Flow rate--pressure drop relation for deformable shallow microfluidic channels

Laminar flow in devices fabricated from soft materials causes deformation of the passage geometry, which affects the flow rate--pressure drop relation. For a given pressure drop, in channels with narrow rectangular cross-section, the flow rate varies as the cube of the channel height, so deformation can produce significant quantitative effects, including nonlinear dependence on the pressure drop [{Gervais, T., El-Ali, J., G\"unther, A. \& Jensen, K.\ F.}\ 2006 Flow-induced deformation of shallow microfluidic channels.\ \textit{Lab Chip} \textbf{6}, 500--507]. Gervais et. al. proposed a successful model of the deformation-induced change in the flow rate by heuristically coupling a Hookean elastic response with the lubrication approximation for Stokes flow. However, their model contains a fitting parameter that must be found for each channel shape by performing an experiment. We present a perturbation approach for the flow rate--pressure drop relation in a shallow deformable microchannel using the theory of isotropic quasi-static plate bending and the Stokes equations under a lubrication approximation (specifically, the ratio of the channel's height to its width and of the channel's height to its length are both assumed small). Our result contains no free parameters and confirms Gervais et. al.'s observation that the flow rate is a quartic polynomial of the pressure drop. The derived flow rate--pressure drop relation compares favorably with experimental measurements.Comment: 20 pages, 6 figures; v2 minor revisions, accepted for publication in the Journal of Fluid Mechanic

Fluid-structure interaction in blood flow capturing non-zero longitudinal structure displacement

We present a new model and a novel loosely coupled partitioned numerical scheme modeling fluid-structure interaction (FSI) in blood flow allowing non-zero longitudinal displacement. Arterial walls are modeled by a {linearly viscoelastic, cylindrical Koiter shell model capturing both radial and longitudinal displacement}. Fluid flow is modeled by the Navier-Stokes equations for an incompressible, viscous fluid. The two are fully coupled via kinematic and dynamic coupling conditions. Our numerical scheme is based on a new modified Lie operator splitting that decouples the fluid and structure sub-problems in a way that leads to a loosely coupled scheme which is {unconditionally} stable. This was achieved by a clever use of the kinematic coupling condition at the fluid and structure sub-problems, leading to an implicit coupling between the fluid and structure velocities. The proposed scheme is a modification of the recently introduced "kinematically coupled scheme" for which the newly proposed modified Lie splitting significantly increases the accuracy. The performance and accuracy of the scheme were studied on a couple of instructive examples including a comparison with a monolithic scheme. It was shown that the accuracy of our scheme was comparable to that of the monolithic scheme, while our scheme retains all the main advantages of partitioned schemes, such as modularity, simple implementation, and low computational costs

The effect of a concentration-dependent viscosity on\ud particle transport in a channel flow with porous walls

We analyse the transport of a dilute suspension of particles through a channel with porous walls accounting for the concentration dependence of the viscosity. Two cases of leakage flow of fluid through the porous channel walls are studied: (i) constant flux, and (ii) dependent on the pressure drop across the wall. The effect of mixing the suspension first compared with point injection is examined by considering inlet concentration distributions of different widths. We find that a pessimal distribution width exists that maximizes the required hydrodynamic pressure for a constant fluid influx. We also show that the presence of an osmotic pressure may lead to fluid being sucked into the channel. We consider how the application of an external hydrodynamic pressure affects this observation and discuss the significance of our results for water filtration

Asymptotic approach to the generalized Brinkman’s equation with pressure dependent viscosity and drag coefficient

In this paper we investigate the fluid flow through a thin (or long) channel filled with a fluid saturated porous medium. We are motivated by some important applications of the porous medium flow in which the viscosity of fluids can change significantly with pressure. In view of that, we consider the generalized Brinkman’s equation which takes into account the exponential dependence of the viscosity and the drag coefficient on the pressure. We propose an approach using the concept of the transformed pressure combined with the asymptotic analysis with respect to the thickness of the channel. As a result, we derive the asymptotic solution in the explicit form and compare it with the solution of the standard Brinkman’s model with constant viscosity. To our knowledge, such analysis cannot be found in the existing literature and, thus, we believe that the provided result could improve the known engineering practice.Croatian Science FoundationFundação de Amparo à Pesquisa do Estado de São PauloConselho Nacional de Desenvolvimento Científico e TecnológicoMinisterio de Economía y CompetitividadJunta de Andalucí