Inference with Constrained Hidden Markov Models in PRISM

A Hidden Markov Model (HMM) is a common statistical model which is widely used for analysis of biological sequence data and other sequential phenomena. In the present paper we show how HMMs can be extended with side-constraints and present constraint solving techniques for efficient inference. Defining HMMs with side-constraints in Constraint Logic Programming have advantages in terms of more compact expression and pruning opportunities during inference. We present a PRISM-based framework for extending HMMs with side-constraints and show how well-known constraints such as cardinality and all different are integrated. We experimentally validate our approach on the biologically motivated problem of global pairwise alignment

The PITA System: Tabling and Answer Subsumption for Reasoning under Uncertainty

Many real world domains require the representation of a measure of uncertainty. The most common such representation is probability, and the combination of probability with logic programs has given rise to the field of Probabilistic Logic Programming (PLP), leading to languages such as the Independent Choice Logic, Logic Programs with Annotated Disjunctions (LPADs), Problog, PRISM and others. These languages share a similar distribution semantics, and methods have been devised to translate programs between these languages. The complexity of computing the probability of queries to these general PLP programs is very high due to the need to combine the probabilities of explanations that may not be exclusive. As one alternative, the PRISM system reduces the complexity of query answering by restricting the form of programs it can evaluate. As an entirely different alternative, Possibilistic Logic Programs adopt a simpler metric of uncertainty than probability. Each of these approaches -- general PLP, restricted PLP, and Possibilistic Logic Programming -- can be useful in different domains depending on the form of uncertainty to be represented, on the form of programs needed to model problems, and on the scale of the problems to be solved. In this paper, we show how the PITA system, which originally supported the general PLP language of LPADs, can also efficiently support restricted PLP and Possibilistic Logic Programs. PITA relies on tabling with answer subsumption and consists of a transformation along with an API for library functions that interface with answer subsumption

On the Implementation of the Probabilistic Logic Programming Language ProbLog

The past few years have seen a surge of interest in the field of probabilistic logic learning and statistical relational learning. In this endeavor, many probabilistic logics have been developed. ProbLog is a recent probabilistic extension of Prolog motivated by the mining of large biological networks. In ProbLog, facts can be labeled with probabilities. These facts are treated as mutually independent random variables that indicate whether these facts belong to a randomly sampled program. Different kinds of queries can be posed to ProbLog programs. We introduce algorithms that allow the efficient execution of these queries, discuss their implementation on top of the YAP-Prolog system, and evaluate their performance in the context of large networks of biological entities.Comment: 28 pages; To appear in Theory and Practice of Logic Programming (TPLP

On the Implementation of the Probabilistic Logic Programming Language ProbLog

The past few years have seen a surge of interest in the field of probabilistic logic learning and statistical relational learning. In this endeavor, many probabilistic logics have been developed. ProbLog is a recent probabilistic extension of Prolog motivated by the mining of large biological networks. In ProbLog, facts can be labeled with probabilities. These facts are treated as mutually independent random variables that indicate whether these facts belong to a randomly sampled program. Different kinds of queries can be posed to ProbLog programs. We introduce algorithms that allow the efficient execution of these queries, discuss their implementation on top of the YAP-Prolog system, and evaluate their performance in the context of large networks of biological entities