Cancelable ECG Biometrics using Compressive Sensing-Generalized Likelihood Ratio Test

Electrocardiogram (ECG) has been investigated as promising biometrics, but it cannot be canceled and re-used once compromised just like other biometrics. We propose methods to overcome the issue of irrevocability in ECG biometrics without compromising performance. Our proposed cancelable user authentication uses a generalized likelihood ratio test (GLRT) based on a composite hypothesis testing in compressive sensing (CS) domain We also propose a permutation-based revocation method for CS-based cancelable biometrics so that it becomes resilient to record multiplicity attack. In addition, to compensate for inevitable performance degradation due to cancelable schemes, we also propose two performance improvement methods without undermining cancelable schemes: a self-guided ECG filtering and a T-wave shift model in our CS-GLRT. Finally, our proposed methods were evaluated for various cancelable biometrics criteria with the public ECG-ID data (89 subjects). Our cancelable ECG biometric methods yielded up to 93.0% detection probability at 2.0% false alarm ratio (PD*) and 3.8% equal error rate (EER), which are comparable to or even better than non-cancelable baseline with 93.2% PD* and 4.8% EER for challenging single pulse ECG authentication, respectively. Our proposed methods met all cancelable biometrics criteria theoretically or empirically. Our cancelable secure user template with our novel revocation process is practically non-invertible and robust to record multiplicity attack

???????????? ????????? ?????? ?????? ?????? ?????? ?????? ??????

Department of Electrical EngineeringBiometrics such as fingerprint, iris, face, and electrocardiogram (ECG) have been investigated as convenient and powerful security tools that can potentially replace or supplement current possession or knowledge based authentication schemes. Recently, multi-spectral skin photomatrix (MSP) has been newly found as one of the biometrics. Moreover, since the interest of usage and security for wearable devices have been increasing, multi-modal biometrics authentication which is combining more than two modalities such as (iris + face) or (iris + fingerprint) for powerful and convenience authentication is widely proposed. However, one practical drawback of biometrics is irrevocability. Unlike password, biometrics can not be canceled and re-used once compromised since they are not changed forever. There have been several works on cancelable biometrics to overcome this drawback. ECG has been investigated as a promising biometrics, but there are few research on cancelable ECG biometrics. As we aim to study a way for multi-modal biometric scheme for wearable devices that is assumed circumstance under some limitations such as relatively high performance, low computing power, and limited information (not sharing users information to the public), in this study, we proposed a multi-modal biometrics authentication by combining ECG and MSP. For investigating the performances versus level of fusions, Adaboost algorithm was studied as a score level fusion method, and Majority Voting was studied as a decision level fusion method. Due to ECG signal is 1 dimensional, it provides benefits in wearable devices for overcoming the computing memory limitation. The reasons that we select MSP combination with ECG are it can be collected by measuring on inner-wrist of human body and it also can be considered as hardly stolen modality in remote ways. For proposed multi-modal biometrics, We evaluate our methods using collected data by Brain-Computer-Interface lab with 63 subjects. Our Adaboost based pro- posed multi modal biometrics method with performance boost yielded 99.7% detection probability at 0.1% false alarm ratio (PD0.1) and 0.3% equal error rate (EER), which are far better than simply combining by Majority Voting algorithm with 21.5% PD0.1 and 1.6% EER. Note that for training the Adaboost algorithm, we used only 9 people dataset which is assumed as public data and not included for testing data set, against for knowledge limitation as the other constraint. As initial step for user template protection, We proposed a cancelable ECG based user authentication using a composite hypothesis testing in compressive sensing do- main by deriving a generalized likelihood ratio test (GLRT) detector. We also pro- posed two performance boost tricks in compressive sensing domain to compensate for performance degradation due to cancelable schemes: user template guided filtering and T-wave shift model based GLRT detector for random projection domain. To verify our proposed method, we investigated cancelable biometrics criteria for the proposed methods to confirm that the proposed algorithms are indeed cancelable. For proposed cancelable ECG authentication, We evaluated our proposed methods using ECG data with 147 subjects from three public ECG data sets (ECG-ID, MIT- BIH Normal / Arrhythmia). Our proposed cancelable ECG authentication method is practically cancelable by satisfying all cancelable biometrics criteria. Moreover, our proposed method with performance boost tricks achieved 97.1% detection probability at 1% false alarm ratio (PD1) and 1.9% equal error rate (EER), which are even better than non-cancelable baseline with 94.4% PD1 and 3.1% EER for single pulse ECG authentication.ope

