An Optimization Based Design Framework for Multi-Functional 3D Printing

This work investigates design analysis and optimization methods for the integration of active internal systems into a component for manufacture using multi-material 3D printing processes. This enables efficient design of optimal multifunctional components that exploit the design freedoms of additive manufacturing (AM). The main contributions of this paper are in two areas: 1) the automated placement and routing of electrical systems within the component volume and, 2) the accommodation of the effect of this system integration on the structural response of the part through structural topology optimization (TO). A novel voxel modeling approach was used to facilitate design flexibility and to allow direct mapping to the 3D printer jetting nozzles.Mechanical Engineerin

Towards negative cycle canceling in wind farm cable layout optimization

Abstract In the Wind Farm Cabling Problem (WCP) the task is to design the internal cabling of a wind farm such that all power from the turbines can be transmitted to the substations and the costs for the cabling are minimized. Cables can be chosen from several available cable types, each of which has a thermal capacity and cost. Until now, solution approaches mainly use Mixed-integer Linear Programs (MILP) or metaheuristics. We present our current state of research on a fast heuristic specifically designed for WCP. We introduce an algorithm that iteratively improves a cable layout by finding and canceling negative cycles in a suitably defined network. Our simulations on publicly available benchmark sets show that the heuristic is not only fast but it tends to produce good results. Currently our algorithm gives better solutions on large wind farms compared to an MILP solver. However, on small to medium instances the solver performs better in terms of solution quality, which represents a starting point for future work

Multi-level evolutionary algorithms resource allocation utilizing model-based systems engineering

This research presents an innovative approach to solve the resource allocation problems using Multi-level Evolutionary Algorithms. Evolutionary Algorithms are used to solve resource allocation problems in different domains and their results are then incorporated into a higher level system solution using another Evolutionary Algorithm to solve base camp planning problems currently faced by the U.S. Department of Defense. Two models are introduced to solve two domain specific models: a logistics model and a power model. The logistic model evaluates routes for logistics vehicles on a daily basis with a goal of reducing fuel usage by delivery trucks. The evaluation includes distance traveled and other constraints such as available resource levels and priority of refilling. The Power model incorporates an open source electrical distribution simulator to evaluate the placement of structures and generators on a map to reduce fuel usage. These models are used as the fitness function for two separate Evolutionary Algorithms to find solutions that reduce fuel consumption within the individual domains. A multi-level Evolutionary Algorithm is then presented, where the two Evolutionary Algorithms share information with a higher level Evolutionary Algorithm that combines the results to account for problem complexity from the interfacing of these systems. The results of using these methods on 5 different base camp sizes show that the techniques provide a considerable reduction of fuel consumption. While the Evolutionary Algorithms show significant improvement over the current methods, the multi-level Evolutionary Algorithm shows better performance than using individual Evolutionary Algorithms, with the results showing a 19.25 % decrease in fuel consumption using the multi-level Evolutionary Algorithm --Abstract, page iii

Design, development and application of an automated framework for cell growth and laboratory evolution

Precise control over microbial cell growth conditions could enable detection of minute phenotypic changes, which would improve our understanding of how genotypes are shaped by adaptive selection. Although automated cell- culture systems such as bioreactors offer strict control over liquid culture conditions, they often do not scale to high-throughput or require cumbersome redesign to alter growth conditions. I report the design and validation of eVOLVER, a scalable DIY framework that can be configured to carry out high- throughput growth experiments in molecular evolution, systems biology, and microbiology. I perform high-throughput evolution of yeast across systematically varied population density niches to show how eVOLVER can precisely characterize adaptive niches. I describe growth selection using time-varying temperature programs on a genome-wide yeast knockout library to identify strains with altered sensitivity to changes in temperature magnitude or frequency. Inspired by large-scale integration of electronics and microfluidics, I also demonstrate millifluidic multiplexing modules that enable multiplexed media routing, cleaning, vial-to-vial transfers and automated yeast mating

Applications of the Internet of Things and optimization to inventory and distribution management

