiple individual classifiers to achieve higher performance than individual classifiers in terms of precision, specificity, sensitivity, and accuracy; furthermore, we have benchmarked our proposed model with the most efficient and well-known ensemble models, such as Bagging, Stacking methods based on the cross-validation technique, The experimental results confirm that the ensemble majority voting approach based on the top 3 classifiers: MultilayerPerceptron, RandomForest, and AdaBoost, achieves the highest accuracy of 88,12% and outperforms all other classifiers. This study demonstrates that the majority voting ensemble approach proposed above is the most accurate machine learning classification approach for the prediction and detection of coronary artery disease.Comment: International Journal of Advanced Computer Science and Applications 202