An enhanced machine learning-based biometric authentication system using RR- Interval Framed Electrocardiograms

This paper is targeted in the area of biometric data enabled security by using machine learning for the digital health. The traditional authentication systems are vulnerable to the risks of forgetfulness, loss, and theft. Biometric authentication is has been improved and become the part of daily life. The Electrocardiogram (ECG) based authentication method has been introduced as a biometric security system suitable to check the identification for entering a building and this research provides for studying ECG-based biometric authentication techniques to reshape input data by slicing based on the RR-interval. The Overall Performance (OP) as a newly proposed performance measure is the combined performance metric of multiple authentication measures in this study. The performance of the proposed system using a confusion matrix has been evaluated and it has achieved up to 95% accuracy by compact data analysis. The Amang ECG (amgecg) toolbox in MATLAB is applied to the mean square error (MSE) based upper-range control limit (UCL) which directly affects three authentication performance metrics: the number of accepted samples, the accuracy and the OP. Based on this approach, it is found that the OP could be maximized by applying a UCL of 0.0028, which indicates 61 accepted samples within 70 samples and ensures that the proposed authentication system achieves 95% accuracy

Wrist vascular biometric recognition using a portable contactless system

Human wrist vein biometric recognition is one of the least used vascular biometric modalities. Nevertheless, it has similar usability and is as safe as the two most common vascular variants in the commercial and research worlds: hand palm vein and finger vein modalities. Besides, the wrist vein variant, with wider veins, provides a clearer and better visualization and definition of the unique vein patterns. In this paper, a novel vein wrist non-contact system has been designed, implemented, and tested. For this purpose, a new contactless database has been collected with the software algorithm TGS-CVBR®. The database, called UC3M-CV1, consists of 1200 near-infrared contactless images of 100 different users, collected in two separate sessions, from the wrists of 50 subjects (25 females and 25 males). Environmental light conditions for the different subjects and sessions have been not controlled: different daytimes and different places (outdoor/indoor). The software algorithm created for the recognition task is PIS-CVBR®. The results obtained by combining these three elements, TGS-CVBR®, PIS-CVBR®, and UC3M-CV1 dataset, are compared using two other different wrist contact databases, PUT and UC3M (best value of Equal Error Rate (EER) = 0.08%), taken into account and measured the computing time, demonstrating the viability of obtaining a contactless real-time-processing wrist system.Publicad

