10 research outputs found
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Influences of the use of management systems on the moral attitudes and behaviours of small and medium sized enterprises : measuring the dynamic interplay of morality, environment and managing systems
The author designs a comprehensive model to characterise and optimise sustainable performance of small and medium sized enterprises SMEs - in the overall context of physical environment, society, economy and business. This model embraces issues of morality, management system, and environment and uses a corresponding measurement tool to discuss the interplay of these issues with the intention of leading SMEs to continuous improvement. For the design, issues of system thinking have been applied to cope with the complexity of the interplay of the elements.
The model and the measurement tool are tested by a longitudinal survey of 27 SMEs in Switzerland and Germany. An outstanding issue of this survey is the interviewing of people from different hierarchical levels and departments of the companies (total: 212 individuals); it provides a comprehensive view of companies' attitudes and behaviours. The survey illustrates that a standardised management system is not decisive for the implementation of an increasingly dynamic and circular system with intensive integration of people. The implementation merely depends on the (moral) attitudes and behaviours of owners or top managers and employees. But SMEs with standardised (especially environmental) management systems generally demonstrate more outcomes towards embedded morality, circularity and integration as well as effectiveness and sustainable performance.
Through the design and development of a comprehensive SME model and measuring tool, the author broadens the gap of narrowing SME research concerning optimised performance on individual issues and positions of individual companies to an overall context of society, economy, business and physical environment
10 Years Barometer for Public Real Estate in the Netherlands
2007, the Ministry of Housing and Spatial Planning took the initiative to issue the social building blocks: real estate for facilities. This has been the first attempt to deal with social real estate professionally as an asset. In 2008 the professorship of public real estate started with its first Barometer for Social Real Estate. In 2009, I advocated in Real Estate Magazine that research into social real estate is necessary from the perspective of Corporate Real Estate Management (CREM) through new development models and more (PhD) research. In anticipation of the municipal elections of 2010, research by the research group Municipal Real Estate showed that social real estate was not a matter for the election programs of the political parties. This was a prelude to the funded RAAK subsidy application towards marketed municipal real estate for carrying out practice-oriented research. In 2012, this research led to the externally funded research group Social Real Estate. After that, the Social Real Estate professorship profiled itself in different areas. Extra media publicity has been generated primarily thanks to the attention of minister Stef Blok in 2014, when he received the first copy of the book Barometer Maatschappelijk Vastgoed (Social Real Estate): Corporate Social Responsibility at our annual congress, the round table meeting with State Secretary for Health, Welfare and Sport Martin van Rijn in 2015 and the informal conversation with the Minister of Education, Culture and Science Jet Bussemaker in 2015, as well as the many publications of the lectorate. In the 2016 debate with civil society with the Prime Minister Mark Rutte when handing over the book Barometer Maatschappelijk Vastgoed (Social Real Estate) 2016, a round table meeting in 2017 with Minister of Home Affairs and Kingdom Relations Stef Blok, aldermen and directors Real Estate of Municipalities in The Netherlands, have contributed to social and economic knowledge utilization for future and existing real estate professionals. At the PROVADA 2017 we co-organized ‘Shrink: Emptiness and Space for Innovation and Change’ session, where the Minister of the Home Affairs and Kingdom Relations Ronald Plasterk presented his vision on this subject
Frameshift mutations at the C-terminus of HIST1H1E result in a specific DNA hypomethylation signature
BACKGROUND: We previously associated HIST1H1E mutations causing Rahman syndrome with a specific genome-wide methylation pattern. RESULTS: Methylome analysis from peripheral blood samples of six affected subjects led us to identify a specific hypomethylated profile. This "episignature" was enriched for genes involved in neuronal system development and function. A computational classifier yielded full sensitivity and specificity in detecting subjects with Rahman syndrome. Applying this model to a cohort of undiagnosed probands allowed us to reach diagnosis in one subject. CONCLUSIONS: We demonstrate an epigenetic signature in subjects with Rahman syndrome that can be used to reach molecular diagnosis
Maine State Government Administrative Report 2013-2014
https://digitalmaine.com/me_annual_reports/1040/thumbnail.jp