An EEG Signal Recognition Algorithm During Epileptic Seizure Based on Distributed Edge Computing

Epilepsy is one kind of brain diseases, and its sudden unpredictability is the main cause of disability and even death. Thus, it is of great significance to identify electroencephalogram (EEG) during the seizure quickly and accurately. With the rise of cloud computing and edge computing, the interface between local detection and cloud recognition is established, which promotes the development of portable EEG detection and diagnosis. Thus, we construct a framework for identifying EEG signals in epileptic seizure based on cloud-edge computing. The EEG signals are obtained in real time locally, and the horizontal viewable model is established at the edge to enhance the internal correlation of the signals. The Takagi-Sugeno-Kang (TSK) fuzzy system is established to analyze the epileptic signals. In the cloud, the fusion of clinical features and signal features is established to establish a deep learning framework. Through local signal acquisition, edge signal processing and cloud signal recognition, the diagnosis of epilepsy is realized, which can provide a new idea for the real-time diagnosis and feedback of EEG during epileptic seizure

An overview of deep learning techniques for epileptic seizures detection and prediction based on neuroimaging modalities: Methods, challenges, and future works

Epilepsy is a disorder of the brain denoted by frequent seizures. The symptoms of seizure include confusion, abnormal staring, and rapid, sudden, and uncontrollable hand movements. Epileptic seizure detection methods involve neurological exams, blood tests, neuropsychological tests, and neuroimaging modalities. Among these, neuroimaging modalities have received considerable attention from specialist physicians. One method to facilitate the accurate and fast diagnosis of epileptic seizures is to employ computer-aided diagnosis systems (CADS) based on deep learning (DL) and neuroimaging modalities. This paper has studied a comprehensive overview of DL methods employed for epileptic seizures detection and prediction using neuroimaging modalities. First, DLbased CADS for epileptic seizures detection and prediction using neuroimaging modalities are discussed. Also, descriptions of various datasets, preprocessing algorithms, and DL models which have been used for epileptic seizures detection and prediction have been included. Then, research on rehabilitation tools has been presented, which contains brain-computer interface (BCI), cloud computing, internet of things (IoT), hardware implementation of DL techniques on field-programmable gate array (FPGA), etc. In the discussion section, a comparison has been carried out between research on epileptic seizure detection and prediction. The challenges in epileptic seizures detection and prediction using neuroimaging modalities and DL models have been described. In addition, possible directions for future works in this field, specifically for solving challenges in datasets, DL, rehabilitation, and hardware models, have been proposed. The final section is dedicated to the conclusion which summarizes the significant findings of the paper

EMAP: A Cloud-Edge Hybrid Framework for EEG Monitoring and Cross-Correlation Based Real-time Anomaly Prediction

State-of-the-art techniques for detecting, or predicting, neurological disorders (1) focus on predicting each disorder individually, and are (2) computationally expensive, leading to a delay that can potentially render the prediction useless, especially in critical events. Towards this, we present a real-time two-tiered framework called EMAP, which cross-correlates the input with all the EEG signals in our mega-database (a combination of multiple EEG datasets) at the cloud, while tracking the signal in real-time at the edge, to predict the occurrence of a neurological anomaly. Using the proposed framework, we have demonstrated a prediction accuracy of up to 94% for the three different anomalies that we have tested.Comment: Accepted for Publication at the 57th Design Automation Conference (DAC), July 2020, San Francisco, CA, US

Big data in epilepsy: Clinical and research considerations. Report from the Epilepsy Big Data Task Force of the International League Against Epilepsy

Epilepsy is a heterogeneous condition with disparate etiologies and phenotypic and genotypic characteristics. Clinical and research aspects are accordingly varied, ranging from epidemiological to molecular, spanning clinical trials and outcomes, gene and drug discovery, imaging, electroencephalography, pathology, epilepsy surgery, digital technologies, and numerous others. Epilepsy data are collected in the terabytes and petabytes, pushing the limits of current capabilities. Modern computing firepower and advances in machine and deep learning, pioneered in other diseases, open up exciting possibilities for epilepsy too. However, without carefully designed approaches to acquiring, standardizing, curating, and making available such data, there is a risk of failure. Thus, careful construction of relevant ontologies, with intimate stakeholder inputs, provides the requisite scaffolding for more ambitious big data undertakings, such as an epilepsy data commons. In this review, we assess the clinical and research epilepsy landscapes in the big data arena, current challenges, and future directions, and make the case for a systematic approach to epilepsy big data