Biopotential signals and their applicability to cibersecurity problems

Biometric systems are an uprising technique of identification in today’s world. Many different biometric systems have been used in everyone’s daily life in the past years, such as fingerprint, face scan, ECG, and others. More than 20 years evince that the Elektrokardiogramm (EKG) or Electrocardiogram (ECG) is a feasible method to perform user identification as each person has their unique and inherent Elektrokardiogramm (EKG). A biometric system is based on something that every human being is and cannot lose or possess as it is an eye, the DNA, palm print, vein patterns, iris, retina, etc. For this reason, during the last decade, biometric identification or authentication has gained ground between the classic authentication systems as it was a PIN or a physical key. All biometric systems, to be accepted, must fulfill a set of requirements including universality, uniqueness, permanence, and collectability. The EKG is a biometric trait that not only fulfills those requirements but also has some advantages over other biometric traits. To use an EKG as the biometric trait for identification is motivated by four key points: 1) the collection of an EKG is a non-invasive technique so may contribute to the acceptability among the population; 2) a human being can only be identified if they are alive as their heart must be beating; 3) all living beings have their EKG so it is inclusive; 4) an EKG not only provides identification but also provides a medical and even emotional diagnose. There exist many works regarding user identification with EKGs in the current state-of-the-art. Biometric identification with EKGs has been deployed using many different techniques. Some works use the fiducial points of the EKG signal (T-peak, R-peak, P-onset, QRS-offset, ...) to perform the user identification and others use feature extraction performed by a Neural Network as the classification or identification method. As the EKG is a signal which is expressed in time and frequency, many different Neural Network models can exploit the dissimilarity between each EKG signal from each user to perform user identification such as Recurrent Neural Networks, Convolutional Neural Networks, Long-Short Term Memory, Principal Component Analysis, among others offering very competitive results. Focusing on user identification, depending on the user condition in each case, as has been commented before, the EKG not only contributes as an identification method but also offers a diagnosis as it is a person’s condition from a medical point of view or a person’s status regarding their emotional state. Some research has studied certain conditions such as anxiety over EKG identification showing that higher heart rates might be more complex to identify individuals. Nevertheless, there are some drawbacks in the current state-of-the-art regarding identification with EKG. Many systems use very complexly Deep Learning architectures or, as commented, extract the features by a fiducial analysis making the biometric system too complex and computationally costly. One important flaw, not only in biometric systems but in science, is the lack of publicly available datasets and the use of private ones to perform different studies. Using a private database for any research makes the experiments and results irreproducible and it could be considered a drawback in any science field. Furthermore, many of these works use the EKG signal in a sense that it can be recovered from the identification system so there is no privacy protection for the user as anyone could retrieve their EKG signal. Owing to the many drawbacks of a biometric system based on ECG signals, ELEKTRA is presented in this thesis as a new identification system whose aim is to overcome all the inconveniences of the current proposals. ELEKTRA is a biometric system that performs user identification by using EKGs converted into a heatmap of a set of aligned R-peaks (heartbeats), forming a matrix called an Elektrokardiomatrix (EKM). ELEKTRA is based on past work where the EKM was already created for medical purposes. As far as the literature covers up to this date, all the existing research regarding the use of the EKM is focused on the diagnosis of different Cardiovascular Disease (CVD) such as Congestive Heart Failure, Atrial Fibrillation, and Heart Rate Variability, among others. Therefore, the work presented in this thesis, presumably, is the first one to use the EKM as a valid identification method. In aim to offer reproducible results, four different public databases are taken to show the model feasibility and adaptability: i) the Normal Sinus Rhythm Database (NSRDB), ii) the MIT-BIH Arrhythmia Database (MITBIHDB), iii) the Physikalisch-Technische Bundesanstalt (PTBDB), and iv) the Glasgow University Database (GUDB). The first three of them (i, ii and iii) are taken from Physionet a freely-available repository with medical research data, managed by the MIT Laboratory. However, the fourth database (iv ) is also freely available by petition to Glasgow University. Furthermore, to test ELEKTRA’s adaptability and feasibility of the biometric system presented, four different datasets are built from the databases where the EKG signals are segmented into windows to create several Elektrokardiomatrix (EKM)s. The number of EKMs built for each