GANs schön kompliziert: Applications of Generative Adversarial Networks

Scientific research progresses via model-building. Researchers attempt to build realistic models of real-world phenomena, ranging from bacterial growth to galactic motion, and study these models as a means of understanding these phenomena. However, making these models as realistic as possible often involves fitting them to experimentally measured data. Recent advances in experimental methods have allowed for the collection of large-scale datasets. Simultaneously, advancements in computational capacity have allowed for more complex model-building. The confluence of these two factors accounts for the rise of machine learning methods as powerful tools, both for building models and fitting these models to large scale datasets. In this thesis, we use a particular machine learning technique: generative adversarial networks (GANs). GANs are a flexible and powerful tool, capable of fitting a wide variety of models. We explore the properties of GANs that underpin this flexibility, and show how we can capitalize on them in different scientific applications, beyond the image- and text-generating applications they are well-known for. Here we present three different applications of GANs. First, we show how GANs can be used as generative models of neural spike trains, and how they are capable of capturing more features of these spike trains compared to other approaches. We also show how this could enable insight into how information about stimuli are encoded in the spike trains. Second, we demonstrate how GANs can be used as density estimators for extending simulation-based Bayesian inference to high-dimensional parameter spaces. In this form, we also show how GANs bridge Bayesian inference methods and variational inference with autoencoders and use them to fit complex climate models to data. Finally, we use GANs to infer synaptic plasticity rules for biological rate networks directly from data. We then show how GANs be used to test the robustness of the inferred rules to differences in data and network initialisation. Overall, we repurpose GANs in new ways for a variety of scientific domains, and show that they confer specific advantages over the state-of-the-art methods in each of these domains

Signal processing and image restoration techniques for two-dimensional eddy current nondestructive evaluation

This dissertation presents a comprehensive study on the forward modeling methods, signal processing techniques, and image restoration techniques for two-dimensional eddy current nondestructive evaluation. The basic physical forward method adopted in this study is the volume integral method. We have applied this model to the eddy current modeling problem for half space geometry and thin plate geometry. To reduce the computational complexity of the volume integral method, we have developed a wavelet expansion method which utilizes the multiresolution compression capability of the wavelet basis to greatly reduce the amount of computation with small loss in accuracy. To further improve the speed of forward modeling, we have developed a fast eddy current model based on a radial basis function neural network. This dissertation also contains investigations on signal processing techniques to enhance flaw signals in two-dimensional eddy current inspection data. The processing procedures developed in this study include a set of preprocessing techniques, a background removal technique based on principal component analysis, and grayscale morphological operations to detect flaw signals. Another important part of the dissertation concerns image restoration techniques which can remove the blurring in impedance change images due to the diffusive nature of the eddy current testing. We have developed two approximate linear image restoration methods--the Wiener filtering method and the maximum entropy method. Both linear restoration methods are based on an approximate linear forward model formulated by using the Born approximation. To improve the quality of restoration, we have also developed nonlinear image restoration methods based on simulated annealing and a genetic algorithm. Those nonlinear methods are based on the neural network forward model which is more accurate than the approximate linear forward model

Biologically inspired feature extraction for rotation and scale tolerant pattern analysis

Biologically motivated information processing has been an important area of scientific research for decades. The central topic addressed in this dissertation is utilization of lateral inhibition and more generally, linear networks with recurrent connectivity along with complex-log conformal mapping in machine based implementations of information encoding, feature extraction and pattern recognition. The reasoning behind and method for spatially uniform implementation of inhibitory/excitatory network model in the framework of non-uniform log-polar transform is presented. For the space invariant connectivity model characterized by Topelitz-Block-Toeplitz matrix, the overall network response is obtained without matrix inverse operations providing the connection matrix generating function is bound by unity. It was shown that for the network with the inter-neuron connection function expandable in a Fourier series in polar angle, the overall network response is steerable. The decorrelating/whitening characteristics of networks with lateral inhibition are used in order to develop space invariant pre-whitening kernels specialized for specific category of input signals. These filters have extremely small memory footprint and are successfully utilized in order to improve performance of adaptive neural whitening algorithms. Finally, the method for feature extraction based on localized Independent Component Analysis (ICA) transform in log-polar domain and aided by previously developed pre-whitening filters is implemented. Since output codes produced by ICA are very sparse, a small number of non-zero coefficients was sufficient to encode input data and obtain reliable pattern recognition performance

Toward a further understanding of object feature binding: a cognitive neuroscience perspective.