This thesis is part of the IoFEED (EU funded) project, which aims to monitor approximately 325 farm bins and investigates business processes carried out between farmers and animal feed producers. We propose a computer-aided system to control and optimize the supply chain to deliver animal feed to livestock farms. Orders can be of multiple types of feed, shipped from multiple depots using a fleet of heterogeneous vehicles with multiple compartments. Additionally, this case considers some business-specific constraints, such as product compatibility, facility accessibility restrictions, prioritized locations, or bio-security constraints. A digital twin based approach is implemented at the farm level by installing sensors to remotely measure the inventories. This thesis also embraces these sensors' design and manufacturing process, seeking the required precision and easy deployability at scale. Our approach combines biased-randomization techniques with a simheuristic framework to make use of data provided by the sensors. The analysis of results is based on these two real pilots, and showcases the insights obtained during the IoFEED project. The results of this thesis show how the Internet of Things and simulation-based optimization methods combine successfully to optimize deliveries of feed to livestock farms.Esta tesis forma parte del proyecto IoFeeD, financiado por la Unión Europea, que tiene como objetivo monitorizar remotamente el stock de 325 contenedores agrícolas e investigar los procesos comerciales llevados a cabo entre agricultores y productores de pienso. Proponemos un sistema de ayuda a la toma de decisiones para controlar y optimizar la cadena de suministro de pienso en las explotaciones ganaderas. Los pedidos pueden ser de varios tipos de pienso y pueden enviarse desde varios centros de fabricación mediante el uso de una flota de vehículos heterogéneos con varios compartimentos. Además, se tienen en cuenta algunas restricciones específicas de la empresa, como, por ejemplo, la compatibilidad del producto, las restricciones de accesibilidad en las instalaciones, las ubicaciones priorizadas o las restricciones de bioseguridad. A escala de granja, se implementa un enfoque basado en gemelos digitales mediante la instalación de sensores para medir los inventarios de forma remota. En el marco de esta tesis, se desarrollan estos sensores buscando la precisión requerida, así como las características oportunas que permitan su instalación a gran escala. Nuestro enfoque combina técnicas de aleatorización sesgada con un marco simheurístico para hacer uso de los datos proporcionados por los sensores. El análisis de los resultados se basa en estos dos pilotos reales y muestra las ideas obtenidas durante el proyecto IoFeeD. Los resultados de esta tesis muestran cómo la internet de las cosas y los métodos de optimización basados en simulación se combinan con éxito para optimizar las operaciones de suministro de pienso para el consumo animal en las explotaciones ganaderas.Aquesta tesi forma part del projecte IoFeeD, finançat per la Unió Europea, que té com a objectiu controlar remotament l'estoc de 325 sitges i investigar els processos de negoci duts a terme entre agricultors i productors de pinso. Proposem un sistema d'ajuda a la presa de decisions per controlar i optimitzar la cadena de subministrament de pinso a les explotacions ramaderes. Les comandes poden ser de diversos tipus de pinso i es poden enviar des de diversos centres de fabricació mitjançant l'ús d'una flota de vehicles heterogenis amb diversos compartiments. A més, es tenen en compte algunes restriccions específiques de l'empresa, com ara la compatibilitat del producte, les restriccions d'accessibilitat a les instal·lacions, les ubicacions prioritzades o les restriccions de bioseguretat. A escala de granja, s'implementa un enfocament basat en bessons digitals mitjançant la instal·lació de sensors per mesurar remotament els inventaris. En el marc de la tesi, es desenvolupa aquest sensor cercant la precisió requerida i les característiques oportunes que en permetin la instal·lació a gran escala. El nostre enfocament combina tècniques d'aleatorització esbiaixada amb un marc simheurístic per fer ús de les dades proporcionades pels sensors. L'anàlisi dels resultats es basa en aquests dos pilots reals i mostra les idees obtingudes durant el projecte IoFeeD. Els resultats d'aquesta tesi mostren com la internet de les coses i els mètodes d'optimització basats en simulació es combinen amb èxit per optimitzar les operacions de subministrament de pinso per al consum animal a les explotacions ramaderes.Tecnologies de la informació i de xarxe

The business Challenges In Communicating, Mobile Or Otherwise

This survey paper analyses some of the fundamental economic and management science issues concerning the communications and information economy ,with special emphasis on mobile communications. Are first highlighted major trends such as the balkanisation of the communications networks , and the advent of competitive tariffs. This leads to a move away from time and distance based charges to tariffs covering bandwidth, service , and contents use. It is noted that very few resources have gone into the analysis of that sector and its inter-relations with others. The paper advocates for more visibility and research into the unique aspects of the communications and information sector. It does so by making an inventory of key economics ,management, and computational economics research issues in need of contributions, selected from the following areas: public communications infrastructure and tariffing principles, sales of communications services, public access and equal access policies, competitive access pricing, communications industry finance, engineering-economic studies, information contents and macroeconomic issues. Finally , the specific aspects of models of the communications and media sector are addressed in view of modelling work. This includes variables, pricing and production models for both communications and information contents . The most unique contribution is here a formal model for quantifying and pricing knowledge , both for consumption and for assets building .telecommunications;mobile communications;tariffs;knowledge bases;public access;content