dataset will depend on the length of the records. For example, for the Normal Sinus Rhythm Database (NSRDB) as the EKG records are very extensive, 3000 EKMs or images per user will be obtained. However, for the three other databases, the highest possible number of EKM images is obtained until the signal is lost. It is important to take into account that depending on the number of heartbeats taken to be represented in each EKM, a different number of EKMs is obtained for the three databases in which EKG recordings are shorter. As higher the number of heartbeats o R-peaks taken (i.e., 7bpf), the fewer images will be obtained. Once the datasets of EKMs are constructed, a simple yet effective Convolutional Neural Network (CNN) is built by one 2D Convolution with ReLU activation, a max-pooling operation followed by a dropout to include regularisation and, and finally, a layer with flattened and dense operations with a softmax or sigmoid function depending if the classification task is categorical o binary to achieve the final classification. With this simple CNN, the feasibility and adaptability of ELEKTRA are demonstrated during all the experiments. The four databases are tested during chapters 3, 4, and 5 where the experimentation takes place. In Chapter 3, the NSRDB is studied as the baseline of identification with control users. Different experiments are conducted with aim of studying ELEKTRA’s behavior. In the first experiments, how many heartbeats are needed to identify a user and the costs of convergence of the model depending on the time computing and the number of heartbeats taken to be represented in the EKM are studied. In this case, similar results are achieved in all the experiments as results close to 100% of accuracy are obtained. In the classification of a non-seen user a user, from a different database that has not been seen in any other experiment, is processed and tested against the network. The result obtained is that a non-seen user or an impersonator would only bypass the system one in ten times which can be considered a low ratio when many systems are blocked after three to five attempts. The classification of a user is tested to have a closer situation in which a low-cost sensor is used. For this experiment, an EKG signal is modified by adding Gaussian noise and then processed as any other signal. As a demonstration of our robust system, an accuracy of 99% is obtained indicating that a noisy signal can be processed too. The last experiment over the NSRDB is where this database is used to test the feasibility of ELEKTRA by testing how many images or EKM are enough to identify a user. Even though there is a decrease in accuracy when the number of images used to train the network is decreased too, a 97% of accuracy is obtained when training the network with only 300 EKMs per user. This chapter concludes that, as shown in all the experiments, ELEKTRA is a valid and feasible identification method for control users. The MIT-BIH Arrhythmia Database (MIT-BIHDB) is a database comprising patients with Arrhythmia and random users, and the Physikalisch- Technische Bundesanstalt (PTBDB) comprises patients with different CVD together with healthy users. Hence, the main goal in Chapter 4 is to study the identification system proposed over users with CVD showing ELEKTRA’s adaptability. First of all, the MIT-BIHDB is tested achieving outperforming results and showing how ELEKTRokardiomatrix Application to biometric identification with Convolutional Neural Networks (ELEKTRA) is capable to identify a pool of users with and without arrhythmia with just a slight decrease of the network’s accuracy as a 97% of accuracy is obtained. Secondly, the whole PTBDB is taken to test the biometric system. The result obtained in this experiment is lower than in the other ones (a 93% of accuracy) as the number of images used to train the network has suffered a great decrease compared to the other experiments and 232 users are being studied. Lastly, ELEKTRA has tested over 162 users from the PTBDB with specific CVD which, namely, are Bundle branch block, Cardiomyopathy, Dysrhythmia, Myocardial infarction, Myocarditis, and Valvular heart disease. Through this experiment, the aim is to see ELEKTRA’s behaviour when only users with CVD are included. Better results are obtained compared to the last experiment. It can be owed that the number of users has decreased and that a CVD makes more unique each EKG as many researchers use the EKM for diagnosis purposes. The conclusion extracted from all the experiments from this chapter is that ELEKTRA is capable to identify users with and without CVD approaching a real-life scenario. In Chapter 5 the Glasgow University Database (GUDB) is tested to evaluate the performance of user identification when the users are performing different activities. The GUDB comprises 25 users performing five different activities with different levels of cardiovascular effort: sitting, walking on a treadmill, doing a maths exam, using a handbike, and running on a treadmill. The proposed biometric system is tested with each of these activities for 3 and 5 bpf achieving different results in each case. For the experiments performed where an activity requiring lower cardiovascular effort such as sitting or walking, the accuracy obtained is close to 100% as it is 99.19% for sitting and 98.59% for walking. Then for