131,695 research outputs found
Amplified Sensitivity of Nitrogen-Vacancy Spins in Nanodiamonds using All-Optical Charge Readout
Nanodiamonds containing nitrogen-vacancy (NV) centers offer a versatile
platform for sensing applications spanning from nanomagnetism to in-vivo
monitoring of cellular processes. In many cases, however, weak optical signals
and poor contrast demand long acquisition times that prevent the measurement of
environmental dynamics. Here, we demonstrate the ability to perform fast,
high-contrast optical measurements of charge distributions in ensembles of NV
centers in nanodiamonds and use the technique to improve the spin readout
signal-to-noise ratio through spin-to-charge conversion. A study of 38
nanodiamonds, each hosting 10-15 NV centers with an average diameter of 40 nm,
uncovers complex, multiple-timescale dynamics due to radiative and
non-radiative ionization and recombination processes. Nonetheless, the
nanodiamonds universally exhibit charge-dependent photoluminescence contrasts
and the potential for enhanced spin readout using spin-to-charge conversion. We
use the technique to speed up a relaxometry measurement by a factor of
five.Comment: 13 pages, 14 figure
Eigenvalue-based Cyclostationary Spectrum Sensing Using Multiple Antennas
In this paper, we propose a signal-selective spectrum sensing method for
cognitive radio networks and specifically targeted for receivers with
multiple-antenna capability. This method is used for detecting the presence or
absence of primary users based on the eigenvalues of the cyclic covariance
matrix of received signals. In particular, the cyclic correlation significance
test is used to detect a specific signal-of-interest by exploiting knowledge of
its cyclic frequencies. The analytical threshold for achieving constant false
alarm rate using this detection method is presented, verified through
simulations, and shown to be independent of both the number of samples used and
the noise variance, effectively eliminating the dependence on accurate noise
estimation. The proposed method is also shown, through numerical simulations,
to outperform existing multiple-antenna cyclostationary-based spectrum sensing
algorithms under a quasi-static Rayleigh fading channel, in both spatially
correlated and uncorrelated noise environments. The algorithm also has
significantly lower computational complexity than these other approaches.Comment: 6 pages, 6 figures, accepted to IEEE GLOBECOM 201
Precision spectroscopy with two correlated atoms
We discuss techniques that allow for long coherence times in laser
spectroscopy experiments with two trapped ions. We show that for this purpose
not only entangled ions prepared in decoherence-free subspaces can be used but
also a pair of ions that are not entangled but subject to the same kind of
phase noise. We apply this technique to a measurement of the electric
quadrupole moment of the 3d D5/2 state of 40Ca+ and to a measurement of the
linewidth of an ultrastable laser exciting a pair of 40Ca+ ions
Monitoring Ion Channel Function In Real Time Through Quantum Decoherence
In drug discovery research there is a clear and urgent need for non-invasive
detection of cell membrane ion channel operation with wide-field capability.
Existing techniques are generally invasive, require specialized nano
structures, or are only applicable to certain ion channel species. We show that
quantum nanotechnology has enormous potential to provide a novel solution to
this problem. The nitrogen-vacancy (NV) centre in nano-diamond is currently of
great interest as a novel single atom quantum probe for nanoscale processes.
However, until now, beyond the use of diamond nanocrystals as fluorescence
markers, nothing was known about the quantum behaviour of a NV probe in the
complex room temperature extra-cellular environment. For the first time we
explore in detail the quantum dynamics of a NV probe in proximity to the ion
channel, lipid bilayer and surrounding aqueous environment. Our theoretical
results indicate that real-time detection of ion channel operation at
millisecond resolution is possible by directly monitoring the quantum
decoherence of the NV probe. With the potential to scan and scale-up to an
array-based system this conclusion may have wide ranging implications for
nanoscale biology and drug discovery.Comment: 7 pages, 6 figure
Quantum metrology and its application in biology
Quantum metrology provides a route to overcome practical limits in sensing
devices. It holds particular relevance to biology, where sensitivity and
resolution constraints restrict applications both in fundamental biophysics and
in medicine. Here, we review quantum metrology from this biological context,
focusing on optical techniques due to their particular relevance for biological
imaging, sensing, and stimulation. Our understanding of quantum mechanics has
already enabled important applications in biology, including positron emission
tomography (PET) with entangled photons, magnetic resonance imaging (MRI) using
nuclear magnetic resonance, and bio-magnetic imaging with superconducting
quantum interference devices (SQUIDs). In quantum metrology an even greater
range of applications arise from the ability to not just understand, but to
engineer, coherence and correlations at the quantum level. In the past few
years, quite dramatic progress has been seen in applying these ideas into
biological systems. Capabilities that have been demonstrated include enhanced
sensitivity and resolution, immunity to imaging artifacts and technical noise,
and characterization of the biological response to light at the single-photon
level. New quantum measurement techniques offer even greater promise, raising
the prospect for improved multi-photon microscopy and magnetic imaging, among
many other possible applications. Realization of this potential will require
cross-disciplinary input from researchers in both biology and quantum physics.
In this review we seek to communicate the developments of quantum metrology in
a way that is accessible to biologists and biophysicists, while providing
sufficient detail to allow the interested reader to obtain a solid
understanding of the field. We further seek to introduce quantum physicists to
some of the central challenges of optical measurements in biological science.Comment: Submitted review article, comments and suggestions welcom
Correlation of micro and nano–scale defects with WVTR for aluminium oxide barrier coatings for flexible photovoltaic modules
This paper seeks to establish a correlation between surface topographical defects and water vapour transmission rate (WVTR) measured under laboratory conditions for aluminium–oxide (Al2O3) barrier film employed in flexible photovoltaic (PV) modules. Defects in the barrier layers of PV modules causing high WVTR are not well characterised and understood. A WVTR of ~10−1 g/m2/day is sufficient for the most packaging applications, but ≤10−6 g/m2/day is required for the encapsulation of long–life flexible PV modules (Carcia et al., 2010a, 2010b). In this study, surface metrology techniques along with scanning electron microscopy (SEM) were used for a quantitative characterisation of the barrier film defects. The investigation have provided clear evidence for the correlation of surface defect density and the transmission of water vapour through the barrier coating layer. The outcomes would appear to suggest that small numbers of large defects are the dominant factor in determining WVTR for these barrier layers
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