10,140 research outputs found
TRIDEnT: Building Decentralized Incentives for Collaborative Security
Sophisticated mass attacks, especially when exploiting zero-day
vulnerabilities, have the potential to cause destructive damage to
organizations and critical infrastructure. To timely detect and contain such
attacks, collaboration among the defenders is critical. By correlating
real-time detection information (alerts) from multiple sources (collaborative
intrusion detection), defenders can detect attacks and take the appropriate
defensive measures in time. However, although the technical tools to facilitate
collaboration exist, real-world adoption of such collaborative security
mechanisms is still underwhelming. This is largely due to a lack of trust and
participation incentives for companies and organizations. This paper proposes
TRIDEnT, a novel collaborative platform that aims to enable and incentivize
parties to exchange network alert data, thus increasing their overall detection
capabilities. TRIDEnT allows parties that may be in a competitive relationship,
to selectively advertise, sell and acquire security alerts in the form of
(near) real-time peer-to-peer streams. To validate the basic principles behind
TRIDEnT, we present an intuitive game-theoretic model of alert sharing, that is
of independent interest, and show that collaboration is bound to take place
infinitely often. Furthermore, to demonstrate the feasibility of our approach,
we instantiate our design in a decentralized manner using Ethereum smart
contracts and provide a fully functional prototype.Comment: 28 page
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A brief network analysis of Artificial Intelligence publication
In this paper, we present an illustration to the history of Artificial
Intelligence(AI) with a statistical analysis of publish since 1940. We
collected and mined through the IEEE publish data base to analysis the
geological and chronological variance of the activeness of research in AI. The
connections between different institutes are showed. The result shows that the
leading community of AI research are mainly in the USA, China, the Europe and
Japan. The key institutes, authors and the research hotspots are revealed. It
is found that the research institutes in the fields like Data Mining, Computer
Vision, Pattern Recognition and some other fields of Machine Learning are quite
consistent, implying a strong interaction between the community of each field.
It is also showed that the research of Electronic Engineering and Industrial or
Commercial applications are very active in California. Japan is also publishing
a lot of papers in robotics. Due to the limitation of data source, the result
might be overly influenced by the number of published articles, which is to our
best improved by applying network keynode analysis on the research community
instead of merely count the number of publish.Comment: 18 pages, 7 figure
E-infrastructures fostering multi-centre collaborative research into the intensive care management of patients with brain injury
Clinical research is becoming ever more collaborative with multi-centre trials now a common practice. With this in mind, never has it been more important to have secure access to data and, in so doing, tackle the challenges of inter-organisational data access and usage. This is especially the case for research conducted within the brain injury domain due to the complicated multi-trauma nature of the disease with its associated complex collation of time-series data of varying resolution and quality. It is now widely accepted that advances in treatment within this group of patients will only be delivered if the technical infrastructures underpinning the collection and validation of multi-centre research data for clinical trials is improved. In recognition of this need, IT-based multi-centre e-Infrastructures such as the Brain Monitoring with Information Technology group (BrainIT - www.brainit.org) and Cooperative Study on Brain Injury Depolarisations (COSBID - www.cosbid.de) have been formed. A serious impediment to the effective implementation of these networks is access to the know-how and experience needed to install, deploy and manage security-oriented middleware systems that provide secure access to distributed hospital based datasets and especially the linkage of these data sets across sites. The recently funded EU framework VII ICT project Advanced Arterial Hypotension Adverse Event prediction through a Novel Bayesian Neural Network (AVERT-IT) is focused upon tackling these challenges. This chapter describes the problems inherent to data collection within the brain injury medical domain, the current IT-based solutions designed to address these problems and how they perform in practice. We outline how the authors have collaborated towards developing Grid solutions to address the major technical issues. Towards this end we describe a prototype solution which ultimately formed the basis for the AVERT-IT project. We describe the design of the underlying Grid infrastructure for AVERT-IT and how it will be used to produce novel approaches to data collection, data validation and clinical trial design is also presented
Advances in computational modelling for personalised medicine after myocardial infarction
Myocardial infarction (MI) is a leading cause of premature morbidity and mortality worldwide. Determining which patients will experience heart failure and sudden cardiac death after an acute MI is notoriously difficult for clinicians. The extent of heart damage after an acute MI is informed by cardiac imaging, typically using echocardiography or sometimes, cardiac magnetic resonance (CMR). These scans provide complex data sets that are only partially exploited by clinicians in daily practice, implying potential for improved risk assessment. Computational modelling of left ventricular (LV) function can bridge the gap towards personalised medicine using cardiac imaging in patients with post-MI. Several novel biomechanical parameters have theoretical prognostic value and may be useful to reflect the biomechanical effects of novel preventive therapy for adverse remodelling post-MI. These parameters include myocardial contractility (regional and global), stiffness and stress. Further, the parameters can be delineated spatially to correspond with infarct pathology and the remote zone. While these parameters hold promise, there are challenges for translating MI modelling into clinical practice, including model uncertainty, validation and verification, as well as time-efficient processing. More research is needed to (1) simplify imaging with CMR in patients with post-MI, while preserving diagnostic accuracy and patient tolerance (2) to assess and validate novel biomechanical parameters against established prognostic biomarkers, such as LV ejection fraction and infarct size. Accessible software packages with minimal user interaction are also needed. Translating benefits to patients will be achieved through a multidisciplinary approach including clinicians, mathematicians, statisticians and industry partners
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