the scenarios where higher heartbeat rates are supposed the experiment results in lower accuracies as it is jogging with an 82.63% and biking with a 95.51%. For the maths scenario, its outcome is different; the heartbeat rate for each user could be different depending on how nervous each user is. Hence, a 94.0% is obtained with this activity. The conclusion extracted from these first experiments is that it is more complex to identify users when they are performing an activity that requires a higher cardiovascular effort and, consequently have a higher heart rate. For the following experiment, all scenarios have been merged to study the behaviour of a system that has been trained with users performing different activities. In this case, the results obtained seemed to be close to the mean of the results obtained before as the general accuracy for all the scenarios with 3bpf is 91.32%. For the subsequent experiments, some of the scenarios have been merged into two different categories. On the one hand, the more calmed activities (sitting and walking) have been merged in the so-called Low Cardiovascular Activity (LCA) scenario. The accuracy obtained by training and testing with these two activities together is 97.74% and an EER of 1.01%. On the other hand, the High Cardiovascular Activity (HCA) scenario is composed by activities that require a higher cardiovascular effort (jogging and biking). In this case, the results obtained have decreased compared to the last ones as the accuracy is 85.71%. It can be noticed that what has suffered a considerable increase is the False Rejection Rate (FRR) which is 14.17% without implying an increase in the False Acceptance Rate (FAR) which is still very low as it is 0.6%. The last experiments have been called fight of scenarios as there is a confrontation between scenarios by merging some of them and training with some activities or scenarios and predicting with different ones. The first experiments that can be found in this section are training with the LCA group and testing with the HCA group and vice versa. The results here show a great decrease in the performance as accuracies are 37.24% and 46.42%, respectively. This fact implies that it is more complex to identify users that have been registered with a different heartbeat rate. Last but not least, there are a set of experiments where the activities have been confronted such as training the network with the sitting scenario and testing with the jogging scenario. These experiments confirm the hypothesis for higher heart rates, are more complex to identify users, and even more when the network has been trained over calmed users. Even though, one of the main advantages of the presented model is that, even for low accuracies, the False Acceptance Rate has not increased compared to the other experiments meaning that an impostor could not achieve bypassing the system. Lastly, in Chapter 6 conclusions and discussions are offered. A comparison between ELEKTRA and other biometric systems based on EKGs from the current state-of-the-art is offered. These researches from the literature are examined to show how ELEKTRA outperforms all of them in regards to some of the aspects such as efficiency, complexity, accuracy, error rates, and reproducibility among others. It is important to remark that, compared to the other works, in all experiments performed in this doctoral thesis, really high performances with high accuracies and low error rates are achieved. In fact, what is remarkable is that this performance is obtained using a very simple CNN conformed by just one convolutional layer. By achieving outstanding results with a simple neural network, the solidity of ELEKTRA is proven. By this, ELEKTRA contributes to the state-of-the-art by providing a new method for user identification with EKGs with many benefits. Outstanding results in terms of high accuracy and low error rates in the experiments assure the efficiency of ELEKTRA. The fact that the databases used to perform the experimentation in this doctoral thesis are publicly available, makes this work reproducible in contrast to many other works in the literature. In fact, as the databases used are different depending on the users’ nature conforming to each database, it is established that the identification method proposed is inclusive as all living beings have their own EKG and high accuracies are also obtained when testing the model over users with different CVD. Moreover, as it has been proven that users with CVD can also be identified without having major drawbacks, ELEKTRA offers an identification system that can also offer a diagnosis of the user who is being identified in terms of their medical health. In addition, thanks to the GUDB, ELEKTRA can determine for the first time, as far as the literature reaches, that performing user identification with EKGs over users performing activities requiring a higher cardiovascular effort and consequently having higher heartbeat rates, is more complex. In conclusion, by the studies and experiments performed in this doctoral thesis, it can be assumed that ELEKTRA is a feasible and efficient identification method for biometrics with EKG and outperforms the current stateof- the-art proposals in user identification with EKG.Los sistemas biométricos son una técnica de identificación en auge en la actualidad. En los últimos años se han utilizado