A Multi-Tier Distributed fog-based Architecture for Early Prediction of Epileptic Seizures

Epilepsy is the fourth most common neurological problem. With 50 million people living with epilepsy worldwide, about one in 26 people will continue experiencing recurring seizures during their lifetime. Epileptic seizures are characterized by uncontrollable movements and can cause loss of awareness. Despite the optimal use of antiepileptic medications, seizures are still difficult to control due to their sudden and unpredictable nature. Such seizures can put the lives of patients and others at risk. For example, seizure attacks while patients are driving could affect their ability to control a vehicle and could result in injuries to the patients as well as others. Notifying patients before the onset of seizures can enable them to avoid risks and minimize accidents, thus, save their lives. Early and accurate prediction of seizures can play a significant role in improving patients’ quality of life and helping doctors to administer medications through providing a historical overview of patient's condition over time. The individual variability and the dynamic disparity in differentiating between the pre-ictal phase (a period before the onset of the seizure) and other seizures phases make the early prediction of seizures a challenging task. Although several research projects have focused on developing a reliable seizure prediction model, numerous challenges still exist and need to be addressed. Most of the existing approaches are not suitable for real-time settings, which requires bio-signals collection and analysis in real-time. Various methods were developed based on the analysis of EEG signals without considering the notification latency and computational cost to support monitoring of multiple patients. Limited approaches were designed based on the analysis of ECG signals. ECG signals can be collected using consumer wearable devices and are suitable for light-weight real-time analysis. Moreover, existing prediction methods were developed based on the analysis of seizure state and ignored the investigation of pre-ictal state. The analysis of the pre-ictal state is essential in the prediction of seizures at an early stage. Therefore, there is a crucial need to design a novel computing model for early prediction of epileptic seizures. This model would greatly assist in improving the patients' quality of lives. This work proposes a multi-tier architecture for early prediction of seizures based on the analysis of two vital signs, namely, Electrocardiography (ECG) and Electroencephalogram (EEG) signals. The proposed architecture comprises of three tiers: (1) sensing at the first tier, (2) lightweight analysis based on ECG signals at the second tier, and (3) deep analysis based on EEG signals at the third tier. The proposed architecture is developed to leverage the potential of fog computing technology at the second tier for a real-time signal analytics and ubiquitous response. The proposed architecture can enable the early prediction of epileptic seizures, reduce the notification latency, and minimize the energy consumption on real-time data transmissions. Moreover, the proposed architecture is designed to allow for both lightweight and extensive analytics, thus make accurate and reliable decisions. The proposed lightweight model is formulated using the analysis of ECG signals to detect the pre-ictal state. The lightweight model utilizes the Least Squares Support Vector Machines (LS-SVM) classifier, while the proposed extensive analytics model analyzes EEG signals and utilizes Deep Belief Network (DBN) to provide an accurate classification of the patient’s state. The performance of the proposed architecture is evaluated in terms of latency minimization and energy consumption in comparison with the cloud. Moreover, the performance of the proposed prediction models is evaluated using three datasets. Various performance metrics were used to investigate the prediction model performance, including: accuracy, sensitivity, specificity, and F1-Measure. The results illustrate the merits of the proposed architecture and show significant improvement in the early prediction of seizures in terms of accuracy, sensitivity, and specificity

Effective electroencephalogram based epileptic seizure detection using support vector machine and statistical moment’s features

Epilepsy is one of the widespread disorders. It is a noncommunicable disease that affects the human nerve system. Seizures are abnormal patterns of behavior in the electricity of the brain which produce symptoms like losing consciousness, attention or convulsions in the whole body. This paper demonstrates an effective electroencephalogram (EEG) based seizure detection method using discrete wavelet transformation (DWT) for signal decomposition to extract features. An automatic channel selection method was proposed by the researcher to select the best channel from 23 channels based on maximum variance value. The records were segmented into a nonoverlapping segment with long 1-S. The support vector machine (SVM) model was used to automatically detect segments that contain seizures, using both frequency and time domain statistical moment features. The experimental result was obtained from 24 patients in CHB-MIT database. The average accuracy is 94.1, sensitivity is 93.5, specificity is 94.6 and the false positive rate average is 0.054