The aim of this thesis is to lead to a further understanding of the neural mechanisms underlying object feature binding in the human brain. The focus is on information processing and integration in the visual system and visual shortterm memory. From a review of the literature it is clear that there are three major competing binding theories, however, none of these individually solves the binding problem satisfactorily. Thus the aim of this research is to conduct behavioural experimentation into object feature binding, paying particular attention to visual short-term memory. The behavioural experiment was designed and conducted using a within-subjects delayed responset ask comprising a battery of sixty-four composite objects each with three features and four dimensions in each of three conditions (spatial, temporal and spatio-temporal).Findings from the experiment,which focus on spatial and temporal aspects of object feature binding and feature proximity on binding errors, support the spatial theories on object feature binding, in addition we propose that temporal theories and convergence, through hierarchical feature analysis, are also involved. Because spatial properties have a dedicated processing neural stream, and temporal properties rely on limited capacity memory systems, memories for sequential information would likely be more difficult to accuratelyr ecall. Our study supports other studies which suggest that both spatial and temporal coherence to differing degrees,may be involved in object feature binding. Traditionally, these theories have purported to provide individual solutions, but this thesis proposes a novel unified theory of object feature binding in which hierarchical feature analysis, spatial attention and temporal synchrony each plays a role. It is further proposed that binding takes place in visual short-term memory through concerted and integrated information processing in distributed cortical areas. A cognitive model detailing this integrated proposal is given. Next, the cognitive model is used to inform the design and suggested implementation of a computational model which would be able to test the theory put forward in this thesis. In order to verify the model, future work is needed to implement the computational model.Thus it is argued that this doctoral thesis provides valuable experimental evidence concerning spatio-temporal aspects of the binding problem and as such is an additional building block in the quest for a solution to the object feature binding problem

Toward a further understanding of object feature binding : a cognitive neuroscience perspective

The aim of this thesis is to lead to a further understanding of the neural mechanisms underlying object feature binding in the human brain. The focus is on information processing and integration in the visual system and visual shortterm memory. From a review of the literature it is clear that there are three major competing binding theories, however, none of these individually solves the binding problem satisfactorily. Thus the aim of this research is to conduct behavioural experimentation into object feature binding, paying particular attention to visual short-term memory. The behavioural experiment was designed and conducted using a within-subjects delayed responset ask comprising a battery of sixty-four composite objects each with three features and four dimensions in each of three conditions (spatial, temporal and spatio-temporal).Findings from the experiment,which focus on spatial and temporal aspects of object feature binding and feature proximity on binding errors, support the spatial theories on object feature binding, in addition we propose that temporal theories and convergence, through hierarchical feature analysis, are also involved. Because spatial properties have a dedicated processing neural stream, and temporal properties rely on limited capacity memory systems, memories for sequential information would likely be more difficult to accuratelyr ecall. Our study supports other studies which suggest that both spatial and temporal coherence to differing degrees,may be involved in object feature binding. Traditionally, these theories have purported to provide individual solutions, but this thesis proposes a novel unified theory of object feature binding in which hierarchical feature analysis, spatial attention and temporal synchrony each plays a role. It is further proposed that binding takes place in visual short-term memory through concerted and integrated information processing in distributed cortical areas. A cognitive model detailing this integrated proposal is given. Next, the cognitive model is used to inform the design and suggested implementation of a computational model which would be able to test the theory put forward in this thesis. In order to verify the model, future work is needed to implement the computational model.Thus it is argued that this doctoral thesis provides valuable experimental evidence concerning spatio-temporal aspects of the binding problem and as such is an additional building block in the quest for a solution to the object feature binding problem.EThOS - Electronic Theses Online ServiceGBUnited Kingdo