muchos sistemas diferentes en la vida cotidiana, como la huella dactilar, el escáner facial, o el ECG, entre otros. De hecho, son más de 20 años los que avalan que el Elektrokardiogramm (EKG) o el Electrocardiogram (ECG) es un método fiable para realizar identificación de usuarios. En esta tesis se propone un nuevo método de identificación biométrica denominado ELEKTRA. Por otro lado, existen algunos inconvenientes en el estado del arte actual respecto a la identificación con EKG. Muchos sistemas utilizan arquitecturas muy complejas de Deep Learning o extraen las características importantes mediante un análisis fiduciario, haciendo que el sistema biométrico sea demasiado complejo o costoso. Un fallo importante, no solo en los sistemas biométricos, es la falta de bases de datos públicas y el uso de bases de datos privadas para la investigación. El uso de bases de datos privadas en cualquier estudio hace que los experimentos y los resultados sean irreproducibles y son un inconveniente en cualquier campo de la ciencia. En esta tesis doctoral se ha desarrollado ELEKTRA, un sistema de identificación biométrica, mediante el uso de imagénes llamadas Elektrokardiomatrix (EKM). Estas imágenes se construyen a partir de realizar un mapa de calor de un conjunto de picos R (latidos) alineados, formando una matriz. Con el fin de ofrecer resultados reproducibles, se usan cuatro diferentes bases de datos públicas para demostrar la viabilidad y adaptabilidad del modelo: la Normal Sinus Rhythm Database (NSRDB), la MIT-BIH Arrhythmia Database (MIT-BIHDB), la Physikalisch-Technische Bundesanstalt (PTBDB) y la Glasgow University Database (GUDB). Se han creado nuevas sub-bases de datos de EKMs a partir de cada una de las bases de datos mencionadas. Además, para testear la adaptabilidad y viabilidad de ELEKTRA como sistema biométrico se construye una CNN sencilla, pero eficaz, con una sola capa Convolucional. Las cuatro bases de datos anteriormente mencionadas se han testeado en los Capítulos 3, 4 y 5. En el Capítulo 3 se estudia la NSRDB como prueba de concepto de identificación en usuarios control. Se realizan diferentes experimentos con el objetivo de estudiar el comportamiento de ELEKTRA. Las características estudiadas con esta base de datos son: cuántos latidos son necesarios para identificar a un usuario; los costes de convergencia del modelo presentado; la clasificación de un usuario jamás visto proveniente de una base de datos diferente; la clasificación de un usuario cuya señal EKG ha sido modificada añadiendo ruido Gaussiano; y la viabilidad de ELEKTRA probando cuántas imágenes o EKM son suficientes para identificar a un usuario. En cuanto a las bases de datos que contienen usuarios con CVD, la MITBIHDB contiene pacientes con Arritmia y usuarios sanos, y la PTBDB contiene pacientes con diferentes CVD junto a usuarios sanos. Estas dos bases de datos se estudian en el Capítulo 4, donde se estudia la adaptabilidad de ELEKTRA a distintas CVDs. En primer lugar, se testea la MIT-BIHDB logrando resultados prometedores y mostrando cómo ELEKTRA es capaz de identificar usuarios con y sin arritmia en el mismo grupo. En segundo lugar, se toma la PTBDB completa obteniendo porcentajes altos de acierto y bajos en cuanto a tasas de error concierne. Y por último, se prueba ELEKTRA sobre algunos usuarios con CVD específicos de la PTBDB para ver su comportamiento cuando sólo se incluyen usuarios con CVD. El resultado de estos experimentos muestra cómo ELEKTRA es capaz de identificar a los usuarios con y sin CVD acercándose a un escenario real. Por último, en el capítulo 5 se prueba ELEKTRA sobre la GUDB para evaluar el rendimiento de la identificación de usuarios cuando éstos realizan diferentes actividades cardiovasculares. La GUDB consta de 25 usuarios que realizan cinco actividades diferentes con distintos niveles de esfuerzo cardiovascular (sentarse, caminar, hacer un examen de matemáticas, usar una bicicleta de mano y correr en una cinta). El sistema biométrico propuesto se prueba con cada una de estas actividades para mostrar que es más complejo identificar a los usuarios cuando realizan una actividad que requiere un mayor esfuerzo cardiovascular y, en consecuencia, tienen una mayor frecuencia cardíaca. Los experimentos realizados consisten en fusionar diferentes actividades para estudiar las diferencias entre las frecuencias cardíacas y cómo la identificación del usuario está relacionada la misma. El experimento más representativo se realiza entrenando el modelo con el escenario en el que el usuario está sentado y realizando la clasificación ciega de usuarios del escenario en el cual están corriendo. En este experimento, se obtiene una precisión realmente baja demostrando que para frecuencias de latidos más altas es más complejo identificar a un usuario. De hecho, una de las principales ventajas del modelo presentado es que, incluso con una precisión baja, la Tasa de Falsa Aceptación no ha aumentado en comparación con los otros experimentos, lo que significa que un impostor no podría conseguir eludir el sistema. Sin embargo, si la base de datos se lanza sobre todas las actividades fusionadas, se muestran resultados precisos que ofrecen un modelo inclusivo para entrenar y probar sobre usuarios que realizan diferentes actividades. De este modo, ELEKTRA contribuye al estado del arte proporcionando un nuevo método de identificac

Biometric Systems

Because of the accelerating progress in biometrics research and the latest nation-state threats to security, this book's publication is not only timely but also much needed. This volume contains seventeen peer-reviewed chapters reporting the state of the art in biometrics research: security issues, signature verification, fingerprint identification, wrist vascular biometrics, ear detection, face detection and identification (including a new survey of face recognition), person re-identification, electrocardiogram (ECT) recognition, and several multi-modal systems. This book will be a valuable resource for graduate students, engineers, and researchers interested in understanding and investigating this important field of study

Learning EEG Biometrics for Person Identification and Authentication

EEG provides appealing biometrics by presenting some unique attributes, not possessed by common biometric modalities like fingerprints, retina and face scan, in terms of robustness against forgery, secrecy and privacy compliance, aliveness detection and potential of continuous authentication. Meanwhile, the use of EEG to provide cognitive indicators for human workload, fatigue and emotions has created an environment where EEG is well-integrated into systems, making it readily available for biometrics purposes. Yet, still, many challenges need to be properly addressed before any actual deployment of EEG-based biometric systems in real-life scenarios: 1) subjects' inconvenience during the signal acquisition process, 2) the relatively low recognition rates, and 3) the lack of robustness against diverse human states. To address the aforementioned issues, this thesis is devoted to learn biometric traits from EEG signals for stable person identification and authentication. State of the art studies of EEG biometrics are mainly divided into two categories, the event-related potential (ERP) category, which relies on a tight control of the cognitive states of the subjects, and the ongoing EEG category, which uses continuous EEG signals (mainly in resting state) naturally produced by the brain without any particular sensory stimulation. Studies in the ERP category focus more on the design of proper signal elicitation protocols or paradigms which usually require repetitive sensory stimulation. Ongoing EEG, on the contrary, is more flexible in terms of signal acquisition, but needs more advanced computational methods for feature extraction and classification. This study focuses on EEG biometrics using ongoing signals in diverse states. Such a flexible system could lead to an effective deployment in the real world. Specifically, this work focuses on ongoing EEG signals under diverse human states without strict task-specific controls in terms of brain response elicitation during signal acquisition. This is in contrast to previous studies that rely on specific sensory stimulation and synthetic cognitive tasks to tightly control the cognitive state of the subject being reflected in the resulting EEG activity, or to use resting state EEG signals. The relaxation of the reliance of the user's cognitive state makes the signal acquisition process streamlined, which in turn facilitates the actual deployment of the EEG biometrics system. Furthermore, not relying on sensory stimulation and cognitive tasks also allows for flexible and unobtrusive biometric systems that work in the background without interrupting the users, which is especially important in continuous scenarios. However, relaxing the system's reliance on the human state also means losing control of the EEG activity produced. As a result, EEG signals captured from the scalp may be contaminated by the active involvement of the tasks and cognitive states such as workload and emotion. Therefore, it becomes a challenge to learn identity-bearing information from the complicated signals to support high stability EEG biometrics. Possible solutions are proposed and investigated from two main perspectives, feature extraction and pattern classification. Specifically, graph features and learning models are proposed based on the brain connectivity, graph theory, and deep learning algorithms. A comprehensive investigation is conducted to assess the performance of proposed methods and existing methods in biometric identification and authentication, including in continuous scenarios. The methods and experiments are reported and detailed in the corresponding chapters, with the results obtained from data analysis

Machine Learning for Biomedical Application

Biomedicine is a multidisciplinary branch of medical science that consists of many scientific disciplines, e.g., biology, biotechnology, bioinformatics, and genetics; moreover, it covers various medical specialties. In recent years, this field of science has developed rapidly. This means that a large amount of data has been generated, due to (among other reasons) the processing, analysis, and recognition of a wide range of biomedical signals and images obtained through increasingly advanced medical imaging devices. The analysis of these data requires the use of advanced IT methods, which include those related to the use of artificial intelligence, and in particular machine learning. It is a summary of the Special Issue “Machine Learning for Biomedical Application”, briefly outlining selected applications of machine learning in the processing, analysis, and recognition of biomedical data, mostly regarding biosignals and medical images